Aspectos parasitológicos y epidemiológicos de los donantes de sangre seropositivos para Trypanosoma cruzi,en un hospital universitario

Background: After the interruption of the transmission of Chagas disease via vector insects in Chile, there is little available epidemiological information about this parasitosis in blood banks. Aim To update the rates of T cruzi positive blood donors. To measure parasitological and epidemiological...

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Autores principales:	Galaz,Pablo, García,Stephanie, Mercado,Rubén, Orrego,Elsa, Pagliero,Blanca, Contreras,María del Carmen, Salinas,Patricia, Arancibia,Carlos
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2007
Materias:	Blood donors Trypanosoma cruzi Xenodiagnosis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001000009
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spelling	oai:scielo:S0034-988720070010000092007-12-20Aspectos parasitológicos y epidemiológicos de los donantes de sangre seropositivos para Trypanosoma cruzi,en un hospital universitarioGalaz,PabloGarcía,StephanieMercado,RubénOrrego,ElsaPagliero,BlancaContreras,María del CarmenSalinas,PatriciaArancibia,Carlos Blood donors Trypanosoma cruzi Xenodiagnosis Background: After the interruption of the transmission of Chagas disease via vector insects in Chile, there is little available epidemiological information about this parasitosis in blood banks. Aim To update the rates of T cruzi positive blood donors. To measure parasitological and epidemiological parameters in blood donors with anti T cruzi antibodies. Material and Methods: An ELISA-T cruzi test was carried out in 30,309 blood donors between 2000 and 2004. In 75 blood donors with an ELISA-T cruzi positive test and 79 donors with negative ELISA (controls), a survey about personal or parental history of biting by a kissing bug (Triatomine), was performed. A blood sample was also obtained to perform Polymerase Chain Reaction (PCR) for T cruzi and a xenodiagnostic test. Results: Annual frequency of positive ELISA for T cruzi serum antibodies in blood donors varied from 0.31% to 0.45%. Twenty eight percent of subjects with positive and 6% of subjects with negative specific antibodies answered the survey about biting. PCR and xenodiagnostic test were positive in 52 (69%) and 16 (21%) of positive ELISA-T cruzi test blood donors, respectively. Xenodiagnostic was also positive in 5 individuals who had a negative PCR. Conclusions: Seroprevalence of T cruzi antibodies decreased from 3% in 1968 to 0.3% in 2004info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.10 20072007-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001000009es10.4067/S0034-98872007001000009
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Blood donors Trypanosoma cruzi Xenodiagnosis
spellingShingle	Blood donors Trypanosoma cruzi Xenodiagnosis Galaz,Pablo García,Stephanie Mercado,Rubén Orrego,Elsa Pagliero,Blanca Contreras,María del Carmen Salinas,Patricia Arancibia,Carlos Aspectos parasitológicos y epidemiológicos de los donantes de sangre seropositivos para Trypanosoma cruzi,en un hospital universitario
description	Background: After the interruption of the transmission of Chagas disease via vector insects in Chile, there is little available epidemiological information about this parasitosis in blood banks. Aim To update the rates of T cruzi positive blood donors. To measure parasitological and epidemiological parameters in blood donors with anti T cruzi antibodies. Material and Methods: An ELISA-T cruzi test was carried out in 30,309 blood donors between 2000 and 2004. In 75 blood donors with an ELISA-T cruzi positive test and 79 donors with negative ELISA (controls), a survey about personal or parental history of biting by a kissing bug (Triatomine), was performed. A blood sample was also obtained to perform Polymerase Chain Reaction (PCR) for T cruzi and a xenodiagnostic test. Results: Annual frequency of positive ELISA for T cruzi serum antibodies in blood donors varied from 0.31% to 0.45%. Twenty eight percent of subjects with positive and 6% of subjects with negative specific antibodies answered the survey about biting. PCR and xenodiagnostic test were positive in 52 (69%) and 16 (21%) of positive ELISA-T cruzi test blood donors, respectively. Xenodiagnostic was also positive in 5 individuals who had a negative PCR. Conclusions: Seroprevalence of T cruzi antibodies decreased from 3% in 1968 to 0.3% in 2004
author	Galaz,Pablo García,Stephanie Mercado,Rubén Orrego,Elsa Pagliero,Blanca Contreras,María del Carmen Salinas,Patricia Arancibia,Carlos
author_facet	Galaz,Pablo García,Stephanie Mercado,Rubén Orrego,Elsa Pagliero,Blanca Contreras,María del Carmen Salinas,Patricia Arancibia,Carlos
author_sort	Galaz,Pablo
title	Aspectos parasitológicos y epidemiológicos de los donantes de sangre seropositivos para Trypanosoma cruzi,en un hospital universitario
title_short	Aspectos parasitológicos y epidemiológicos de los donantes de sangre seropositivos para Trypanosoma cruzi,en un hospital universitario
title_full	Aspectos parasitológicos y epidemiológicos de los donantes de sangre seropositivos para Trypanosoma cruzi,en un hospital universitario
title_fullStr	Aspectos parasitológicos y epidemiológicos de los donantes de sangre seropositivos para Trypanosoma cruzi,en un hospital universitario
title_full_unstemmed	Aspectos parasitológicos y epidemiológicos de los donantes de sangre seropositivos para Trypanosoma cruzi,en un hospital universitario
title_sort	aspectos parasitológicos y epidemiológicos de los donantes de sangre seropositivos para trypanosoma cruzi,en un hospital universitario
publisher	Sociedad Médica de Santiago
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001000009
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Aspectos parasitológicos y epidemiológicos de los donantes de sangre seropositivos para Trypanosoma cruzi,en un hospital universitario

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