Fenómeno de acomodación inmunológica: Trasplante hepático ABO incompatible. Caso clínico

We report a 33 year-old female with a diagnosis of halothane-induce fulminant hepatic failure who was subjected to a liver transplant with an ABO-incompatible graft. The patient received a therapeutic protocol that included total plasma exchange, splenectomy and quadruple immunosuppression. After 5...

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Autores principales: Castro,Lorena, Yarur,Andrés, Segovia,Roberto, Ponce,Rodrigo, Uribe,Mario, Ferrario,Mario, Buckel,Erwin, Iturriaga,Hernán
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2009
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000800010
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spelling oai:scielo:S0034-988720090008000102009-11-04Fenómeno de acomodación inmunológica: Trasplante hepático ABO incompatible. Caso clínicoCastro,LorenaYarur,AndrésSegovia,RobertoPonce,RodrigoUribe,MarioFerrario,MarioBuckel,ErwinIturriaga,Hernán ABO Blood-group system Allergy and Immunology Liver transplantation We report a 33 year-old female with a diagnosis of halothane-induce fulminant hepatic failure who was subjected to a liver transplant with an ABO-incompatible graft. The patient received a therapeutic protocol that included total plasma exchange, splenectomy and quadruple immunosuppression. After 5 years, the patient remains asymptomatic and with normal liver enzymes, while she has been treated with low dose of immunosuppressive drugs. This case demonstrates an example of how the immunological process of accomodation opens the possibility of using ABO-incompatible organs as a definitive grafts.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.8 20092009-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000800010es10.4067/S0034-98872009000800010
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic ABO Blood-group system
Allergy and Immunology
Liver transplantation
spellingShingle ABO Blood-group system
Allergy and Immunology
Liver transplantation
Castro,Lorena
Yarur,Andrés
Segovia,Roberto
Ponce,Rodrigo
Uribe,Mario
Ferrario,Mario
Buckel,Erwin
Iturriaga,Hernán
Fenómeno de acomodación inmunológica: Trasplante hepático ABO incompatible. Caso clínico
description We report a 33 year-old female with a diagnosis of halothane-induce fulminant hepatic failure who was subjected to a liver transplant with an ABO-incompatible graft. The patient received a therapeutic protocol that included total plasma exchange, splenectomy and quadruple immunosuppression. After 5 years, the patient remains asymptomatic and with normal liver enzymes, while she has been treated with low dose of immunosuppressive drugs. This case demonstrates an example of how the immunological process of accomodation opens the possibility of using ABO-incompatible organs as a definitive grafts.
author Castro,Lorena
Yarur,Andrés
Segovia,Roberto
Ponce,Rodrigo
Uribe,Mario
Ferrario,Mario
Buckel,Erwin
Iturriaga,Hernán
author_facet Castro,Lorena
Yarur,Andrés
Segovia,Roberto
Ponce,Rodrigo
Uribe,Mario
Ferrario,Mario
Buckel,Erwin
Iturriaga,Hernán
author_sort Castro,Lorena
title Fenómeno de acomodación inmunológica: Trasplante hepático ABO incompatible. Caso clínico
title_short Fenómeno de acomodación inmunológica: Trasplante hepático ABO incompatible. Caso clínico
title_full Fenómeno de acomodación inmunológica: Trasplante hepático ABO incompatible. Caso clínico
title_fullStr Fenómeno de acomodación inmunológica: Trasplante hepático ABO incompatible. Caso clínico
title_full_unstemmed Fenómeno de acomodación inmunológica: Trasplante hepático ABO incompatible. Caso clínico
title_sort fenómeno de acomodación inmunológica: trasplante hepático abo incompatible. caso clínico
publisher Sociedad Médica de Santiago
publishDate 2009
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000800010
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