Carga viral en pacientes pediátricos VIH positivos con terapia antirretroviral

Background: Viral load in pediatric patients with HIV infections can help to make therapeutic decisions to modify the evolution of the disease. Aim: To evaluate viral load in positive HIV children with antiretroviral treatment. Material and methods: Viral load was measured every six months during th...

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Autores principales: Porto-Espinoza,Leticia, Moronta,Reyna, Cuadra-Sánchez,César, Callejas-Valero,Diana, Costa-León,Luciana, Monsalve-Castillo,Francisca, Bernardoni,Cecilia, Estévez,Jesús
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2008
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000800009
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spelling oai:scielo:S0034-988720080008000092009-01-23Carga viral en pacientes pediátricos VIH positivos con terapia antirretroviralPorto-Espinoza,LeticiaMoronta,ReynaCuadra-Sánchez,CésarCallejas-Valero,DianaCosta-León,LucianaMonsalve-Castillo,FranciscaBernardoni,CeciliaEstévez,Jesús Antiretroviral therapy highly active HIV-1 Viral load Background: Viral load in pediatric patients with HIV infections can help to make therapeutic decisions to modify the evolution of the disease. Aim: To evaluate viral load in positive HIV children with antiretroviral treatment. Material and methods: Viral load was measured every six months during three years in fifty pediatric patients chosen randomly in aged 1 to 12 years, using the Test Monitor HIV-1 AMPLICOR, versión 1.5. Results: During the three years follow up, there was an increase in CD4 and CD8 lymphocyte count and decrease in the viral load. However, there was no significant relationship between lymphocyte subpopulation counts and viral loads. Conclusions: Viral load demonstrated to be an appropriate method to quantify plasma HIV-RNA. This tool can help to define the condition of a particular patient to predict clinical course of the disease and to assess the response to the treatment.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.8 20082008-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000800009es10.4067/S0034-98872008000800009
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Antiretroviral therapy highly active
HIV-1
Viral load
spellingShingle Antiretroviral therapy highly active
HIV-1
Viral load
Porto-Espinoza,Leticia
Moronta,Reyna
Cuadra-Sánchez,César
Callejas-Valero,Diana
Costa-León,Luciana
Monsalve-Castillo,Francisca
Bernardoni,Cecilia
Estévez,Jesús
Carga viral en pacientes pediátricos VIH positivos con terapia antirretroviral
description Background: Viral load in pediatric patients with HIV infections can help to make therapeutic decisions to modify the evolution of the disease. Aim: To evaluate viral load in positive HIV children with antiretroviral treatment. Material and methods: Viral load was measured every six months during three years in fifty pediatric patients chosen randomly in aged 1 to 12 years, using the Test Monitor HIV-1 AMPLICOR, versión 1.5. Results: During the three years follow up, there was an increase in CD4 and CD8 lymphocyte count and decrease in the viral load. However, there was no significant relationship between lymphocyte subpopulation counts and viral loads. Conclusions: Viral load demonstrated to be an appropriate method to quantify plasma HIV-RNA. This tool can help to define the condition of a particular patient to predict clinical course of the disease and to assess the response to the treatment.
author Porto-Espinoza,Leticia
Moronta,Reyna
Cuadra-Sánchez,César
Callejas-Valero,Diana
Costa-León,Luciana
Monsalve-Castillo,Francisca
Bernardoni,Cecilia
Estévez,Jesús
author_facet Porto-Espinoza,Leticia
Moronta,Reyna
Cuadra-Sánchez,César
Callejas-Valero,Diana
Costa-León,Luciana
Monsalve-Castillo,Francisca
Bernardoni,Cecilia
Estévez,Jesús
author_sort Porto-Espinoza,Leticia
title Carga viral en pacientes pediátricos VIH positivos con terapia antirretroviral
title_short Carga viral en pacientes pediátricos VIH positivos con terapia antirretroviral
title_full Carga viral en pacientes pediátricos VIH positivos con terapia antirretroviral
title_fullStr Carga viral en pacientes pediátricos VIH positivos con terapia antirretroviral
title_full_unstemmed Carga viral en pacientes pediátricos VIH positivos con terapia antirretroviral
title_sort carga viral en pacientes pediátricos vih positivos con terapia antirretroviral
publisher Sociedad Médica de Santiago
publishDate 2008
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008000800009
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