Leucoencefalopatía reversible posterior: cuatro casos clínicos

Reversible posterior leukoencephalopathy syndrome (PLS) is characterized by headache, clouding of sensorium, visual disturbances and seizures. It is associated to hypertension, renal disease or immunosuppressive therapy. We report three males, aged 9, 12 and 16 years and one female, aged 5 years wih...

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Autores principales:	Hernández Ch,Marta, Núñez F,Alicia, Mesa L,Tomas, Escobar H,Raúl, Barriga C,Francisco, Huete L,Isidro
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2008
Materias:	Immunosupression Posterior leukoencephalopathy syndrome Tacrolimus
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000100012
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spelling	oai:scielo:S0034-988720080001000122008-04-30Leucoencefalopatía reversible posterior: cuatro casos clínicosHernández Ch,MartaNúñez F,AliciaMesa L,TomasEscobar H,RaúlBarriga C,FranciscoHuete L,Isidro Immunosupression Posterior leukoencephalopathy syndrome Tacrolimus Reversible posterior leukoencephalopathy syndrome (PLS) is characterized by headache, clouding of sensorium, visual disturbances and seizures. It is associated to hypertension, renal disease or immunosuppressive therapy. We report three males, aged 9, 12 and 16 years and one female, aged 5 years wih PLS associated to immunosuppressive therapy. All had seizures and three had headache and clouding of sensorium. One case was associated to an hypertensive emergency, one to liver failure and one to high tacrolimus levels. Magnetic resonance imaging showed lesions in the white matter in two patients and in the gray matter in the other two. The lapse between the start of immunosuppressive treatment and neurological symptoms ranged from 4 days to 6 months. All received antiepileptic drugs and immunosuppresive therapy was changed or decreased, with complete clinical recovery (Rev Méd Chile 2008, 136: 93-8)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.1 20082008-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000100012es10.4067/S0034-98872008000100012
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Immunosupression Posterior leukoencephalopathy syndrome Tacrolimus
spellingShingle	Immunosupression Posterior leukoencephalopathy syndrome Tacrolimus Hernández Ch,Marta Núñez F,Alicia Mesa L,Tomas Escobar H,Raúl Barriga C,Francisco Huete L,Isidro Leucoencefalopatía reversible posterior: cuatro casos clínicos
description	Reversible posterior leukoencephalopathy syndrome (PLS) is characterized by headache, clouding of sensorium, visual disturbances and seizures. It is associated to hypertension, renal disease or immunosuppressive therapy. We report three males, aged 9, 12 and 16 years and one female, aged 5 years wih PLS associated to immunosuppressive therapy. All had seizures and three had headache and clouding of sensorium. One case was associated to an hypertensive emergency, one to liver failure and one to high tacrolimus levels. Magnetic resonance imaging showed lesions in the white matter in two patients and in the gray matter in the other two. The lapse between the start of immunosuppressive treatment and neurological symptoms ranged from 4 days to 6 months. All received antiepileptic drugs and immunosuppresive therapy was changed or decreased, with complete clinical recovery (Rev Méd Chile 2008, 136: 93-8)
author	Hernández Ch,Marta Núñez F,Alicia Mesa L,Tomas Escobar H,Raúl Barriga C,Francisco Huete L,Isidro
author_facet	Hernández Ch,Marta Núñez F,Alicia Mesa L,Tomas Escobar H,Raúl Barriga C,Francisco Huete L,Isidro
author_sort	Hernández Ch,Marta
title	Leucoencefalopatía reversible posterior: cuatro casos clínicos
title_short	Leucoencefalopatía reversible posterior: cuatro casos clínicos
title_full	Leucoencefalopatía reversible posterior: cuatro casos clínicos
title_fullStr	Leucoencefalopatía reversible posterior: cuatro casos clínicos
title_full_unstemmed	Leucoencefalopatía reversible posterior: cuatro casos clínicos
title_sort	leucoencefalopatía reversible posterior: cuatro casos clínicos
publisher	Sociedad Médica de Santiago
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000100012
work_keys_str_mv	AT hernandezchmarta leucoencefalopatiareversibleposteriorcuatrocasosclinicos AT nunezfalicia leucoencefalopatiareversibleposteriorcuatrocasosclinicos AT mesaltomas leucoencefalopatiareversibleposteriorcuatrocasosclinicos AT escobarhraul leucoencefalopatiareversibleposteriorcuatrocasosclinicos AT barrigacfrancisco leucoencefalopatiareversibleposteriorcuatrocasosclinicos AT huetelisidro leucoencefalopatiareversibleposteriorcuatrocasosclinicos
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Leucoencefalopatía reversible posterior: cuatro casos clínicos

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