Recuento leucocitario y riesgo cardiovascular tras un síndrome coronario agudo

Background: Leukocytosis occurs as a response to a variety of infammatory processes. Aim: To determine if white blood cell count (WBCC) at admission among patients who suffer an acute coronary syndrome (ACS) has an independent prog-nostic value for the occurrence of new cardiovascular adverse events...

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Autores principales:	CABRERIZO G,JOSÉ LUIS, ZALBA E,BEGOÑA, PÉREZ C,JUAN I, RUIZ R,FRANCISCO
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Acute coronary syndrome Leucocyte count Prognosis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300003
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spelling	oai:scielo:S0034-988720100003000032010-05-19Recuento leucocitario y riesgo cardiovascular tras un síndrome coronario agudoCABRERIZO G,JOSÉ LUISZALBA E,BEGOÑAPÉREZ C,JUAN IRUIZ R,FRANCISCO Acute coronary syndrome Leucocyte count Prognosis Background: Leukocytosis occurs as a response to a variety of infammatory processes. Aim: To determine if white blood cell count (WBCC) at admission among patients who suffer an acute coronary syndrome (ACS) has an independent prog-nostic value for the occurrence of new cardiovascular adverse events (CAE). Patients and Methods: Prospective study of 558 patients aged 68 ± 13 years (122 women) admitted to the hospital for an acute coronary syndrome. WBCC was measured at admission. A logistic regression model was used to assess the association of WBCC with the occurrence of CAE during the next six months after admission (post infarction angina, re-infarction, cardiac failure and mortality). Results: An univariate analysis showed that patients with a WBCC > 15.000 cell/mm³ had a signifcantly higher mortality and occurrence of CAE. The multivariate analysis showed that subjects with WBCC < 10.000 cell/mm³ experienced fewer CAE than subjects with a WBCC > 15.000 cell/mm³, with an odds ratio of 0.46 (95% confdence intervals = 0.21-0.97, p = 0,042). Conclusions: An elevated WBCC at admission among patients with an ACS is associated with a higher incidence of CAE in the ensuing six months.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.3 20102010-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300003es10.4067/S0034-98872010000300003
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Acute coronary syndrome Leucocyte count Prognosis
spellingShingle	Acute coronary syndrome Leucocyte count Prognosis CABRERIZO G,JOSÉ LUIS ZALBA E,BEGOÑA PÉREZ C,JUAN I RUIZ R,FRANCISCO Recuento leucocitario y riesgo cardiovascular tras un síndrome coronario agudo
description	Background: Leukocytosis occurs as a response to a variety of infammatory processes. Aim: To determine if white blood cell count (WBCC) at admission among patients who suffer an acute coronary syndrome (ACS) has an independent prog-nostic value for the occurrence of new cardiovascular adverse events (CAE). Patients and Methods: Prospective study of 558 patients aged 68 ± 13 years (122 women) admitted to the hospital for an acute coronary syndrome. WBCC was measured at admission. A logistic regression model was used to assess the association of WBCC with the occurrence of CAE during the next six months after admission (post infarction angina, re-infarction, cardiac failure and mortality). Results: An univariate analysis showed that patients with a WBCC > 15.000 cell/mm³ had a signifcantly higher mortality and occurrence of CAE. The multivariate analysis showed that subjects with WBCC < 10.000 cell/mm³ experienced fewer CAE than subjects with a WBCC > 15.000 cell/mm³, with an odds ratio of 0.46 (95% confdence intervals = 0.21-0.97, p = 0,042). Conclusions: An elevated WBCC at admission among patients with an ACS is associated with a higher incidence of CAE in the ensuing six months.
author	CABRERIZO G,JOSÉ LUIS ZALBA E,BEGOÑA PÉREZ C,JUAN I RUIZ R,FRANCISCO
author_facet	CABRERIZO G,JOSÉ LUIS ZALBA E,BEGOÑA PÉREZ C,JUAN I RUIZ R,FRANCISCO
author_sort	CABRERIZO G,JOSÉ LUIS
title	Recuento leucocitario y riesgo cardiovascular tras un síndrome coronario agudo
title_short	Recuento leucocitario y riesgo cardiovascular tras un síndrome coronario agudo
title_full	Recuento leucocitario y riesgo cardiovascular tras un síndrome coronario agudo
title_fullStr	Recuento leucocitario y riesgo cardiovascular tras un síndrome coronario agudo
title_full_unstemmed	Recuento leucocitario y riesgo cardiovascular tras un síndrome coronario agudo
title_sort	recuento leucocitario y riesgo cardiovascular tras un síndrome coronario agudo
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300003
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Recuento leucocitario y riesgo cardiovascular tras un síndrome coronario agudo

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