La edad paterna como factor de riesgo para malformaciones congénitas

The role of advanced maternal age as a risk factor for congenital malformations in offspring is known. However, the influence of paternal age is not clear. Aim: To evaluate the association between advanced paternal age and the risk for congenital malformations. Patients and Methods: Analysis of mate...

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Autores principales:	Nazer H,Julio, Cifuentes O,Lucía, Millán Z,Francisca, Vacarisas A,Paola, Köbrich Sch,Stephanie, Aguila R,Alfredo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2008
Materias:	Fathers Infant newborn Malformations congenital
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000200009
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spelling	oai:scielo:S0034-988720080002000092008-07-28La edad paterna como factor de riesgo para malformaciones congénitasNazer H,JulioCifuentes O,LucíaMillán Z,FranciscaVacarisas A,PaolaKöbrich Sch,StephanieAguila R,Alfredo Fathers Infant newborn Malformations congenital The role of advanced maternal age as a risk factor for congenital malformations in offspring is known. However, the influence of paternal age is not clear. Aim: To evaluate the association between advanced paternal age and the risk for congenital malformations. Patients and Methods: Analysis of maternal and paternal age of cases (malformed newborns) and controls from ECLAMC Database (Latin American Collaborative Study of Congenital Malformations) registered at the University of Chile Clinical Hospital during the decade from Jan 1 1997 to Dec 31 2006. Newborns and stillborns were grouped according to maternal age into 6 intervals. In each interval, paternal ages of cases and controls were compared. The inverse procedure was performed to assess maternal age effect. Other variables as gestational age and birth weight were analyzed for the intervals of maternal and paternal ages. Results: No significant differences were observed in paternal age between cases and controls in any of the intervals of maternal age. However, mean maternal age was higher for cases than for controls (p =0,0149). Gestational age and birth weight depend more on being case or control than on the age of parents. Conclusions: No differences in paternal age were observed between cases and controls in this series of newbornsinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.2 20082008-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000200009es10.4067/S0034-98872008000200009
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Fathers Infant newborn Malformations congenital
spellingShingle	Fathers Infant newborn Malformations congenital Nazer H,Julio Cifuentes O,Lucía Millán Z,Francisca Vacarisas A,Paola Köbrich Sch,Stephanie Aguila R,Alfredo La edad paterna como factor de riesgo para malformaciones congénitas
description	The role of advanced maternal age as a risk factor for congenital malformations in offspring is known. However, the influence of paternal age is not clear. Aim: To evaluate the association between advanced paternal age and the risk for congenital malformations. Patients and Methods: Analysis of maternal and paternal age of cases (malformed newborns) and controls from ECLAMC Database (Latin American Collaborative Study of Congenital Malformations) registered at the University of Chile Clinical Hospital during the decade from Jan 1 1997 to Dec 31 2006. Newborns and stillborns were grouped according to maternal age into 6 intervals. In each interval, paternal ages of cases and controls were compared. The inverse procedure was performed to assess maternal age effect. Other variables as gestational age and birth weight were analyzed for the intervals of maternal and paternal ages. Results: No significant differences were observed in paternal age between cases and controls in any of the intervals of maternal age. However, mean maternal age was higher for cases than for controls (p =0,0149). Gestational age and birth weight depend more on being case or control than on the age of parents. Conclusions: No differences in paternal age were observed between cases and controls in this series of newborns
author	Nazer H,Julio Cifuentes O,Lucía Millán Z,Francisca Vacarisas A,Paola Köbrich Sch,Stephanie Aguila R,Alfredo
author_facet	Nazer H,Julio Cifuentes O,Lucía Millán Z,Francisca Vacarisas A,Paola Köbrich Sch,Stephanie Aguila R,Alfredo
author_sort	Nazer H,Julio
title	La edad paterna como factor de riesgo para malformaciones congénitas
title_short	La edad paterna como factor de riesgo para malformaciones congénitas
title_full	La edad paterna como factor de riesgo para malformaciones congénitas
title_fullStr	La edad paterna como factor de riesgo para malformaciones congénitas
title_full_unstemmed	La edad paterna como factor de riesgo para malformaciones congénitas
title_sort	la edad paterna como factor de riesgo para malformaciones congénitas
publisher	Sociedad Médica de Santiago
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000200009
work_keys_str_mv	AT nazerhjulio laedadpaternacomofactorderiesgoparamalformacionescongenitas AT cifuentesolucia laedadpaternacomofactorderiesgoparamalformacionescongenitas AT millanzfrancisca laedadpaternacomofactorderiesgoparamalformacionescongenitas AT vacarisasapaola laedadpaternacomofactorderiesgoparamalformacionescongenitas AT kobrichschstephanie laedadpaternacomofactorderiesgoparamalformacionescongenitas AT aguilaralfredo laedadpaternacomofactorderiesgoparamalformacionescongenitas
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La edad paterna como factor de riesgo para malformaciones congénitas

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