Función renal en cirugía cardíaca con circulación extracorpórea: Pacientes valvulares y coronarios

Background: Patients with valvular heart disease are at high risk of acute renal failure after surgery with extracorporeal circulation. Aim: To describe changes in renal function parameters during surgery with extracorporeal circulation in patients with valvular heart disease and compare them with t...

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Autores principales:	Lema,Guillermo, Canessa,Roberto, Urzúa,Jorge, Jalil,Roberto, Morán,Sergio, Carvajal,Claudia, Aeschlimann,Nicolás, Merino,Waldo, Jaque,María P
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2008
Materias:	Extracorporeal circulation Kidney failure Thoracic surgery
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000400006
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spelling	oai:scielo:S0034-988720080004000062008-06-16Función renal en cirugía cardíaca con circulación extracorpórea: Pacientes valvulares y coronariosLema,GuillermoCanessa,RobertoUrzúa,JorgeJalil,RobertoMorán,SergioCarvajal,ClaudiaAeschlimann,NicolásMerino,WaldoJaque,María P Extracorporeal circulation Kidney failure Thoracic surgery Background: Patients with valvular heart disease are at high risk of acute renal failure after surgery with extracorporeal circulation. Aim: To describe changes in renal function parameters during surgery with extracorporeal circulation in patients with valvular heart disease and compare them with those found in patients undergoing elective coronary surgery Material and Methods: Two groups of patients were studied. Group 1 was composed by twelve patients undergoing elective coronary surgery and group 2 was composed by eleven patients undergoing surgery for heart valve replacement. Glomerular filtration rate and effective renal plasma now were estimated from inulin and the 131 I-hippuran clearance respectively, at five different times, during surgery and the postoperative period. Sodium filtration fraction and fractional excretion were calculated. Alpha and pi-glutathione s-transferase in urine were measured as markers of tubular damage in the pre and postoperative periods. Results: Effective renal plasma flow was reduced in both groups before induction of anesthesia, did not change during surgery and decreased significantly in patients with valvular disease in the postoperative period. Glomerular filtration rates were normal during all the study period. There was a non significant reduction of filtration fraction during extracorporeal circulation. Alpha and pi glutathione s-transferases were normal and did not change. Fractional excretion of sodium increased significantly postoperatively Conclusions: In patients with valvular disease undergoing surgery with extracorporeal circulation, renal function does not deteriorate. No significant difference was found when compared with patients undergoing coronary surgery. No evidence of functional and cellular renal disfunction or damage was found in both study groupsinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.4 20082008-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000400006es10.4067/S0034-98872008000400006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Extracorporeal circulation Kidney failure Thoracic surgery
spellingShingle	Extracorporeal circulation Kidney failure Thoracic surgery Lema,Guillermo Canessa,Roberto Urzúa,Jorge Jalil,Roberto Morán,Sergio Carvajal,Claudia Aeschlimann,Nicolás Merino,Waldo Jaque,María P Función renal en cirugía cardíaca con circulación extracorpórea: Pacientes valvulares y coronarios
description	Background: Patients with valvular heart disease are at high risk of acute renal failure after surgery with extracorporeal circulation. Aim: To describe changes in renal function parameters during surgery with extracorporeal circulation in patients with valvular heart disease and compare them with those found in patients undergoing elective coronary surgery Material and Methods: Two groups of patients were studied. Group 1 was composed by twelve patients undergoing elective coronary surgery and group 2 was composed by eleven patients undergoing surgery for heart valve replacement. Glomerular filtration rate and effective renal plasma now were estimated from inulin and the 131 I-hippuran clearance respectively, at five different times, during surgery and the postoperative period. Sodium filtration fraction and fractional excretion were calculated. Alpha and pi-glutathione s-transferase in urine were measured as markers of tubular damage in the pre and postoperative periods. Results: Effective renal plasma flow was reduced in both groups before induction of anesthesia, did not change during surgery and decreased significantly in patients with valvular disease in the postoperative period. Glomerular filtration rates were normal during all the study period. There was a non significant reduction of filtration fraction during extracorporeal circulation. Alpha and pi glutathione s-transferases were normal and did not change. Fractional excretion of sodium increased significantly postoperatively Conclusions: In patients with valvular disease undergoing surgery with extracorporeal circulation, renal function does not deteriorate. No significant difference was found when compared with patients undergoing coronary surgery. No evidence of functional and cellular renal disfunction or damage was found in both study groups
author	Lema,Guillermo Canessa,Roberto Urzúa,Jorge Jalil,Roberto Morán,Sergio Carvajal,Claudia Aeschlimann,Nicolás Merino,Waldo Jaque,María P
author_facet	Lema,Guillermo Canessa,Roberto Urzúa,Jorge Jalil,Roberto Morán,Sergio Carvajal,Claudia Aeschlimann,Nicolás Merino,Waldo Jaque,María P
author_sort	Lema,Guillermo
title	Función renal en cirugía cardíaca con circulación extracorpórea: Pacientes valvulares y coronarios
title_short	Función renal en cirugía cardíaca con circulación extracorpórea: Pacientes valvulares y coronarios
title_full	Función renal en cirugía cardíaca con circulación extracorpórea: Pacientes valvulares y coronarios
title_fullStr	Función renal en cirugía cardíaca con circulación extracorpórea: Pacientes valvulares y coronarios
title_full_unstemmed	Función renal en cirugía cardíaca con circulación extracorpórea: Pacientes valvulares y coronarios
title_sort	función renal en cirugía cardíaca con circulación extracorpórea: pacientes valvulares y coronarios
publisher	Sociedad Médica de Santiago
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000400006
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Función renal en cirugía cardíaca con circulación extracorpórea: Pacientes valvulares y coronarios

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