Pubarquia precoz: Experience in 173 cases

Background: Precocious pubarche (PP), defined as the development of sexual pubic hair before 8 years of age in females and before 9 years in males, is usually a benign condition but it can also be the first sign of an underlying disease. Aim: To analyze the etiology and perform a short term follow u...

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Autores principales:	Eyzaguirre,Francisca C, Bancalari,Rodrigo, Youlton,Ronald, Román,Rossana, Silva,Ricardo, García,Hernán, Mericq,Verónica
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2009
Materias:	Adrenarche Pubarche, precocious Puberty
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000100005
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spelling	oai:scielo:S0034-988720090001000052009-04-13Pubarquia precoz: Experience in 173 casesEyzaguirre,Francisca CBancalari,RodrigoYoulton,RonaldRomán,RossanaSilva,RicardoGarcía,HernánMericq,Verónica Adrenarche Pubarche, precocious Puberty Background: Precocious pubarche (PP), defined as the development of sexual pubic hair before 8 years of age in females and before 9 years in males, is usually a benign condition but it can also be the first sign of an underlying disease. Aim: To analyze the etiology and perform a short term follow up in a cohort ofpatients with PP. Material and methods: A group of 173patients (158 females) consulted for PP with a mean age of 7.4+0.1 years. These patients were followed between 15 to 60 months. Anthropometric measurements, bone age, serum levels of total testosterone, 17 OH progesterone (17 OHP) and dehydroepiandrosterone sulphate (DHEAS) were evaluated. Results: Mean birth weight and length was 3024.1+50.5 g and 48.5+0.3 cm, respectively. Ten percent of children were small for gestational age at birth. Bone age was accelerated by 1.1+0.01 years. One hundred and twelve patients were classified as having idiopathic PP (64.7%; 105 females), 29 as central precocious puberty (16.8%; only females), 16 as exaggerated adrenarche (EA 9.2%; 13 females) and 16 as non classical adrenal hyperplasia (9.2%; 11 females). Conclusions: PP represents a common and usually benign sign. However, 26% of cases had a pathologic underlying condition. Therefore, all children with PP should be evaluated by a pediatric endocrinologist. Low birth weight was not frequent in this cohort and these patients did not show EA .info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.1 20092009-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000100005es10.4067/S0034-98872009000100005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Adrenarche Pubarche, precocious Puberty
spellingShingle	Adrenarche Pubarche, precocious Puberty Eyzaguirre,Francisca C Bancalari,Rodrigo Youlton,Ronald Román,Rossana Silva,Ricardo García,Hernán Mericq,Verónica Pubarquia precoz: Experience in 173 cases
description	Background: Precocious pubarche (PP), defined as the development of sexual pubic hair before 8 years of age in females and before 9 years in males, is usually a benign condition but it can also be the first sign of an underlying disease. Aim: To analyze the etiology and perform a short term follow up in a cohort ofpatients with PP. Material and methods: A group of 173patients (158 females) consulted for PP with a mean age of 7.4+0.1 years. These patients were followed between 15 to 60 months. Anthropometric measurements, bone age, serum levels of total testosterone, 17 OH progesterone (17 OHP) and dehydroepiandrosterone sulphate (DHEAS) were evaluated. Results: Mean birth weight and length was 3024.1+50.5 g and 48.5+0.3 cm, respectively. Ten percent of children were small for gestational age at birth. Bone age was accelerated by 1.1+0.01 years. One hundred and twelve patients were classified as having idiopathic PP (64.7%; 105 females), 29 as central precocious puberty (16.8%; only females), 16 as exaggerated adrenarche (EA 9.2%; 13 females) and 16 as non classical adrenal hyperplasia (9.2%; 11 females). Conclusions: PP represents a common and usually benign sign. However, 26% of cases had a pathologic underlying condition. Therefore, all children with PP should be evaluated by a pediatric endocrinologist. Low birth weight was not frequent in this cohort and these patients did not show EA .
author	Eyzaguirre,Francisca C Bancalari,Rodrigo Youlton,Ronald Román,Rossana Silva,Ricardo García,Hernán Mericq,Verónica
author_facet	Eyzaguirre,Francisca C Bancalari,Rodrigo Youlton,Ronald Román,Rossana Silva,Ricardo García,Hernán Mericq,Verónica
author_sort	Eyzaguirre,Francisca C
title	Pubarquia precoz: Experience in 173 cases
title_short	Pubarquia precoz: Experience in 173 cases
title_full	Pubarquia precoz: Experience in 173 cases
title_fullStr	Pubarquia precoz: Experience in 173 cases
title_full_unstemmed	Pubarquia precoz: Experience in 173 cases
title_sort	pubarquia precoz: experience in 173 cases
publisher	Sociedad Médica de Santiago
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000100005
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Pubarquia precoz: Experience in 173 cases

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