Hipotermia intravascular inducida en el manejo de la hipertensión intracraneana en insuficiencia hepática aguda: Caso clínico

Acute liver failure has a mortality rate in excess of 80%. Most deaths are attributed to brain edema with intracranial hypertension and herniation of structures, where ammonium plays a major role in its generation. We report an 18 year-old female with a fulminant hepatic failure caused by virus A in...

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Autores principales: Castillo F,Luis, Pérez R,Cristian, Ruiz B,Carolina, Bugedo T,Guillermo, Hernández P,Glenn, Martínez C,Jorge, Jarufe C,Nicolás, Pérez A,Rosa, Mellado T,Patricio, Domínguez,Pilar
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2009
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000600010
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spelling oai:scielo:S0034-988720090006000102009-09-04Hipotermia intravascular inducida en el manejo de la hipertensión intracraneana en insuficiencia hepática aguda: Caso clínicoCastillo F,LuisPérez R,CristianRuiz B,CarolinaBugedo T,GuillermoHernández P,GlennMartínez C,JorgeJarufe C,NicolásPérez A,RosaMellado T,PatricioDomínguez,Pilar Brain edema Hypothermia Liver failure, acute Acute liver failure has a mortality rate in excess of 80%. Most deaths are attributed to brain edema with intracranial hypertension and herniation of structures, where ammonium plays a major role in its generation. We report an 18 year-old female with a fulminant hepatic failure caused by virus A infection. The patient developed a profound sopor and required mechanical ventilation. A CT scan showed the presence of brain edema and intracranial hypertension. A Raudemic® catheter was inserted to measure intracranial pressure and brain temperature. Intracranial hypertension became refractory and intravascular hypothermia was started, reducing brain temperature to 33°C. Seventy two hours later, a liver transplantation was performed. After testing graft perfusion, rewarming was started, completing 122 hours of hypothermia at 33°C. The patient was discharged in good conditions after 69 days of hospitalization.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.6 20092009-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000600010es10.4067/S0034-98872009000600010
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Brain edema
Hypothermia
Liver failure, acute
spellingShingle Brain edema
Hypothermia
Liver failure, acute
Castillo F,Luis
Pérez R,Cristian
Ruiz B,Carolina
Bugedo T,Guillermo
Hernández P,Glenn
Martínez C,Jorge
Jarufe C,Nicolás
Pérez A,Rosa
Mellado T,Patricio
Domínguez,Pilar
Hipotermia intravascular inducida en el manejo de la hipertensión intracraneana en insuficiencia hepática aguda: Caso clínico
description Acute liver failure has a mortality rate in excess of 80%. Most deaths are attributed to brain edema with intracranial hypertension and herniation of structures, where ammonium plays a major role in its generation. We report an 18 year-old female with a fulminant hepatic failure caused by virus A infection. The patient developed a profound sopor and required mechanical ventilation. A CT scan showed the presence of brain edema and intracranial hypertension. A Raudemic® catheter was inserted to measure intracranial pressure and brain temperature. Intracranial hypertension became refractory and intravascular hypothermia was started, reducing brain temperature to 33°C. Seventy two hours later, a liver transplantation was performed. After testing graft perfusion, rewarming was started, completing 122 hours of hypothermia at 33°C. The patient was discharged in good conditions after 69 days of hospitalization.
author Castillo F,Luis
Pérez R,Cristian
Ruiz B,Carolina
Bugedo T,Guillermo
Hernández P,Glenn
Martínez C,Jorge
Jarufe C,Nicolás
Pérez A,Rosa
Mellado T,Patricio
Domínguez,Pilar
author_facet Castillo F,Luis
Pérez R,Cristian
Ruiz B,Carolina
Bugedo T,Guillermo
Hernández P,Glenn
Martínez C,Jorge
Jarufe C,Nicolás
Pérez A,Rosa
Mellado T,Patricio
Domínguez,Pilar
author_sort Castillo F,Luis
title Hipotermia intravascular inducida en el manejo de la hipertensión intracraneana en insuficiencia hepática aguda: Caso clínico
title_short Hipotermia intravascular inducida en el manejo de la hipertensión intracraneana en insuficiencia hepática aguda: Caso clínico
title_full Hipotermia intravascular inducida en el manejo de la hipertensión intracraneana en insuficiencia hepática aguda: Caso clínico
title_fullStr Hipotermia intravascular inducida en el manejo de la hipertensión intracraneana en insuficiencia hepática aguda: Caso clínico
title_full_unstemmed Hipotermia intravascular inducida en el manejo de la hipertensión intracraneana en insuficiencia hepática aguda: Caso clínico
title_sort hipotermia intravascular inducida en el manejo de la hipertensión intracraneana en insuficiencia hepática aguda: caso clínico
publisher Sociedad Médica de Santiago
publishDate 2009
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000600010
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