La disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardio

Background: Cardiac dyssynchrony is common in advanced heart failure (HF), but the changes in cardiac synchrony after myocardial infarction (MI) have not been adequately descríbed. Aim: To study the relationship between cardiac synchrony and left ventricular remodeling after acute myocardial infarct...

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Autores principales:	McNab,Paul, Castro,Pablo, Gabrielli,Luigi, Verdejo,Hugo, Quintana,Juan Carlos, Rodríguez,José A, Corbalán,Ramón
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2009
Materias:	Cardiac dyssynchrony Myocardial infarction Ventricular remodeling
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009001100007
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spelling	oai:scielo:S0034-988720090011000072010-01-13La disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardioMcNab,PaulCastro,PabloGabrielli,LuigiVerdejo,HugoQuintana,Juan CarlosRodríguez,José ACorbalán,Ramón Cardiac dyssynchrony Myocardial infarction Ventricular remodeling Background: Cardiac dyssynchrony is common in advanced heart failure (HF), but the changes in cardiac synchrony after myocardial infarction (MI) have not been adequately descríbed. Aim: To study the relationship between cardiac synchrony and left ventricular remodeling after acute myocardial infarction. Material and methods: Forty nine patients aged 59±10 years (77% men) with a first episode of a ST segment elevation MI, were studied. Scintigraphic left ventricular function and synchrony analyses were performed at baseline and after a six months follow-up. Determinations were compared with 33 healthy subjects. Results: At baseline, patients with MIhad a decreased left ventricular ejection fraction (LVEF) and significant dyssynchrony, when compared with controls. LVEF was 36.4%±10%, left ventricular end-diastolic volume (LVEDV) 127±38 mL, interventricular delay (IEV) 29±35 miliseconds (ms), and intraventricular delay (IAV), 234±89 ms. After 6 months, LVEF significantly improved (38%±10%, p =0.042) without significant changes in LVEDV (129±32 mL, p =0.97), IEV (24±17, p =0.96) or IAV (231±97, p =0.34). At baseline there were significant correlations between IAV and LVEF, and between IAV and LVEDV (r =0.48, p =0.001 and r =0.41, p =0.004, respectively). These correlations remained significant after 6 months. There was a positive correlation between IAV and LVEDV changes at six months (r =0.403, p =0.04). Conclusions: The development of cardiac dyssynchrony correlates with adverse left ventricular remodeling after MI .info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.137 n.11 20092009-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009001100007es10.4067/S0034-98872009001100007
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Cardiac dyssynchrony Myocardial infarction Ventricular remodeling
spellingShingle	Cardiac dyssynchrony Myocardial infarction Ventricular remodeling McNab,Paul Castro,Pablo Gabrielli,Luigi Verdejo,Hugo Quintana,Juan Carlos Rodríguez,José A Corbalán,Ramón La disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardio
description	Background: Cardiac dyssynchrony is common in advanced heart failure (HF), but the changes in cardiac synchrony after myocardial infarction (MI) have not been adequately descríbed. Aim: To study the relationship between cardiac synchrony and left ventricular remodeling after acute myocardial infarction. Material and methods: Forty nine patients aged 59±10 years (77% men) with a first episode of a ST segment elevation MI, were studied. Scintigraphic left ventricular function and synchrony analyses were performed at baseline and after a six months follow-up. Determinations were compared with 33 healthy subjects. Results: At baseline, patients with MIhad a decreased left ventricular ejection fraction (LVEF) and significant dyssynchrony, when compared with controls. LVEF was 36.4%±10%, left ventricular end-diastolic volume (LVEDV) 127±38 mL, interventricular delay (IEV) 29±35 miliseconds (ms), and intraventricular delay (IAV), 234±89 ms. After 6 months, LVEF significantly improved (38%±10%, p =0.042) without significant changes in LVEDV (129±32 mL, p =0.97), IEV (24±17, p =0.96) or IAV (231±97, p =0.34). At baseline there were significant correlations between IAV and LVEF, and between IAV and LVEDV (r =0.48, p =0.001 and r =0.41, p =0.004, respectively). These correlations remained significant after 6 months. There was a positive correlation between IAV and LVEDV changes at six months (r =0.403, p =0.04). Conclusions: The development of cardiac dyssynchrony correlates with adverse left ventricular remodeling after MI .
author	McNab,Paul Castro,Pablo Gabrielli,Luigi Verdejo,Hugo Quintana,Juan Carlos Rodríguez,José A Corbalán,Ramón
author_facet	McNab,Paul Castro,Pablo Gabrielli,Luigi Verdejo,Hugo Quintana,Juan Carlos Rodríguez,José A Corbalán,Ramón
author_sort	McNab,Paul
title	La disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardio
title_short	La disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardio
title_full	La disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardio
title_fullStr	La disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardio
title_full_unstemmed	La disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardio
title_sort	la disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardio
publisher	Sociedad Médica de Santiago
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009001100007
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La disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardio

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