Virus papiloma humano y cáncer cérvico-uterino

Molecular, clinical and epidemiolagical studies have established beyond doubt that human papiloma viruses (HPV) cause cervical cancer. The virus is also associated with genital warts and other less common cancers in oropharynx, vulva, vagina and penis. Worldwide, VPH genotypes 16 and 18 are the most...

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Autores principales:	O'Ryan G,Miguel, Valenzuela,María Teresa
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2008
Materias:	Human papilloma virus Oncogenic viruses Uterine cervical neoplasms
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001100001
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spelling	oai:scielo:S0034-988720080011000012009-03-23Virus papiloma humano y cáncer cérvico-uterinoO'Ryan G,MiguelValenzuela,María Teresa Human papilloma virus Oncogenic viruses Uterine cervical neoplasms Molecular, clinical and epidemiolagical studies have established beyond doubt that human papiloma viruses (HPV) cause cervical cancer. The virus is also associated with genital warts and other less common cancers in oropharynx, vulva, vagina and penis. Worldwide, VPH genotypes 16 and 18 are the most common high risk genotypes, detected in near 70% of women with cervical cáncer. The discovery of a cause-effect relationship between several carcinogenic microorganisms and cancer open avenues for new diagnostic, treatment and prevention strategies. In this issue of Revista Médica de Chile, two papers on HPV are presented. Guzman and colleagues demonstrate that HPV can be detected in 66% to 77% of healthy male adolescents by polymerase chain reaction and that positivity depends on the site of the penis that is sampled. These results support the role of male to female transmission of high risk HPVs in Chile and should lead to even more active educational campaigns. The second paper provides recommendations for HPV vaccine use in Chile, generated by the Immunization Advisory Committee of the Chilean Infectious Disease Society. To issue these recommendations, the Committee analyzes the epidemiological information available on HPV infection and cervical cancer in Chile, vaccine safety and effectiveness data, and describes cost-effectiveness studies. Taking into account that universal vaccination is controversial the Committee favors vaccine use in Chile and it's incorporation into a national program. However, there is an indication that the country requires the implementation of an integrated surveillance approach including cross matching of data obtained from HPV genotype surveillance, monitoring of vaccination coverage, and surveillance of cervical cáncer The final decision of universal vaccine use in Chile should be based on a through analysis of information.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.136 n.11 20082008-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001100001es10.4067/S0034-98872008001100001
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Human papilloma virus Oncogenic viruses Uterine cervical neoplasms
spellingShingle	Human papilloma virus Oncogenic viruses Uterine cervical neoplasms O'Ryan G,Miguel Valenzuela,María Teresa Virus papiloma humano y cáncer cérvico-uterino
description	Molecular, clinical and epidemiolagical studies have established beyond doubt that human papiloma viruses (HPV) cause cervical cancer. The virus is also associated with genital warts and other less common cancers in oropharynx, vulva, vagina and penis. Worldwide, VPH genotypes 16 and 18 are the most common high risk genotypes, detected in near 70% of women with cervical cáncer. The discovery of a cause-effect relationship between several carcinogenic microorganisms and cancer open avenues for new diagnostic, treatment and prevention strategies. In this issue of Revista Médica de Chile, two papers on HPV are presented. Guzman and colleagues demonstrate that HPV can be detected in 66% to 77% of healthy male adolescents by polymerase chain reaction and that positivity depends on the site of the penis that is sampled. These results support the role of male to female transmission of high risk HPVs in Chile and should lead to even more active educational campaigns. The second paper provides recommendations for HPV vaccine use in Chile, generated by the Immunization Advisory Committee of the Chilean Infectious Disease Society. To issue these recommendations, the Committee analyzes the epidemiological information available on HPV infection and cervical cancer in Chile, vaccine safety and effectiveness data, and describes cost-effectiveness studies. Taking into account that universal vaccination is controversial the Committee favors vaccine use in Chile and it's incorporation into a national program. However, there is an indication that the country requires the implementation of an integrated surveillance approach including cross matching of data obtained from HPV genotype surveillance, monitoring of vaccination coverage, and surveillance of cervical cáncer The final decision of universal vaccine use in Chile should be based on a through analysis of information.
author	O'Ryan G,Miguel Valenzuela,María Teresa
author_facet	O'Ryan G,Miguel Valenzuela,María Teresa
author_sort	O'Ryan G,Miguel
title	Virus papiloma humano y cáncer cérvico-uterino
title_short	Virus papiloma humano y cáncer cérvico-uterino
title_full	Virus papiloma humano y cáncer cérvico-uterino
title_fullStr	Virus papiloma humano y cáncer cérvico-uterino
title_full_unstemmed	Virus papiloma humano y cáncer cérvico-uterino
title_sort	virus papiloma humano y cáncer cérvico-uterino
publisher	Sociedad Médica de Santiago
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872008001100001
work_keys_str_mv	AT oryangmiguel viruspapilomahumanoycancercervicouterino AT valenzuelamariateresa viruspapilomahumanoycancercervicouterino
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Virus papiloma humano y cáncer cérvico-uterino

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