Manipulación del transporte y consumo de oxígeno en la sepsis

Maintaining an adequate tissue oxygen delivery (DO) and consumption (VO) is crucial in the treatment of septic patients. A fall in V02 is associated with a higher mortality. The early recognition of shock or tissue hypo perfusion impacts on patient prognosis. In occasions, hypovolemia or important r...

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Autores principales:	REGUEIRA,TOMAS, ANDRESEN,MAX
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Anoxia Sepsis Shock
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000200014
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spelling	oai:scielo:S0034-988720100002000142010-03-30Manipulación del transporte y consumo de oxígeno en la sepsisREGUEIRA,TOMASANDRESEN,MAX Anoxia Sepsis Shock Maintaining an adequate tissue oxygen delivery (DO) and consumption (VO) is crucial in the treatment of septic patients. A fall in V02 is associated with a higher mortality. The early recognition of shock or tissue hypo perfusion impacts on patient prognosis. In occasions, hypovolemia or important regional oxygen debts are not recognized, since macro homodynamic variables have been compensated. In this situation, the use of metabolic hypo perfusion markers such as lactate, central venous oxygen saturation and gastric goniometry, can be helpful. However, interpretation of these markers should be cautious and always considering the overall clinical status of the patient. In the initial stages of sepsis, the dependency ofV02 on DO 2predominates as histopathological mechanism of multiple organic failure. In late stages, other factors predominate as determinants of multiple organic failure and mortality, such as hyper or hypo immune response, microcirculatory alterations and cytopathic hypoxia.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.2 20102010-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000200014es10.4067/S0034-98872010000200014
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Anoxia Sepsis Shock
spellingShingle	Anoxia Sepsis Shock REGUEIRA,TOMAS ANDRESEN,MAX Manipulación del transporte y consumo de oxígeno en la sepsis
description	Maintaining an adequate tissue oxygen delivery (DO) and consumption (VO) is crucial in the treatment of septic patients. A fall in V02 is associated with a higher mortality. The early recognition of shock or tissue hypo perfusion impacts on patient prognosis. In occasions, hypovolemia or important regional oxygen debts are not recognized, since macro homodynamic variables have been compensated. In this situation, the use of metabolic hypo perfusion markers such as lactate, central venous oxygen saturation and gastric goniometry, can be helpful. However, interpretation of these markers should be cautious and always considering the overall clinical status of the patient. In the initial stages of sepsis, the dependency ofV02 on DO 2predominates as histopathological mechanism of multiple organic failure. In late stages, other factors predominate as determinants of multiple organic failure and mortality, such as hyper or hypo immune response, microcirculatory alterations and cytopathic hypoxia.
author	REGUEIRA,TOMAS ANDRESEN,MAX
author_facet	REGUEIRA,TOMAS ANDRESEN,MAX
author_sort	REGUEIRA,TOMAS
title	Manipulación del transporte y consumo de oxígeno en la sepsis
title_short	Manipulación del transporte y consumo de oxígeno en la sepsis
title_full	Manipulación del transporte y consumo de oxígeno en la sepsis
title_fullStr	Manipulación del transporte y consumo de oxígeno en la sepsis
title_full_unstemmed	Manipulación del transporte y consumo de oxígeno en la sepsis
title_sort	manipulación del transporte y consumo de oxígeno en la sepsis
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000200014
work_keys_str_mv	AT regueiratomas manipulaciondeltransporteyconsumodeoxigenoenlasepsis AT andresenmax manipulaciondeltransporteyconsumodeoxigenoenlasepsis
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Manipulación del transporte y consumo de oxígeno en la sepsis

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