Validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpables

Background: During the surgical treatment of breast neoplasms (benign or malignant), frozen section biopsy is frequently requested to assess the kind of lesion and determine the surgical margins. Aim: To assess the diagnostic yield of frozen section breast biopsy. Material and methods: AH the pathol...

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Autores principales:	Bellolio J,Enrique, Guzmán G,Pablo, Orellana C,Juan, Roa S,Juan Carlos, Villaseca H,Miguel, Araya O,Juan Carlos, Tapia E,Oscar, ineda N,Viviana
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2009
Materias:	Biopsy Breast neoplasms Frozen sections
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000900005
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spelling	oai:scielo:S0034-988720090009000052009-11-09Validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpablesBellolio J,EnriqueGuzmán G,PabloOrellana C,JuanRoa S,Juan CarlosVillaseca H,MiguelAraya O,Juan CarlosTapia E,Oscarineda N,Viviana Biopsy Breast neoplasms Frozen sections Background: During the surgical treatment of breast neoplasms (benign or malignant), frozen section biopsy is frequently requested to assess the kind of lesion and determine the surgical margins. Aim: To assess the diagnostic yield of frozen section breast biopsy. Material and methods: AH the pathological reports of frozen section biopsies and definitive biopsies of 337 women aged 26 to 88 years, operated for suspected breast neoplasms between 2002 and 2006, were reviewed. The sensitivity, specificity and predictive value of frozen section biopsy, were calculated using the definitive biopsy as the gold standard. Results: The definitive biopsy confirmed the presence of cancer in 290 women (86%). There were two false negative (0.59%) and no false positive frozen section biopsies for cancer detection. The sensibility for cancer detection was 99.3% and the specificity 100%. The positive predictive value was 100% and the negative predictive value 96.1%. The diagnosis of phyllodes tumor was missed by frozen section biopsy in three cases. The margins were informed in the 258 frozen section biopsies (79%) and in 59 cases (18%), these were positive for cancer. Conclusions: Frozen section biopsy is useful and reliable for cancer detection and margin status assessment in breast cancer surgery (RevMéd Chile 2009; 137: 1173-8).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.9 20092009-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000900005es10.4067/S0034-98872009000900005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Biopsy Breast neoplasms Frozen sections
spellingShingle	Biopsy Breast neoplasms Frozen sections Bellolio J,Enrique Guzmán G,Pablo Orellana C,Juan Roa S,Juan Carlos Villaseca H,Miguel Araya O,Juan Carlos Tapia E,Oscar ineda N,Viviana Validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpables
description	Background: During the surgical treatment of breast neoplasms (benign or malignant), frozen section biopsy is frequently requested to assess the kind of lesion and determine the surgical margins. Aim: To assess the diagnostic yield of frozen section breast biopsy. Material and methods: AH the pathological reports of frozen section biopsies and definitive biopsies of 337 women aged 26 to 88 years, operated for suspected breast neoplasms between 2002 and 2006, were reviewed. The sensitivity, specificity and predictive value of frozen section biopsy, were calculated using the definitive biopsy as the gold standard. Results: The definitive biopsy confirmed the presence of cancer in 290 women (86%). There were two false negative (0.59%) and no false positive frozen section biopsies for cancer detection. The sensibility for cancer detection was 99.3% and the specificity 100%. The positive predictive value was 100% and the negative predictive value 96.1%. The diagnosis of phyllodes tumor was missed by frozen section biopsy in three cases. The margins were informed in the 258 frozen section biopsies (79%) and in 59 cases (18%), these were positive for cancer. Conclusions: Frozen section biopsy is useful and reliable for cancer detection and margin status assessment in breast cancer surgery (RevMéd Chile 2009; 137: 1173-8).
author	Bellolio J,Enrique Guzmán G,Pablo Orellana C,Juan Roa S,Juan Carlos Villaseca H,Miguel Araya O,Juan Carlos Tapia E,Oscar ineda N,Viviana
author_facet	Bellolio J,Enrique Guzmán G,Pablo Orellana C,Juan Roa S,Juan Carlos Villaseca H,Miguel Araya O,Juan Carlos Tapia E,Oscar ineda N,Viviana
author_sort	Bellolio J,Enrique
title	Validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpables
title_short	Validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpables
title_full	Validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpables
title_fullStr	Validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpables
title_full_unstemmed	Validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpables
title_sort	validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpables
publisher	Sociedad Médica de Santiago
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000900005
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Validez diagnóstica de la biopsia intraoperatoria en cirugía de lesiones mamarias palpables

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