Síndrome de ovario poliquístico (SOP) y embarazo: Experiencia clínica

Background: Polycystic ovary syndrome (PCOS) is an endocrine metabolic dysfunction closely associated with insulin resistance and obesity, which predisposes to pregnancy complications. Aim: To report a prospective clinical experience in PCOS patients who became pregnant after diet, exercise and metf...

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Autores principales:	Villarroel,Ana Claudia, Echiburú,Bárbara, Riesco,Virginia, Maliqueo,Manuel, Cárcamo,Michael, Hitschfeld,Catalina, Sánchez,Fernando, del Solar,María Paz, Sir-Petermann,Teresa
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2007
Materias:	Diabetes gestational Polycystic ovary syndrome Pregnancy complications
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001200005
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spelling	oai:scielo:S0034-988720070012000052014-01-06Síndrome de ovario poliquístico (SOP) y embarazo: Experiencia clínicaVillarroel,Ana ClaudiaEchiburú,BárbaraRiesco,VirginiaMaliqueo,ManuelCárcamo,MichaelHitschfeld,CatalinaSánchez,Fernandodel Solar,María PazSir-Petermann,Teresa Diabetes gestational Polycystic ovary syndrome Pregnancy complications Background: Polycystic ovary syndrome (PCOS) is an endocrine metabolic dysfunction closely associated with insulin resistance and obesity, which predisposes to pregnancy complications. Aim: To report a prospective clinical experience in PCOS patients who became pregnant after diet, exercise and metformin treatment intervention, and were followed up during the whole pregnancy. Patients and Methods: Seventy pregnant PCOS (PPCOS) women and forty normal pregnant (NP) women of similar age and with singleton pregnancies were included in the study. During gestational ages 10-16 and 22-28 weeks, a 2h, 75 g oral glucose tolerance test (OGTT) was performed with measurement of glucose and insulin in each sample. Results: No differences were found in duration of gestation, weight gain during pregnancy, or systolic and diastolic blood pressure between PPCOS and NP women. There were significant differences in body mass index (BMI) at the initiation and in the third trimester of pregnancy between both groups. The incidence of gestational diabetes was significantly higher (p <0.01) in the PCOS group (35.2%) compared to the control group (5.0%). The prevalence of small for gestational age (SGA) infants tended to be higher (p =0.09) in the PCOS group. During pregnancy, 2h glucose and insulin were significantly higher in PPCOS than in NP women. Conclusions: PCOS mothers showed a higher prevalence of gestational diabetes and SGA newborns, which cannot be attributed to the weight gain during pregnancy, and seems to be more related to the BMI at the initiation of pregnancy, and to the PCOS condition of the motheinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.12 20072007-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001200005es10.4067/S0034-98872007001200005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Diabetes gestational Polycystic ovary syndrome Pregnancy complications
spellingShingle	Diabetes gestational Polycystic ovary syndrome Pregnancy complications Villarroel,Ana Claudia Echiburú,Bárbara Riesco,Virginia Maliqueo,Manuel Cárcamo,Michael Hitschfeld,Catalina Sánchez,Fernando del Solar,María Paz Sir-Petermann,Teresa Síndrome de ovario poliquístico (SOP) y embarazo: Experiencia clínica
description	Background: Polycystic ovary syndrome (PCOS) is an endocrine metabolic dysfunction closely associated with insulin resistance and obesity, which predisposes to pregnancy complications. Aim: To report a prospective clinical experience in PCOS patients who became pregnant after diet, exercise and metformin treatment intervention, and were followed up during the whole pregnancy. Patients and Methods: Seventy pregnant PCOS (PPCOS) women and forty normal pregnant (NP) women of similar age and with singleton pregnancies were included in the study. During gestational ages 10-16 and 22-28 weeks, a 2h, 75 g oral glucose tolerance test (OGTT) was performed with measurement of glucose and insulin in each sample. Results: No differences were found in duration of gestation, weight gain during pregnancy, or systolic and diastolic blood pressure between PPCOS and NP women. There were significant differences in body mass index (BMI) at the initiation and in the third trimester of pregnancy between both groups. The incidence of gestational diabetes was significantly higher (p <0.01) in the PCOS group (35.2%) compared to the control group (5.0%). The prevalence of small for gestational age (SGA) infants tended to be higher (p =0.09) in the PCOS group. During pregnancy, 2h glucose and insulin were significantly higher in PPCOS than in NP women. Conclusions: PCOS mothers showed a higher prevalence of gestational diabetes and SGA newborns, which cannot be attributed to the weight gain during pregnancy, and seems to be more related to the BMI at the initiation of pregnancy, and to the PCOS condition of the mothe
author	Villarroel,Ana Claudia Echiburú,Bárbara Riesco,Virginia Maliqueo,Manuel Cárcamo,Michael Hitschfeld,Catalina Sánchez,Fernando del Solar,María Paz Sir-Petermann,Teresa
author_facet	Villarroel,Ana Claudia Echiburú,Bárbara Riesco,Virginia Maliqueo,Manuel Cárcamo,Michael Hitschfeld,Catalina Sánchez,Fernando del Solar,María Paz Sir-Petermann,Teresa
author_sort	Villarroel,Ana Claudia
title	Síndrome de ovario poliquístico (SOP) y embarazo: Experiencia clínica
title_short	Síndrome de ovario poliquístico (SOP) y embarazo: Experiencia clínica
title_full	Síndrome de ovario poliquístico (SOP) y embarazo: Experiencia clínica
title_fullStr	Síndrome de ovario poliquístico (SOP) y embarazo: Experiencia clínica
title_full_unstemmed	Síndrome de ovario poliquístico (SOP) y embarazo: Experiencia clínica
title_sort	síndrome de ovario poliquístico (sop) y embarazo: experiencia clínica
publisher	Sociedad Médica de Santiago
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001200005
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Síndrome de ovario poliquístico (SOP) y embarazo: Experiencia clínica

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