Telangiectasia hemorrágica hereditaria: Tratamiento farmacológico

Hereditary hemorrhagic telangiectasia (HHT) of Rendu-Osler-Weber disease is a multi system vascular dysplasia characterized by the presence of multiple telangiectasias, mainly affecting mucosal tissue and arterial-venous connections. It commonly affects lungs, liver and central nervous system. Bleed...

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Autores principales:	Molinos-Castro,Sonia, Pesqueira-Fontán,Paula María, Díaz-Peromingo,José Antonio
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2009
Materias:	Blood transfusions Fibrinolysis Telangiectasia, hereditary hemorrhagic
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000500015
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spelling	oai:scielo:S0034-988720090005000152009-07-17Telangiectasia hemorrágica hereditaria: Tratamiento farmacológicoMolinos-Castro,SoniaPesqueira-Fontán,Paula MaríaDíaz-Peromingo,José Antonio Blood transfusions Fibrinolysis Telangiectasia, hereditary hemorrhagic Hereditary hemorrhagic telangiectasia (HHT) of Rendu-Osler-Weber disease is a multi system vascular dysplasia characterized by the presence of multiple telangiectasias, mainly affecting mucosal tissue and arterial-venous connections. It commonly affects lungs, liver and central nervous system. Bleeding is the most common symptom and its treatment can be surgical or pharmacological. We herein review the systemic therapy that attempts to minimize bleeding as well as blood transfusion therapy. Blood therapy and fibrinolytic treatment especially aminocaproic acid and tranexamic acid are discussed. Danazol, hormone therapy and other less common drugs used in the treatment of HHT are also reviewed.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.5 20092009-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000500015es10.4067/S0034-98872009000500015
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Blood transfusions Fibrinolysis Telangiectasia, hereditary hemorrhagic
spellingShingle	Blood transfusions Fibrinolysis Telangiectasia, hereditary hemorrhagic Molinos-Castro,Sonia Pesqueira-Fontán,Paula María Díaz-Peromingo,José Antonio Telangiectasia hemorrágica hereditaria: Tratamiento farmacológico
description	Hereditary hemorrhagic telangiectasia (HHT) of Rendu-Osler-Weber disease is a multi system vascular dysplasia characterized by the presence of multiple telangiectasias, mainly affecting mucosal tissue and arterial-venous connections. It commonly affects lungs, liver and central nervous system. Bleeding is the most common symptom and its treatment can be surgical or pharmacological. We herein review the systemic therapy that attempts to minimize bleeding as well as blood transfusion therapy. Blood therapy and fibrinolytic treatment especially aminocaproic acid and tranexamic acid are discussed. Danazol, hormone therapy and other less common drugs used in the treatment of HHT are also reviewed.
author	Molinos-Castro,Sonia Pesqueira-Fontán,Paula María Díaz-Peromingo,José Antonio
author_facet	Molinos-Castro,Sonia Pesqueira-Fontán,Paula María Díaz-Peromingo,José Antonio
author_sort	Molinos-Castro,Sonia
title	Telangiectasia hemorrágica hereditaria: Tratamiento farmacológico
title_short	Telangiectasia hemorrágica hereditaria: Tratamiento farmacológico
title_full	Telangiectasia hemorrágica hereditaria: Tratamiento farmacológico
title_fullStr	Telangiectasia hemorrágica hereditaria: Tratamiento farmacológico
title_full_unstemmed	Telangiectasia hemorrágica hereditaria: Tratamiento farmacológico
title_sort	telangiectasia hemorrágica hereditaria: tratamiento farmacológico
publisher	Sociedad Médica de Santiago
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000500015
work_keys_str_mv	AT molinoscastrosonia telangiectasiahemorragicahereditariatratamientofarmacologico AT pesqueirafontanpaulamaria telangiectasiahemorragicahereditariatratamientofarmacologico AT diazperomingojoseantonio telangiectasiahemorragicahereditariatratamientofarmacologico
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Telangiectasia hemorrágica hereditaria: Tratamiento farmacológico

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