Hiperparatiroidismo primario en el adolescente: Caso clínico

We report a 13 year-old mate with a history of multiple fractures and kidney stones. The laboratory showed a hypercalcemia of 11.5 mg/dl, a PTH of 112.6 pg/ml and 24 hour urinary calcium of 571 mg. Bone densitometry showed spine and fémur Z scores of -2.9 and -1.6, respectively, kidney ultrasound sh...

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Autores principales:	Salman M,Patricio, González V,Gilberto, Grant del R,Carlos, González D,Hernán, Arteaga U,Eugenio
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2008
Materias:	Hyperparathyroidism primary Multiple endocrine neoplasia Nephrocalcinosis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001000010
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spelling	oai:scielo:S0034-988720080010000102009-01-15Hiperparatiroidismo primario en el adolescente: Caso clínicoSalman M,PatricioGonzález V,GilbertoGrant del R,CarlosGonzález D,HernánArteaga U,Eugenio Hyperparathyroidism primary Multiple endocrine neoplasia Nephrocalcinosis We report a 13 year-old mate with a history of multiple fractures and kidney stones. The laboratory showed a hypercalcemia of 11.5 mg/dl, a PTH of 112.6 pg/ml and 24 hour urinary calcium of 571 mg. Bone densitometry showed spine and fémur Z scores of -2.9 and -1.6, respectively, kidney ultrasound showed nephrocalcinosis and a MIBI-SPECT scintigram showed a higher uptake in the ríght lower parathyroid gland. The diagnosis of primary hyperparathyroidism was made and the patient was operated, excising the ríght lower parathyroid gland. After surgery, serum calcium and PTH levels returned to normal values. In children, the proportion of cases with parathyroid hyperplasia is higher than in adults. Therefore, during surgery all four parathyroid glands must be explored. There is also a higher frequency of ectopic adenomas. Family history must be explored to discard the presence of a multiple endocrine neoplasia (MEN I or II), a familial hyperparathyroidism or a syndrome of primary hyperparathyroidism associated to mandibular tumor.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.10 20082008-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001000010es10.4067/S0034-98872008001000010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Hyperparathyroidism primary Multiple endocrine neoplasia Nephrocalcinosis
spellingShingle	Hyperparathyroidism primary Multiple endocrine neoplasia Nephrocalcinosis Salman M,Patricio González V,Gilberto Grant del R,Carlos González D,Hernán Arteaga U,Eugenio Hiperparatiroidismo primario en el adolescente: Caso clínico
description	We report a 13 year-old mate with a history of multiple fractures and kidney stones. The laboratory showed a hypercalcemia of 11.5 mg/dl, a PTH of 112.6 pg/ml and 24 hour urinary calcium of 571 mg. Bone densitometry showed spine and fémur Z scores of -2.9 and -1.6, respectively, kidney ultrasound showed nephrocalcinosis and a MIBI-SPECT scintigram showed a higher uptake in the ríght lower parathyroid gland. The diagnosis of primary hyperparathyroidism was made and the patient was operated, excising the ríght lower parathyroid gland. After surgery, serum calcium and PTH levels returned to normal values. In children, the proportion of cases with parathyroid hyperplasia is higher than in adults. Therefore, during surgery all four parathyroid glands must be explored. There is also a higher frequency of ectopic adenomas. Family history must be explored to discard the presence of a multiple endocrine neoplasia (MEN I or II), a familial hyperparathyroidism or a syndrome of primary hyperparathyroidism associated to mandibular tumor.
author	Salman M,Patricio González V,Gilberto Grant del R,Carlos González D,Hernán Arteaga U,Eugenio
author_facet	Salman M,Patricio González V,Gilberto Grant del R,Carlos González D,Hernán Arteaga U,Eugenio
author_sort	Salman M,Patricio
title	Hiperparatiroidismo primario en el adolescente: Caso clínico
title_short	Hiperparatiroidismo primario en el adolescente: Caso clínico
title_full	Hiperparatiroidismo primario en el adolescente: Caso clínico
title_fullStr	Hiperparatiroidismo primario en el adolescente: Caso clínico
title_full_unstemmed	Hiperparatiroidismo primario en el adolescente: Caso clínico
title_sort	hiperparatiroidismo primario en el adolescente: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001000010
work_keys_str_mv	AT salmanmpatricio hiperparatiroidismoprimarioeneladolescentecasoclinico AT gonzalezvgilberto hiperparatiroidismoprimarioeneladolescentecasoclinico AT grantdelrcarlos hiperparatiroidismoprimarioeneladolescentecasoclinico AT gonzalezdhernan hiperparatiroidismoprimarioeneladolescentecasoclinico AT arteagaueugenio hiperparatiroidismoprimarioeneladolescentecasoclinico
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Hiperparatiroidismo primario en el adolescente: Caso clínico

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