Púrpura trombocitopénico trombótico con respuesta exitosa a vincristina

Thrombotic thrombocytopenic purpura presents as a multisystemic disease with thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological and renal involvement. We report a 24 years-old male presenting with purpura and a generalized seizure. His blood tests showed an hemolytic anemia, un...

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Autores principales:	Espinoza,Francisco, Leal,José Luis, Arenas,Guillermo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2007
Materias:	Purpura, thrombocytopenic Purpura, thrombotic thrombocytopenic vincristine
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001200011
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spelling	oai:scielo:S0034-988720070012000112014-01-06Púrpura trombocitopénico trombótico con respuesta exitosa a vincristinaEspinoza,FranciscoLeal,José LuisArenas,Guillermo Purpura, thrombocytopenic Purpura, thrombotic thrombocytopenic vincristine Thrombotic thrombocytopenic purpura presents as a multisystemic disease with thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological and renal involvement. We report a 24 years-old male presenting with purpura and a generalized seizure. His blood tests showed an hemolytic anemia, unconjungated hyperbilirubinemia, increased lactated dehydrogenase, thrombocytopenia and impairment of renal function. He was initially treated with daily plasmapheresis and steroids without improvement. Due to persistence of the disease, he was treated with two doses of intravenous vincristine in four days, with clinical and laboratory improvement. He was discharged 40 days after the last dose of vincristine, in good conditionsinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.12 20072007-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001200011es10.4067/S0034-98872007001200011
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Purpura, thrombocytopenic Purpura, thrombotic thrombocytopenic vincristine
spellingShingle	Purpura, thrombocytopenic Purpura, thrombotic thrombocytopenic vincristine Espinoza,Francisco Leal,José Luis Arenas,Guillermo Púrpura trombocitopénico trombótico con respuesta exitosa a vincristina
description	Thrombotic thrombocytopenic purpura presents as a multisystemic disease with thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological and renal involvement. We report a 24 years-old male presenting with purpura and a generalized seizure. His blood tests showed an hemolytic anemia, unconjungated hyperbilirubinemia, increased lactated dehydrogenase, thrombocytopenia and impairment of renal function. He was initially treated with daily plasmapheresis and steroids without improvement. Due to persistence of the disease, he was treated with two doses of intravenous vincristine in four days, with clinical and laboratory improvement. He was discharged 40 days after the last dose of vincristine, in good conditions
author	Espinoza,Francisco Leal,José Luis Arenas,Guillermo
author_facet	Espinoza,Francisco Leal,José Luis Arenas,Guillermo
author_sort	Espinoza,Francisco
title	Púrpura trombocitopénico trombótico con respuesta exitosa a vincristina
title_short	Púrpura trombocitopénico trombótico con respuesta exitosa a vincristina
title_full	Púrpura trombocitopénico trombótico con respuesta exitosa a vincristina
title_fullStr	Púrpura trombocitopénico trombótico con respuesta exitosa a vincristina
title_full_unstemmed	Púrpura trombocitopénico trombótico con respuesta exitosa a vincristina
title_sort	púrpura trombocitopénico trombótico con respuesta exitosa a vincristina
publisher	Sociedad Médica de Santiago
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007001200011
work_keys_str_mv	AT espinozafrancisco purpuratrombocitopenicotromboticoconrespuestaexitosaavincristina AT lealjoseluis purpuratrombocitopenicotromboticoconrespuestaexitosaavincristina AT arenasguillermo purpuratrombocitopenicotromboticoconrespuestaexitosaavincristina
_version_	1718436354824601600

Púrpura trombocitopénico trombótico con respuesta exitosa a vincristina

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