Trastorno linfoproliferativo post trasplante renal en un niño

Post transplant lymphoproliferative disorder (PTLD) is the commonest form of post transplant malignancy in children. The incidence in renal transplant recipients varies between 2%-4%. They are characterized by uncontrolled B lymphocyte proliferation, in most cases driven by Epstein Barr virus (EBV)....

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Autores principales:	Márquez U,Sonia, Peredo G,María Soledad, Vogel S,Andrea, Ibáñez A,Paulina
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2009
Materias:	Immunosuppression Kidney transplantation Lymphoproliferative disorders
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000300013
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spelling	oai:scielo:S0034-988720090003000132009-06-15Trastorno linfoproliferativo post trasplante renal en un niñoMárquez U,SoniaPeredo G,María SoledadVogel S,AndreaIbáñez A,Paulina Immunosuppression Kidney transplantation Lymphoproliferative disorders Post transplant lymphoproliferative disorder (PTLD) is the commonest form of post transplant malignancy in children. The incidence in renal transplant recipients varies between 2%-4%. They are characterized by uncontrolled B lymphocyte proliferation, in most cases driven by Epstein Barr virus (EBV). They are more common in younger children, EBV seronegative patients and those who receive aggressive immunosuppression. PTLD commonly presents in an unspecific form and it requires high suspicion rate for its diagnosis, especially in children with risk factors. We report a twelve year-old girl who developed fever, sore throat and lymph node enlargement, six months after receiving a renal allograft. Laboratory assessment and imaging studies were compatible with PTLD, which was confirmed by biopsy. Treatment was reduction of immunosuppression and surveillance. The patient had a favorable evolution.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.3 20092009-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000300013es10.4067/S0034-98872009000300013
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Immunosuppression Kidney transplantation Lymphoproliferative disorders
spellingShingle	Immunosuppression Kidney transplantation Lymphoproliferative disorders Márquez U,Sonia Peredo G,María Soledad Vogel S,Andrea Ibáñez A,Paulina Trastorno linfoproliferativo post trasplante renal en un niño
description	Post transplant lymphoproliferative disorder (PTLD) is the commonest form of post transplant malignancy in children. The incidence in renal transplant recipients varies between 2%-4%. They are characterized by uncontrolled B lymphocyte proliferation, in most cases driven by Epstein Barr virus (EBV). They are more common in younger children, EBV seronegative patients and those who receive aggressive immunosuppression. PTLD commonly presents in an unspecific form and it requires high suspicion rate for its diagnosis, especially in children with risk factors. We report a twelve year-old girl who developed fever, sore throat and lymph node enlargement, six months after receiving a renal allograft. Laboratory assessment and imaging studies were compatible with PTLD, which was confirmed by biopsy. Treatment was reduction of immunosuppression and surveillance. The patient had a favorable evolution.
author	Márquez U,Sonia Peredo G,María Soledad Vogel S,Andrea Ibáñez A,Paulina
author_facet	Márquez U,Sonia Peredo G,María Soledad Vogel S,Andrea Ibáñez A,Paulina
author_sort	Márquez U,Sonia
title	Trastorno linfoproliferativo post trasplante renal en un niño
title_short	Trastorno linfoproliferativo post trasplante renal en un niño
title_full	Trastorno linfoproliferativo post trasplante renal en un niño
title_fullStr	Trastorno linfoproliferativo post trasplante renal en un niño
title_full_unstemmed	Trastorno linfoproliferativo post trasplante renal en un niño
title_sort	trastorno linfoproliferativo post trasplante renal en un niño
publisher	Sociedad Médica de Santiago
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000300013
work_keys_str_mv	AT marquezusonia trastornolinfoproliferativoposttrasplanterenalenunnino AT peredogmariasoledad trastornolinfoproliferativoposttrasplanterenalenunnino AT vogelsandrea trastornolinfoproliferativoposttrasplanterenalenunnino AT ibanezapaulina trastornolinfoproliferativoposttrasplanterenalenunnino
_version_	1718436433944903680

Trastorno linfoproliferativo post trasplante renal en un niño

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