Sobrecrecimiento bacteriano intestinal en pacientes con pancreatitis crónica
Background: Previous reports describe 30-40% of small intestine bacterial overgrowth (SIBO) in patients with chronic pancreatitis (CP), SIBO is a cause of persistent symptoms in this group of patients even when they are treated with pancreatic enzymes. Aim: To asses the frequency of SIBO in patients...
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Sociedad Médica de Santiago
2008
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oai:scielo:S0034-988720080008000032009-01-23Sobrecrecimiento bacteriano intestinal en pacientes con pancreatitis crónicaMancilla A,CarlaMadrid S,Ana MaríaHurtado H,CarmenOrellana B,CarolinaPeña Z,MargaritaTobar A,EduardoBerger F,Zoltán Gastrointestinal contents Malabsorption syndrome Pancreatitis, chronic Background: Previous reports describe 30-40% of small intestine bacterial overgrowth (SIBO) in patients with chronic pancreatitis (CP), SIBO is a cause of persistent symptoms in this group of patients even when they are treated with pancreatic enzymes. Aim: To asses the frequency of SIBO in patients with CP. Patients and methods: We studied 14 patients with CP using an hydrogen breath test with lactulose to detect SIBO, a nonabsorbable carbohydrate, whose results are not influenced by the presence of exocrine insufficiency. Main symptoms and signs were bloating in 9 (64%), recurrent abdominal pain in 8 (57%), intermittent diarrhea in 5 (36%) and steatorrhea in 5 (36%). At the same time we studied a healthy control group paired by age and sex. Results: SIBO was present in 13 of 14 patients with CP (92%) and in 1 of 14 controls (p<0.001). The only patient with CP and without SIBO was recently diagnosed and had minimal morphologic alterations in computed tomography and endoscopic pancreatography Conclusions: SIBO is common in CP and may be responsible for persistent symptoms. Proper diagnosis and treatment could alleviate symptoms andimprove quality of Ufe.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.8 20082008-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000800003es10.4067/S0034-98872008000800003 |
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Scielo Chile |
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Scielo Chile |
language |
Spanish / Castilian |
topic |
Gastrointestinal contents Malabsorption syndrome Pancreatitis, chronic |
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Gastrointestinal contents Malabsorption syndrome Pancreatitis, chronic Mancilla A,Carla Madrid S,Ana María Hurtado H,Carmen Orellana B,Carolina Peña Z,Margarita Tobar A,Eduardo Berger F,Zoltán Sobrecrecimiento bacteriano intestinal en pacientes con pancreatitis crónica |
description |
Background: Previous reports describe 30-40% of small intestine bacterial overgrowth (SIBO) in patients with chronic pancreatitis (CP), SIBO is a cause of persistent symptoms in this group of patients even when they are treated with pancreatic enzymes. Aim: To asses the frequency of SIBO in patients with CP. Patients and methods: We studied 14 patients with CP using an hydrogen breath test with lactulose to detect SIBO, a nonabsorbable carbohydrate, whose results are not influenced by the presence of exocrine insufficiency. Main symptoms and signs were bloating in 9 (64%), recurrent abdominal pain in 8 (57%), intermittent diarrhea in 5 (36%) and steatorrhea in 5 (36%). At the same time we studied a healthy control group paired by age and sex. Results: SIBO was present in 13 of 14 patients with CP (92%) and in 1 of 14 controls (p<0.001). The only patient with CP and without SIBO was recently diagnosed and had minimal morphologic alterations in computed tomography and endoscopic pancreatography Conclusions: SIBO is common in CP and may be responsible for persistent symptoms. Proper diagnosis and treatment could alleviate symptoms andimprove quality of Ufe. |
author |
Mancilla A,Carla Madrid S,Ana María Hurtado H,Carmen Orellana B,Carolina Peña Z,Margarita Tobar A,Eduardo Berger F,Zoltán |
author_facet |
Mancilla A,Carla Madrid S,Ana María Hurtado H,Carmen Orellana B,Carolina Peña Z,Margarita Tobar A,Eduardo Berger F,Zoltán |
author_sort |
Mancilla A,Carla |
title |
Sobrecrecimiento bacteriano intestinal en pacientes con pancreatitis crónica |
title_short |
Sobrecrecimiento bacteriano intestinal en pacientes con pancreatitis crónica |
title_full |
Sobrecrecimiento bacteriano intestinal en pacientes con pancreatitis crónica |
title_fullStr |
Sobrecrecimiento bacteriano intestinal en pacientes con pancreatitis crónica |
title_full_unstemmed |
Sobrecrecimiento bacteriano intestinal en pacientes con pancreatitis crónica |
title_sort |
sobrecrecimiento bacteriano intestinal en pacientes con pancreatitis crónica |
publisher |
Sociedad Médica de Santiago |
publishDate |
2008 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000800003 |
work_keys_str_mv |
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