Inmunoterapia con veneno de himenópteros: presentación de diez casos clínicos

Background: Immunotherapy can be used to treat allergic reactions to insect stings, specially bees and wasps. Aim: To report the experience with immunotherapy with aqueous extracts of hymenoptera venoms (bees and wasps). Material and methods: Ten patients aged 6 to 58 years were treated in an allerg...

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Autores principales: Guzmán M,María Antonieta, Salinas L,Jessica, Toche P,Paola, Marinovic M,María Angélica, Gallardo O,Ana María
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2007
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001200010
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spelling oai:scielo:S0034-988720070012000102014-01-06Inmunoterapia con veneno de himenópteros: presentación de diez casos clínicosGuzmán M,María AntonietaSalinas L,JessicaToche P,PaolaMarinovic M,María AngélicaGallardo O,Ana María Desensitization, immunologic Hymenoptera Hypersensitivity Venoms Background: Immunotherapy can be used to treat allergic reactions to insect stings, specially bees and wasps. Aim: To report the experience with immunotherapy with aqueous extracts of hymenoptera venoms (bees and wasps). Material and methods: Ten patients aged 6 to 58 years were treated in an allergy center of a University Clinical Hospital. The medical indication for this treatment was, in all patients, anaphylactic reactions after hymenoptera stings. Immunotherapy was carried out using standardized vaccines (Aqueous extracts Venomvac LETI, Spain), applied in a traditional protocol, with subcutaneous injections. This protocol had two phases: a buildup phase (between weeks 1 and 13) and a monthly maintenance phase, from the 13th week. The monthly maintenance dose was 100 fig of hymenoptera specific venom extract. Results: Six patients had adverse reactions of different severity, during the treatment protocols and all had a good response to immediate therapeutic measures. After these events, they followed the protocol without problems. Two patients, treated with bee vaccines, suffered an accidental bee sting during the maintenance phase and they developed only local reactions. Conclusions: The lack of adverse reactions to bee stings in these two patients indicates the acquisition of clinical toleranceinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.12 20072007-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001200010es10.4067/S0034-98872007001200010
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Desensitization, immunologic
Hymenoptera
Hypersensitivity
Venoms
spellingShingle Desensitization, immunologic
Hymenoptera
Hypersensitivity
Venoms
Guzmán M,María Antonieta
Salinas L,Jessica
Toche P,Paola
Marinovic M,María Angélica
Gallardo O,Ana María
Inmunoterapia con veneno de himenópteros: presentación de diez casos clínicos
description Background: Immunotherapy can be used to treat allergic reactions to insect stings, specially bees and wasps. Aim: To report the experience with immunotherapy with aqueous extracts of hymenoptera venoms (bees and wasps). Material and methods: Ten patients aged 6 to 58 years were treated in an allergy center of a University Clinical Hospital. The medical indication for this treatment was, in all patients, anaphylactic reactions after hymenoptera stings. Immunotherapy was carried out using standardized vaccines (Aqueous extracts Venomvac LETI, Spain), applied in a traditional protocol, with subcutaneous injections. This protocol had two phases: a buildup phase (between weeks 1 and 13) and a monthly maintenance phase, from the 13th week. The monthly maintenance dose was 100 fig of hymenoptera specific venom extract. Results: Six patients had adverse reactions of different severity, during the treatment protocols and all had a good response to immediate therapeutic measures. After these events, they followed the protocol without problems. Two patients, treated with bee vaccines, suffered an accidental bee sting during the maintenance phase and they developed only local reactions. Conclusions: The lack of adverse reactions to bee stings in these two patients indicates the acquisition of clinical tolerance
author Guzmán M,María Antonieta
Salinas L,Jessica
Toche P,Paola
Marinovic M,María Angélica
Gallardo O,Ana María
author_facet Guzmán M,María Antonieta
Salinas L,Jessica
Toche P,Paola
Marinovic M,María Angélica
Gallardo O,Ana María
author_sort Guzmán M,María Antonieta
title Inmunoterapia con veneno de himenópteros: presentación de diez casos clínicos
title_short Inmunoterapia con veneno de himenópteros: presentación de diez casos clínicos
title_full Inmunoterapia con veneno de himenópteros: presentación de diez casos clínicos
title_fullStr Inmunoterapia con veneno de himenópteros: presentación de diez casos clínicos
title_full_unstemmed Inmunoterapia con veneno de himenópteros: presentación de diez casos clínicos
title_sort inmunoterapia con veneno de himenópteros: presentación de diez casos clínicos
publisher Sociedad Médica de Santiago
publishDate 2007
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001200010
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AT tocheppaola inmunoterapiaconvenenodehimenopterospresentaciondediezcasosclinicos
AT marinovicmmariaangelica inmunoterapiaconvenenodehimenopterospresentaciondediezcasosclinicos
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