Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios
Background: Patients with type 2 diabetes have a high incidence of coronary artery disease, which is even higher among those with renal failure. A serum level of cystatin C are used to assess renal function and is a potential cardiovascular risk factor. Adiponectin is an anti-atherogenic factor. Aim...
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Sociedad Médica de Santiago
2009
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oai:scielo:S0034-988720090006000012009-09-04Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronariosWolff F,CarlosDurruty A,PilarEspinoza R,JaimeRipamonti Z,SoledadDíaz C,Jaime Adiponectin Coronary artery disease Diabetes mellitus type 2 Background: Patients with type 2 diabetes have a high incidence of coronary artery disease, which is even higher among those with renal failure. A serum level of cystatin C are used to assess renal function and is a potential cardiovascular risk factor. Adiponectin is an anti-atherogenic factor. Aim: To measure cystatin C and adiponectin in type 2 diabetic patients with and without coronary artery disease. Material and methods: Nine diabetic patients with coronary artery disease aged 76± 10 years, 20 diabetics without coronary artery disease aged 61 ±5 years and 20 non diabetic subjects aged 57±10 years, were studied. Results: Serum levels of cystatin C (mg/L) were 1.5 (range 0.89-219), 0.81 (range 0.71-1.08) and 0.68 mg/L (range 055-0.75) in diabetics with and without coronary artery disease and controls, respectively (p <0.0001). No differences in adiponectin between groups and no association between cystatin C and adiponectin, were observed. No association between both parameters and body mass index orglycosilated hemoglobin Ale was observed. Cystatin C had a positive correlation with serum creatinine (r =0.57p <0.001). Conclusions: Diabetics with coronary artery disease have higher levels of cystatin C, that are closely correlated with serum creatinine levels.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.6 20092009-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000600001es10.4067/S0034-98872009000600001 |
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Scielo Chile |
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Scielo Chile |
language |
Spanish / Castilian |
topic |
Adiponectin Coronary artery disease Diabetes mellitus type 2 |
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Adiponectin Coronary artery disease Diabetes mellitus type 2 Wolff F,Carlos Durruty A,Pilar Espinoza R,Jaime Ripamonti Z,Soledad Díaz C,Jaime Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios |
description |
Background: Patients with type 2 diabetes have a high incidence of coronary artery disease, which is even higher among those with renal failure. A serum level of cystatin C are used to assess renal function and is a potential cardiovascular risk factor. Adiponectin is an anti-atherogenic factor. Aim: To measure cystatin C and adiponectin in type 2 diabetic patients with and without coronary artery disease. Material and methods: Nine diabetic patients with coronary artery disease aged 76± 10 years, 20 diabetics without coronary artery disease aged 61 ±5 years and 20 non diabetic subjects aged 57±10 years, were studied. Results: Serum levels of cystatin C (mg/L) were 1.5 (range 0.89-219), 0.81 (range 0.71-1.08) and 0.68 mg/L (range 055-0.75) in diabetics with and without coronary artery disease and controls, respectively (p <0.0001). No differences in adiponectin between groups and no association between cystatin C and adiponectin, were observed. No association between both parameters and body mass index orglycosilated hemoglobin Ale was observed. Cystatin C had a positive correlation with serum creatinine (r =0.57p <0.001). Conclusions: Diabetics with coronary artery disease have higher levels of cystatin C, that are closely correlated with serum creatinine levels. |
author |
Wolff F,Carlos Durruty A,Pilar Espinoza R,Jaime Ripamonti Z,Soledad Díaz C,Jaime |
author_facet |
Wolff F,Carlos Durruty A,Pilar Espinoza R,Jaime Ripamonti Z,Soledad Díaz C,Jaime |
author_sort |
Wolff F,Carlos |
title |
Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios |
title_short |
Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios |
title_full |
Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios |
title_fullStr |
Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios |
title_full_unstemmed |
Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios |
title_sort |
cistatina c y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios |
publisher |
Sociedad Médica de Santiago |
publishDate |
2009 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000600001 |
work_keys_str_mv |
AT wolfffcarlos cistatinacyadiponectinaenpacientesdiabeticostipo2coronariosynocoronarios AT durrutyapilar cistatinacyadiponectinaenpacientesdiabeticostipo2coronariosynocoronarios AT espinozarjaime cistatinacyadiponectinaenpacientesdiabeticostipo2coronariosynocoronarios AT ripamontizsoledad cistatinacyadiponectinaenpacientesdiabeticostipo2coronariosynocoronarios AT diazcjaime cistatinacyadiponectinaenpacientesdiabeticostipo2coronariosynocoronarios |
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