Presencia de metalo-ß-lactamasas en Pseudomonas aeruginosa resistente a imipenem

Background: Metallo-ß-lactamases (MBL) confer high resistance to carbapenems in Pseudomonas aeruginosa (Psae). They are encoded in mobile elements of different genes (VIM, IMP, SMP, GIM), along with other resistance genes. Aim: To detect the presence of MBL in imipenem resistant Psae strains. Materi...

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Autores principales:	Pérez I,Alfonso, García C,Patricia, Poggi M,Helena, Braun J,Stephanie, Castillo V,Claudia, Román,Juan Carlos, Lagos,Marcela, Romeo 0,Eliana, Porte T,Lorena, Labarca L,Jaime, González R,Gerardo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2008
Materias:	Beta-Lactamases Imipenem Pseudomonas aeruginosa
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000400002
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id	oai:scielo:S0034-98872008000400002
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spelling	oai:scielo:S0034-988720080004000022008-06-16Presencia de metalo-ß-lactamasas en Pseudomonas aeruginosa resistente a imipenemPérez I,AlfonsoGarcía C,PatriciaPoggi M,HelenaBraun J,StephanieCastillo V,ClaudiaRomán,Juan CarlosLagos,MarcelaRomeo 0,ElianaPorte T,LorenaLabarca L,JaimeGonzález R,Gerardo Beta-Lactamases Imipenem Pseudomonas aeruginosa Background: Metallo-ß-lactamases (MBL) confer high resistance to carbapenems in Pseudomonas aeruginosa (Psae). They are encoded in mobile elements of different genes (VIM, IMP, SMP, GIM), along with other resistance genes. Aim: To detect the presence of MBL in imipenem resistant Psae strains. Material and methods: Fifty-nine imipenem resistant Psae strains isolated from January 2004 to August 2005 in a University Clinical Hospital, were included. The presence of MBL was studied by Etest (phenotypic) and genotypic polymerase chain reaction (PCR) methods. To rule out a nosocomial outbreak, MBL positive strains, were studied by pulse field gel electrophoresis. Results: The presente of MBL was detected in eleven strains. AH were type VIM and were not clonally related. There was no concordance between phenotypic and genotypic MBL detecting methods. AH the strains were also multiresistant. Conclusions: The presence of MBL was detected in 19% of imipenem resistant Psae strainsinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.4 20082008-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000400002es10.4067/S0034-98872008000400002
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Beta-Lactamases Imipenem Pseudomonas aeruginosa
spellingShingle	Beta-Lactamases Imipenem Pseudomonas aeruginosa Pérez I,Alfonso García C,Patricia Poggi M,Helena Braun J,Stephanie Castillo V,Claudia Román,Juan Carlos Lagos,Marcela Romeo 0,Eliana Porte T,Lorena Labarca L,Jaime González R,Gerardo Presencia de metalo-ß-lactamasas en Pseudomonas aeruginosa resistente a imipenem
description	Background: Metallo-ß-lactamases (MBL) confer high resistance to carbapenems in Pseudomonas aeruginosa (Psae). They are encoded in mobile elements of different genes (VIM, IMP, SMP, GIM), along with other resistance genes. Aim: To detect the presence of MBL in imipenem resistant Psae strains. Material and methods: Fifty-nine imipenem resistant Psae strains isolated from January 2004 to August 2005 in a University Clinical Hospital, were included. The presence of MBL was studied by Etest (phenotypic) and genotypic polymerase chain reaction (PCR) methods. To rule out a nosocomial outbreak, MBL positive strains, were studied by pulse field gel electrophoresis. Results: The presente of MBL was detected in eleven strains. AH were type VIM and were not clonally related. There was no concordance between phenotypic and genotypic MBL detecting methods. AH the strains were also multiresistant. Conclusions: The presence of MBL was detected in 19% of imipenem resistant Psae strains
author	Pérez I,Alfonso García C,Patricia Poggi M,Helena Braun J,Stephanie Castillo V,Claudia Román,Juan Carlos Lagos,Marcela Romeo 0,Eliana Porte T,Lorena Labarca L,Jaime González R,Gerardo
author_facet	Pérez I,Alfonso García C,Patricia Poggi M,Helena Braun J,Stephanie Castillo V,Claudia Román,Juan Carlos Lagos,Marcela Romeo 0,Eliana Porte T,Lorena Labarca L,Jaime González R,Gerardo
author_sort	Pérez I,Alfonso
title	Presencia de metalo-ß-lactamasas en Pseudomonas aeruginosa resistente a imipenem
title_short	Presencia de metalo-ß-lactamasas en Pseudomonas aeruginosa resistente a imipenem
title_full	Presencia de metalo-ß-lactamasas en Pseudomonas aeruginosa resistente a imipenem
title_fullStr	Presencia de metalo-ß-lactamasas en Pseudomonas aeruginosa resistente a imipenem
title_full_unstemmed	Presencia de metalo-ß-lactamasas en Pseudomonas aeruginosa resistente a imipenem
title_sort	presencia de metalo-ß-lactamasas en pseudomonas aeruginosa resistente a imipenem
publisher	Sociedad Médica de Santiago
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000400002
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Presencia de metalo-ß-lactamasas en Pseudomonas aeruginosa resistente a imipenem

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