Biología del envejecimiento

The study of biological aging has seen a spectacularly fast progress in the last decade. Besides a better understanding and comprehension of physiological aspects, an important advance has been the identification of at least a hundred different genes which control the process of aging. Their mechani...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Pérez,Viviana, Sierra,Felipe
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2009
Materias:
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000200017
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:scielo:S0034-98872009000200017
record_format dspace
spelling oai:scielo:S0034-988720090002000172009-06-10Biología del envejecimientoPérez,VivianaSierra,Felipe Aging Genes Stem cells The study of biological aging has seen a spectacularly fast progress in the last decade. Besides a better understanding and comprehension of physiological aspects, an important advance has been the identification of at least a hundred different genes which control the process of aging. Their mechanism of action falls within the expectations from a handful of theories  which attempt to provide a global explanation of the phenomenon of aging, including free radicals, cell senescence and loss of regenerative capacity through the activation of stem cells. In this review we will concentrate in these biological aspects, with a special emphasis on animal models used to study both the genetics and physiology of aging as well as experimental approaches to test the aforementioned theories. It should be emphasized that, while the emphasis is in purely biological aspects of the process, the fast pace of aging of the world's population, including Chile, needs a rapid advance also in our understanding o fits social and economic implications.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.2 20092009-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000200017es10.4067/S0034-98872009000200017
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Aging
Genes
Stem cells
spellingShingle Aging
Genes
Stem cells
Pérez,Viviana
Sierra,Felipe
Biología del envejecimiento
description The study of biological aging has seen a spectacularly fast progress in the last decade. Besides a better understanding and comprehension of physiological aspects, an important advance has been the identification of at least a hundred different genes which control the process of aging. Their mechanism of action falls within the expectations from a handful of theories  which attempt to provide a global explanation of the phenomenon of aging, including free radicals, cell senescence and loss of regenerative capacity through the activation of stem cells. In this review we will concentrate in these biological aspects, with a special emphasis on animal models used to study both the genetics and physiology of aging as well as experimental approaches to test the aforementioned theories. It should be emphasized that, while the emphasis is in purely biological aspects of the process, the fast pace of aging of the world's population, including Chile, needs a rapid advance also in our understanding o fits social and economic implications.
author Pérez,Viviana
Sierra,Felipe
author_facet Pérez,Viviana
Sierra,Felipe
author_sort Pérez,Viviana
title Biología del envejecimiento
title_short Biología del envejecimiento
title_full Biología del envejecimiento
title_fullStr Biología del envejecimiento
title_full_unstemmed Biología del envejecimiento
title_sort biología del envejecimiento
publisher Sociedad Médica de Santiago
publishDate 2009
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000200017
work_keys_str_mv AT perezviviana biologiadelenvejecimiento
AT sierrafelipe biologiadelenvejecimiento
_version_ 1718436429550321664