Diagnóstico y tratamiento de las metástasis encefálicas

Cerebral metastasis occur in 20 to 30 percent of patients with systemic cancer and are the most common type of intracranial tumor. The median survival of untreated patients is one month with a slightly longer survival in those treated with steroids. Patients treated with whole brain radiation therap...

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Autores principales:	Sajama,Carlos, Lorenzoni,José, Tagle,Patricio
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2008
Materias:	Brain neoplasm Cranial irradiation Neoplasm metastasis Radiosurgery
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001000014
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spelling	oai:scielo:S0034-988720080010000142009-01-15Diagnóstico y tratamiento de las metástasis encefálicasSajama,CarlosLorenzoni,JoséTagle,Patricio Brain neoplasm Cranial irradiation Neoplasm metastasis Radiosurgery Cerebral metastasis occur in 20 to 30 percent of patients with systemic cancer and are the most common type of intracranial tumor. The median survival of untreated patients is one month with a slightly longer survival in those treated with steroids. Patients treated with whole brain radiation therapy survive between 3 to 6 months. In selected cases survival can increase to 10 to 12 months with combination of surgery and radiotherapy or stereotactic radiosurgery alone or associated to radiotherapy. Most brain metástasis arise from lung, breast and melanomas. The most important criteria for selecting patients who will benefit from surgery or stereotactic radiosurgery are a Karnofsky score of 70 or more, systemic control of the cancer and absence of leptomeningeal involvement. Surgery is indicated in patients with a single lesion located in an accessible zone and stereotactic radiosurgery is indicated for lesions up to 3 cm of diameter, and in patients with up to 3 or 4 metastasis, no matter their location. The survival benefit of chemotherapy in brain metastasis has not been demonstrated.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.10 20082008-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001000014es10.4067/S0034-98872008001000014
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Brain neoplasm Cranial irradiation Neoplasm metastasis Radiosurgery
spellingShingle	Brain neoplasm Cranial irradiation Neoplasm metastasis Radiosurgery Sajama,Carlos Lorenzoni,José Tagle,Patricio Diagnóstico y tratamiento de las metástasis encefálicas
description	Cerebral metastasis occur in 20 to 30 percent of patients with systemic cancer and are the most common type of intracranial tumor. The median survival of untreated patients is one month with a slightly longer survival in those treated with steroids. Patients treated with whole brain radiation therapy survive between 3 to 6 months. In selected cases survival can increase to 10 to 12 months with combination of surgery and radiotherapy or stereotactic radiosurgery alone or associated to radiotherapy. Most brain metástasis arise from lung, breast and melanomas. The most important criteria for selecting patients who will benefit from surgery or stereotactic radiosurgery are a Karnofsky score of 70 or more, systemic control of the cancer and absence of leptomeningeal involvement. Surgery is indicated in patients with a single lesion located in an accessible zone and stereotactic radiosurgery is indicated for lesions up to 3 cm of diameter, and in patients with up to 3 or 4 metastasis, no matter their location. The survival benefit of chemotherapy in brain metastasis has not been demonstrated.
author	Sajama,Carlos Lorenzoni,José Tagle,Patricio
author_facet	Sajama,Carlos Lorenzoni,José Tagle,Patricio
author_sort	Sajama,Carlos
title	Diagnóstico y tratamiento de las metástasis encefálicas
title_short	Diagnóstico y tratamiento de las metástasis encefálicas
title_full	Diagnóstico y tratamiento de las metástasis encefálicas
title_fullStr	Diagnóstico y tratamiento de las metástasis encefálicas
title_full_unstemmed	Diagnóstico y tratamiento de las metástasis encefálicas
title_sort	diagnóstico y tratamiento de las metástasis encefálicas
publisher	Sociedad Médica de Santiago
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001000014
work_keys_str_mv	AT sajamacarlos diagnosticoytratamientodelasmetastasisencefalicas AT lorenzonijose diagnosticoytratamientodelasmetastasisencefalicas AT taglepatricio diagnosticoytratamientodelasmetastasisencefalicas
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Diagnóstico y tratamiento de las metástasis encefálicas

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