Resultados del tratamiento quirúrgico de las metástasis hepáticas por cáncer colorrectal
Background: Surgical resection is the only treatment associated with long-term cure in patients with liver metastasis from colorectal cancer, achieving a 30% to 40% five years survival. Aim: To evaluate the results of liver resection for metastatic colorectal cancer in our centre. Patients and metho...
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Sociedad Médica de Santiago
2009
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oai:scielo:S0034-988720090004000062009-06-25Resultados del tratamiento quirúrgico de las metástasis hepáticas por cáncer colorrectalNorero,EnriqueJarufe,NicolásButte,Jean MNorero,BlancaDuarte,IgnacioTorres,JavieraPinedo,GeorgeLópez,FranciscoGuerra,Juan FranciscoIbáñez,LuisZúñiga,ÁlvaroGuzmán,SergioMartínez,Jorge Colorectal neoplasms Neoplasm metastasis Survival Background: Surgical resection is the only treatment associated with long-term cure in patients with liver metastasis from colorectal cancer, achieving a 30% to 40% five years survival. Aim: To evaluate the results of liver resection for metastatic colorectal cancer in our centre. Patients and methods: Retrospective study. Epidemiological, perioperative and follow up data of patients undergoing liver resection for metastatic colorectal cancer between January 1990 and July 2007 were assessed. We compared the results between two periods; period 1 (1990-1997) and period 2 (1998-2007). Results: Sixty six patients aged 61± 12 years (46 males) underwent 75 resections. An anatomical excision was performed in 54 (72%) cases, a right hepatectomy in 18, an extended right hepatectomy in 11, a left hepatectomy in 1, and a segmentectomy in 24. In 24 (32%) patients the liver resection was simultaneous with the colorectal cancer resection. Operative time was 221±86 min. Hospital stay was 11±5 days. Postoperative morbidity was 35% and surgical mortality was 0%. Resection margin was free of tumor in 53 (80%) patients. Five years overall and hepatic disease-free survival was 38% and 23%, respectively. In period 2, more anatomical resections than in period 1 were performed (77% and 55%, respectively, p =0.04), without an increase in complications (35% and 34%, respectively; p =ns), but with a better five years survival (45% and 21 %, respectively, p =0.04). Conclusions: Five years survival for excision of liver metastatic colorectal cancer in our center is similar to that reported abroad. During the second period there has been a trend toward more extensive resections which was associated with a better survival, without an increase in complications or mortality .info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.4 20092009-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000400006es10.4067/S0034-98872009000400006 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
Spanish / Castilian |
| topic |
Colorectal neoplasms Neoplasm metastasis Survival |
| spellingShingle |
Colorectal neoplasms Neoplasm metastasis Survival Norero,Enrique Jarufe,Nicolás Butte,Jean M Norero,Blanca Duarte,Ignacio Torres,Javiera Pinedo,George López,Francisco Guerra,Juan Francisco Ibáñez,Luis Zúñiga,Álvaro Guzmán,Sergio Martínez,Jorge Resultados del tratamiento quirúrgico de las metástasis hepáticas por cáncer colorrectal |
| description |
Background: Surgical resection is the only treatment associated with long-term cure in patients with liver metastasis from colorectal cancer, achieving a 30% to 40% five years survival. Aim: To evaluate the results of liver resection for metastatic colorectal cancer in our centre. Patients and methods: Retrospective study. Epidemiological, perioperative and follow up data of patients undergoing liver resection for metastatic colorectal cancer between January 1990 and July 2007 were assessed. We compared the results between two periods; period 1 (1990-1997) and period 2 (1998-2007). Results: Sixty six patients aged 61± 12 years (46 males) underwent 75 resections. An anatomical excision was performed in 54 (72%) cases, a right hepatectomy in 18, an extended right hepatectomy in 11, a left hepatectomy in 1, and a segmentectomy in 24. In 24 (32%) patients the liver resection was simultaneous with the colorectal cancer resection. Operative time was 221±86 min. Hospital stay was 11±5 days. Postoperative morbidity was 35% and surgical mortality was 0%. Resection margin was free of tumor in 53 (80%) patients. Five years overall and hepatic disease-free survival was 38% and 23%, respectively. In period 2, more anatomical resections than in period 1 were performed (77% and 55%, respectively, p =0.04), without an increase in complications (35% and 34%, respectively; p =ns), but with a better five years survival (45% and 21 %, respectively, p =0.04). Conclusions: Five years survival for excision of liver metastatic colorectal cancer in our center is similar to that reported abroad. During the second period there has been a trend toward more extensive resections which was associated with a better survival, without an increase in complications or mortality . |
| author |
Norero,Enrique Jarufe,Nicolás Butte,Jean M Norero,Blanca Duarte,Ignacio Torres,Javiera Pinedo,George López,Francisco Guerra,Juan Francisco Ibáñez,Luis Zúñiga,Álvaro Guzmán,Sergio Martínez,Jorge |
| author_facet |
Norero,Enrique Jarufe,Nicolás Butte,Jean M Norero,Blanca Duarte,Ignacio Torres,Javiera Pinedo,George López,Francisco Guerra,Juan Francisco Ibáñez,Luis Zúñiga,Álvaro Guzmán,Sergio Martínez,Jorge |
| author_sort |
Norero,Enrique |
| title |
Resultados del tratamiento quirúrgico de las metástasis hepáticas por cáncer colorrectal |
| title_short |
Resultados del tratamiento quirúrgico de las metástasis hepáticas por cáncer colorrectal |
| title_full |
Resultados del tratamiento quirúrgico de las metástasis hepáticas por cáncer colorrectal |
| title_fullStr |
Resultados del tratamiento quirúrgico de las metástasis hepáticas por cáncer colorrectal |
| title_full_unstemmed |
Resultados del tratamiento quirúrgico de las metástasis hepáticas por cáncer colorrectal |
| title_sort |
resultados del tratamiento quirúrgico de las metástasis hepáticas por cáncer colorrectal |
| publisher |
Sociedad Médica de Santiago |
| publishDate |
2009 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000400006 |
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