Hipertensión arterial resistente

Resistant hypertension, defined as a persistent blood pressure over 140/90 mmHg despite the use of three antihypertensive drugs including a diuretic, is unusual. The diagnosis requires ruling out initially pseudoresistance and a lack of compliance with treatment. Ambulatory blood pressure recording...

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Autor principal: Feldstein,Carlos A
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2008
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000400015
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spelling oai:scielo:S0034-988720080004000152008-06-16Hipertensión arterial resistenteFeldstein,Carlos A Aldosterone antagonists Hypertension Pressoreceptors Resistant hypertension, defined as a persistent blood pressure over 140/90 mmHg despite the use of three antihypertensive drugs including a diuretic, is unusual. The diagnosis requires ruling out initially pseudoresistance and a lack of compliance with treatment. Ambulatory blood pressure recording allow the recognition of white coat hypertension. When there is a clinical or laboratory suspicion, secondary causes of hypertension should be discarded. Excessive salt intake, the presence of concomitant diseases such as diabetes mellitus, chronic renal disease, obesity, and psychiatric conditions such as panic attacks, anxiety and depression, should also be sought. The presence of target organ damage requires a more aggressive treatment of hypertension. Recent clinical studies indicate that the administration of aldosterone antagonists as a fourth therapeutic line provides significant additional blood pressure reduction, when added to previous antihypertensive regimens in subjects with resistant hypertension. The possible blood pressure lowering effects of prolonged electrical activation of carotid baroreceptors is under investigationinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.4 20082008-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000400015es10.4067/S0034-98872008000400015
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Aldosterone antagonists
Hypertension
Pressoreceptors
spellingShingle Aldosterone antagonists
Hypertension
Pressoreceptors
Feldstein,Carlos A
Hipertensión arterial resistente
description Resistant hypertension, defined as a persistent blood pressure over 140/90 mmHg despite the use of three antihypertensive drugs including a diuretic, is unusual. The diagnosis requires ruling out initially pseudoresistance and a lack of compliance with treatment. Ambulatory blood pressure recording allow the recognition of white coat hypertension. When there is a clinical or laboratory suspicion, secondary causes of hypertension should be discarded. Excessive salt intake, the presence of concomitant diseases such as diabetes mellitus, chronic renal disease, obesity, and psychiatric conditions such as panic attacks, anxiety and depression, should also be sought. The presence of target organ damage requires a more aggressive treatment of hypertension. Recent clinical studies indicate that the administration of aldosterone antagonists as a fourth therapeutic line provides significant additional blood pressure reduction, when added to previous antihypertensive regimens in subjects with resistant hypertension. The possible blood pressure lowering effects of prolonged electrical activation of carotid baroreceptors is under investigation
author Feldstein,Carlos A
author_facet Feldstein,Carlos A
author_sort Feldstein,Carlos A
title Hipertensión arterial resistente
title_short Hipertensión arterial resistente
title_full Hipertensión arterial resistente
title_fullStr Hipertensión arterial resistente
title_full_unstemmed Hipertensión arterial resistente
title_sort hipertensión arterial resistente
publisher Sociedad Médica de Santiago
publishDate 2008
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000400015
work_keys_str_mv AT feldsteincarlosa hipertensionarterialresistente
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