Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios

Background: Patients with type 2 diabetes have a high incidence of coronary artery disease, which is even higher among those with renal failure. A serum level of cystatin C are used to assess renal function and is a potential cardiovascular risk factor. Adiponectin is an anti-atherogenic factor. Aim...

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Autores principales: Wolff F,Carlos, Durruty A,Pilar, Espinoza R,Jaime, Ripamonti Z,Soledad, Díaz C,Jaime
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2009
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000600001
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spelling oai:scielo:S0034-988720090006000012009-09-04Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronariosWolff F,CarlosDurruty A,PilarEspinoza R,JaimeRipamonti Z,SoledadDíaz C,Jaime Adiponectin Coronary artery disease Diabetes mellitus type 2 Background: Patients with type 2 diabetes have a high incidence of coronary artery disease, which is even higher among those with renal failure. A serum level of cystatin C are used to assess renal function and is a potential cardiovascular risk factor. Adiponectin is an anti-atherogenic factor. Aim: To measure cystatin C and adiponectin in type 2 diabetic patients with and without coronary artery disease. Material and methods: Nine diabetic patients with coronary artery disease aged 76± 10 years, 20 diabetics without coronary artery disease aged 61 ±5 years and 20 non diabetic subjects aged 57±10 years, were studied. Results: Serum levels of cystatin C (mg/L) were 1.5 (range 0.89-219), 0.81 (range 0.71-1.08) and 0.68 mg/L (range 055-0.75) in diabetics with and without coronary artery disease and controls, respectively (p <0.0001). No differences in adiponectin between groups and no association between cystatin C and adiponectin, were observed. No association between both parameters and body mass index orglycosilated hemoglobin Ale was observed. Cystatin C had a positive correlation with serum creatinine (r =0.57p <0.001). Conclusions: Diabetics with coronary artery disease have higher levels of cystatin C, that are closely correlated with serum creatinine levels.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.6 20092009-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000600001es10.4067/S0034-98872009000600001
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Adiponectin
Coronary artery disease
Diabetes mellitus
type 2
spellingShingle Adiponectin
Coronary artery disease
Diabetes mellitus
type 2
Wolff F,Carlos
Durruty A,Pilar
Espinoza R,Jaime
Ripamonti Z,Soledad
Díaz C,Jaime
Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios
description Background: Patients with type 2 diabetes have a high incidence of coronary artery disease, which is even higher among those with renal failure. A serum level of cystatin C are used to assess renal function and is a potential cardiovascular risk factor. Adiponectin is an anti-atherogenic factor. Aim: To measure cystatin C and adiponectin in type 2 diabetic patients with and without coronary artery disease. Material and methods: Nine diabetic patients with coronary artery disease aged 76± 10 years, 20 diabetics without coronary artery disease aged 61 ±5 years and 20 non diabetic subjects aged 57±10 years, were studied. Results: Serum levels of cystatin C (mg/L) were 1.5 (range 0.89-219), 0.81 (range 0.71-1.08) and 0.68 mg/L (range 055-0.75) in diabetics with and without coronary artery disease and controls, respectively (p <0.0001). No differences in adiponectin between groups and no association between cystatin C and adiponectin, were observed. No association between both parameters and body mass index orglycosilated hemoglobin Ale was observed. Cystatin C had a positive correlation with serum creatinine (r =0.57p <0.001). Conclusions: Diabetics with coronary artery disease have higher levels of cystatin C, that are closely correlated with serum creatinine levels.
author Wolff F,Carlos
Durruty A,Pilar
Espinoza R,Jaime
Ripamonti Z,Soledad
Díaz C,Jaime
author_facet Wolff F,Carlos
Durruty A,Pilar
Espinoza R,Jaime
Ripamonti Z,Soledad
Díaz C,Jaime
author_sort Wolff F,Carlos
title Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios
title_short Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios
title_full Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios
title_fullStr Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios
title_full_unstemmed Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios
title_sort cistatina c y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios
publisher Sociedad Médica de Santiago
publishDate 2009
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000600001
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