Hipokalemia, hipovolemia y repercusión electrocardiográfica secundarias a ingesta prolongada de furosemida: Caso clínico
Hypokalemia (serum K+ < 3.5 mEq/1) is a potentially serious adverse effect of diuretic ingestión. We report a 27 year-old woman admitted with muscle weakness, a serum potassium of 2.0 mEq/1, metabolic alkalosis and EKG abnormalities simulating cardiac ischemia, that reverted with potassium chlori...
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| Lenguaje: | Spanish / Castilian |
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Sociedad Médica de Santiago
2007
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oai:scielo:S0034-988720070011000132008-02-08Hipokalemia, hipovolemia y repercusión electrocardiográfica secundarias a ingesta prolongada de furosemida: Caso clínicoAravena,CésarSalas,IgnacioTagle,RodrigoJara,AquilesMiranda,RodrigoMcNab,PaulRodríguez,José AValdés,GloriaValdivieso,Andrés Furosemide Hypokalemia Hypovolemia Hypokalemia (serum K+ < 3.5 mEq/1) is a potentially serious adverse effect of diuretic ingestión. We report a 27 year-old woman admitted with muscle weakness, a serum potassium of 2.0 mEq/1, metabolic alkalosis and EKG abnormalities simulating cardiac ischemia, that reverted with potassium chloride administration. She admitted high dose furosemide self-medication for edema. Glomerular filtration rate, tubular sodium reabsortion, potassium secretion, the renin-aldosterone system, total body water distribution and capillary permeability, were studied sequentially until 90 days after her admission. There was hyperactivity of the renin-aldosterone axis, reduction in extracellular and intracellular volumes, normal capillary permeability and high sodium tubular reabsorption, probably explained by a "rebound" salt retention associated with her decreased extracellular volumeinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.11 20072007-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001100013es10.4067/S0034-98872007001100013 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
Spanish / Castilian |
| topic |
Furosemide Hypokalemia Hypovolemia |
| spellingShingle |
Furosemide Hypokalemia Hypovolemia Aravena,César Salas,Ignacio Tagle,Rodrigo Jara,Aquiles Miranda,Rodrigo McNab,Paul Rodríguez,José A Valdés,Gloria Valdivieso,Andrés Hipokalemia, hipovolemia y repercusión electrocardiográfica secundarias a ingesta prolongada de furosemida: Caso clínico |
| description |
Hypokalemia (serum K+ < 3.5 mEq/1) is a potentially serious adverse effect of diuretic ingestión. We report a 27 year-old woman admitted with muscle weakness, a serum potassium of 2.0 mEq/1, metabolic alkalosis and EKG abnormalities simulating cardiac ischemia, that reverted with potassium chloride administration. She admitted high dose furosemide self-medication for edema. Glomerular filtration rate, tubular sodium reabsortion, potassium secretion, the renin-aldosterone system, total body water distribution and capillary permeability, were studied sequentially until 90 days after her admission. There was hyperactivity of the renin-aldosterone axis, reduction in extracellular and intracellular volumes, normal capillary permeability and high sodium tubular reabsorption, probably explained by a "rebound" salt retention associated with her decreased extracellular volume |
| author |
Aravena,César Salas,Ignacio Tagle,Rodrigo Jara,Aquiles Miranda,Rodrigo McNab,Paul Rodríguez,José A Valdés,Gloria Valdivieso,Andrés |
| author_facet |
Aravena,César Salas,Ignacio Tagle,Rodrigo Jara,Aquiles Miranda,Rodrigo McNab,Paul Rodríguez,José A Valdés,Gloria Valdivieso,Andrés |
| author_sort |
Aravena,César |
| title |
Hipokalemia, hipovolemia y repercusión electrocardiográfica secundarias a ingesta prolongada de furosemida: Caso clínico |
| title_short |
Hipokalemia, hipovolemia y repercusión electrocardiográfica secundarias a ingesta prolongada de furosemida: Caso clínico |
| title_full |
Hipokalemia, hipovolemia y repercusión electrocardiográfica secundarias a ingesta prolongada de furosemida: Caso clínico |
| title_fullStr |
Hipokalemia, hipovolemia y repercusión electrocardiográfica secundarias a ingesta prolongada de furosemida: Caso clínico |
| title_full_unstemmed |
Hipokalemia, hipovolemia y repercusión electrocardiográfica secundarias a ingesta prolongada de furosemida: Caso clínico |
| title_sort |
hipokalemia, hipovolemia y repercusión electrocardiográfica secundarias a ingesta prolongada de furosemida: caso clínico |
| publisher |
Sociedad Médica de Santiago |
| publishDate |
2007 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001100013 |
| work_keys_str_mv |
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