Síndrome metabólico en un grupo de pacientes diabéticos tipo 1. ¿Una nueva variedad de diabetes?

Background: Metabolic Syndrome (MS) is related to insulin resistance and to type 2 diabetes mellitus. However, patients with type 1 diabetes mellitus (T1DM) may also develop this condition. Aim: To determine the prevalence of MS in patients with T1DM. Material and methods: Cross sectional study of 5...

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Autores principales: Báez,María Soledad, Novik A,Victoria, Alegría G,Felipe, Cardemil M,Felipe, Riveros P,Rodrigo, Bofill Ch,Luis
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2009
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000700004
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spelling oai:scielo:S0034-988720090007000042010-04-29Síndrome metabólico en un grupo de pacientes diabéticos tipo 1. ¿Una nueva variedad de diabetes?Báez,María SoledadNovik A,VictoriaAlegría G,FelipeCardemil M,FelipeRiveros P,RodrigoBofill Ch,Luis Diabetes mellitus, type 1 Insulin resistance Metabolic syndrome X Background: Metabolic Syndrome (MS) is related to insulin resistance and to type 2 diabetes mellitus. However, patients with type 1 diabetes mellitus (T1DM) may also develop this condition. Aim: To determine the prevalence of MS in patients with T1DM. Material and methods: Cross sectional study of 52 patients with T1DM aged 18 to 72 years (27 females) with 5 years or more since their diagnosis of T1DM. MS presence was defined according to the Adult Treatment Panel III criteria. Acanthosis nigricans (AN), waist circumference (WC), daily dose of insulin, glycosylated hemoglobin (HbAlc) and micro albuminuria were evaluated. Results: The prevalence of MS was 25% (13/52). A higher daily dose of insulin was required in patients with MS (p =0.018), with AN (p =0.022) and with obesity (p =0.002). A direct association between WC and the dose of insulin was observed (r =0.51; p <0.0001). No association was observed between MS, time of evolution of T1DM, HbAlc or micro albuminuria. Conclusions: In this group of patients with T1DM there was a high prevalence of MS.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.7 20092009-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000700004es10.4067/S0034-98872009000700004
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Diabetes mellitus, type 1
Insulin resistance
Metabolic syndrome X
spellingShingle Diabetes mellitus, type 1
Insulin resistance
Metabolic syndrome X
Báez,María Soledad
Novik A,Victoria
Alegría G,Felipe
Cardemil M,Felipe
Riveros P,Rodrigo
Bofill Ch,Luis
Síndrome metabólico en un grupo de pacientes diabéticos tipo 1. ¿Una nueva variedad de diabetes?
description Background: Metabolic Syndrome (MS) is related to insulin resistance and to type 2 diabetes mellitus. However, patients with type 1 diabetes mellitus (T1DM) may also develop this condition. Aim: To determine the prevalence of MS in patients with T1DM. Material and methods: Cross sectional study of 52 patients with T1DM aged 18 to 72 years (27 females) with 5 years or more since their diagnosis of T1DM. MS presence was defined according to the Adult Treatment Panel III criteria. Acanthosis nigricans (AN), waist circumference (WC), daily dose of insulin, glycosylated hemoglobin (HbAlc) and micro albuminuria were evaluated. Results: The prevalence of MS was 25% (13/52). A higher daily dose of insulin was required in patients with MS (p =0.018), with AN (p =0.022) and with obesity (p =0.002). A direct association between WC and the dose of insulin was observed (r =0.51; p <0.0001). No association was observed between MS, time of evolution of T1DM, HbAlc or micro albuminuria. Conclusions: In this group of patients with T1DM there was a high prevalence of MS.
author Báez,María Soledad
Novik A,Victoria
Alegría G,Felipe
Cardemil M,Felipe
Riveros P,Rodrigo
Bofill Ch,Luis
author_facet Báez,María Soledad
Novik A,Victoria
Alegría G,Felipe
Cardemil M,Felipe
Riveros P,Rodrigo
Bofill Ch,Luis
author_sort Báez,María Soledad
title Síndrome metabólico en un grupo de pacientes diabéticos tipo 1. ¿Una nueva variedad de diabetes?
title_short Síndrome metabólico en un grupo de pacientes diabéticos tipo 1. ¿Una nueva variedad de diabetes?
title_full Síndrome metabólico en un grupo de pacientes diabéticos tipo 1. ¿Una nueva variedad de diabetes?
title_fullStr Síndrome metabólico en un grupo de pacientes diabéticos tipo 1. ¿Una nueva variedad de diabetes?
title_full_unstemmed Síndrome metabólico en un grupo de pacientes diabéticos tipo 1. ¿Una nueva variedad de diabetes?
title_sort síndrome metabólico en un grupo de pacientes diabéticos tipo 1. ¿una nueva variedad de diabetes?
publisher Sociedad Médica de Santiago
publishDate 2009
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000700004
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