Tumores del estroma gastrointestinal (GIST), un particular tipo de neoplasia

Gastrointestinal stromal tumors (GIS) are a heterogeneous group of tumors that express CD 117 molecule in their sur face. They may behave as benign tumors or be highly aggressive. A better survival ofpatients with these tumors has been achieved using the new molecular therapies such as imatinib mesy...

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Detalles Bibliográficos
Autores principales: Bórquez M,Pablo, Neveu C,Rodrigo
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2008
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000700016
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Sumario:Gastrointestinal stromal tumors (GIS) are a heterogeneous group of tumors that express CD 117 molecule in their sur face. They may behave as benign tumors or be highly aggressive. A better survival ofpatients with these tumors has been achieved using the new molecular therapies such as imatinib mesylate, sunitinib and others. This review analyzes the prognostic factors of these tumors, their clinical features and the criteria for malignant behavior. The valué of therapeutic alternatives such as radiotherapy chemotherapy and the new molecular therapies are also discussed