Valores normales de captación de 131Yodo de 2 y 24 horas

Background: Radiolabeled iodine uptake is a useful tool in the study of thyroid diseases. Aim: To obtain normal values for 131 Iodine thyroid uptake in healthy volunteers. Material and methods: A total of 105 subjects were included (52 males and 53 females), with a mean age of 45 years (range: 20 to...

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Autores principales: González E,Patricio, Carmona C,Alberto R, Araya Q,Verónica, Miranda F,Karina, Massardo V,Teresa, Jiménez R,Beatriz, Jaimovich F,Rodrigo, Gatica R,Héctor
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2008
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001000008
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spelling oai:scielo:S0034-988720080010000082009-01-15Valores normales de captación de 131Yodo de 2 y 24 horasGonzález E,PatricioCarmona C,Alberto RAraya Q,VerónicaMiranda F,KarinaMassardo V,TeresaJiménez R,BeatrizJaimovich F,RodrigoGatica R,Héctor Iodine-131 Iodine radioisotopes Thyroid gland Thyrotropin Background: Radiolabeled iodine uptake is a useful tool in the study of thyroid diseases. Aim: To obtain normal values for 131 Iodine thyroid uptake in healthy volunteers. Material and methods: A total of 105 subjects were included (52 males and 53 females), with a mean age of 45 years (range: 20 to 68, evenly distributed in decades). A questionnaire was applied and a clinical examination was performed to rule out endocrine diseases. Serum TSH and anti-thyroperoxidase antibodies were also measured. The oral 131I dose was 5-10 fiCi, and a Thyrad equipment was used for measurements at 2 and 24 h. Results: Mean global iodine uptake was 5.5%±1.8% (range: 2.3-12.0) at 2 h and 16.2±4.8% (range: 6.5-30.1) at 24 h. The values at 2 h among women and men were 6.0±1.8 and 4.9±1.6%, respectively, (p <0.02). At 24 h, the figures were 17.3±4.5 and 15.0±4.9%, respectively (p =0.01). Compared to their younger counterparts, radioactive iodine uptake was lower among volunteers older than 40 years, at 2 h (5.0±1.7 and 6.0±1.8, respectively, p <0.02) and at 24 h (14.9±4.4 and 17.6±4.9%, respectively, p <0.01). Conclusions: Normal thyroid uptake values in adults are influenced bygender and age. Normal thyroid iodine uptake values are slightly higher in females. Iodine thyroid uptake values decrease slightly in subjects aged more than 40years.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.10 20082008-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001000008es10.4067/S0034-98872008001000008
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Iodine-131
Iodine radioisotopes
Thyroid gland
Thyrotropin
spellingShingle Iodine-131
Iodine radioisotopes
Thyroid gland
Thyrotropin
González E,Patricio
Carmona C,Alberto R
Araya Q,Verónica
Miranda F,Karina
Massardo V,Teresa
Jiménez R,Beatriz
Jaimovich F,Rodrigo
Gatica R,Héctor
Valores normales de captación de 131Yodo de 2 y 24 horas
description Background: Radiolabeled iodine uptake is a useful tool in the study of thyroid diseases. Aim: To obtain normal values for 131 Iodine thyroid uptake in healthy volunteers. Material and methods: A total of 105 subjects were included (52 males and 53 females), with a mean age of 45 years (range: 20 to 68, evenly distributed in decades). A questionnaire was applied and a clinical examination was performed to rule out endocrine diseases. Serum TSH and anti-thyroperoxidase antibodies were also measured. The oral 131I dose was 5-10 fiCi, and a Thyrad equipment was used for measurements at 2 and 24 h. Results: Mean global iodine uptake was 5.5%±1.8% (range: 2.3-12.0) at 2 h and 16.2±4.8% (range: 6.5-30.1) at 24 h. The values at 2 h among women and men were 6.0±1.8 and 4.9±1.6%, respectively, (p <0.02). At 24 h, the figures were 17.3±4.5 and 15.0±4.9%, respectively (p =0.01). Compared to their younger counterparts, radioactive iodine uptake was lower among volunteers older than 40 years, at 2 h (5.0±1.7 and 6.0±1.8, respectively, p <0.02) and at 24 h (14.9±4.4 and 17.6±4.9%, respectively, p <0.01). Conclusions: Normal thyroid uptake values in adults are influenced bygender and age. Normal thyroid iodine uptake values are slightly higher in females. Iodine thyroid uptake values decrease slightly in subjects aged more than 40years.
author González E,Patricio
Carmona C,Alberto R
Araya Q,Verónica
Miranda F,Karina
Massardo V,Teresa
Jiménez R,Beatriz
Jaimovich F,Rodrigo
Gatica R,Héctor
author_facet González E,Patricio
Carmona C,Alberto R
Araya Q,Verónica
Miranda F,Karina
Massardo V,Teresa
Jiménez R,Beatriz
Jaimovich F,Rodrigo
Gatica R,Héctor
author_sort González E,Patricio
title Valores normales de captación de 131Yodo de 2 y 24 horas
title_short Valores normales de captación de 131Yodo de 2 y 24 horas
title_full Valores normales de captación de 131Yodo de 2 y 24 horas
title_fullStr Valores normales de captación de 131Yodo de 2 y 24 horas
title_full_unstemmed Valores normales de captación de 131Yodo de 2 y 24 horas
title_sort valores normales de captación de 131yodo de 2 y 24 horas
publisher Sociedad Médica de Santiago
publishDate 2008
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001000008
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