Pancreatitis autoinmune: Experiencia clínica y revisión de la literatura

Background: Autoimmune pancreatitis is a special form of chronic pancreatitis, more common in men and usually presenting as obstructive jaundice or abdominal pain. It may be associated with other immunological disorders and sometimes it is possible to find positive serological markers. Typical image...

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Autores principales: MUÑOZ C,SERGIO, MANCILLA A,CARLA, MOYANO S,LEONOR, CASTILLO T,CECILIA, ROSSI F,RICARDO, BRAHM B,JAVIER, BERGER F,ZOLTÁN
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2010
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300006
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spelling oai:scielo:S0034-988720100003000062010-05-19Pancreatitis autoinmune: Experiencia clínica y revisión de la literaturaMUÑOZ C,SERGIOMANCILLA A,CARLAMOYANO S,LEONORCASTILLO T,CECILIAROSSI F,RICARDOBRAHM B,JAVIERBERGER F,ZOLTÁN Autoimmunity Pancreatitis, chronic Prednisone Background: Autoimmune pancreatitis is a special form of chronic pancreatitis, more common in men and usually presenting as obstructive jaundice or abdominal pain. It may be associated with other immunological disorders and sometimes it is possible to find positive serological markers. Typical images show pancreatic enlargement with focal or diffuse stenosis of the pancreatic duct but sometimes it presents as a focal pancreatic mass that is difficult to differentiate from pancreatic carcinoma. Aim: To report ten cases of autoimmune pancreatitis. Material and Methods: Retrospective review of clinical records of 10 patients aged 26 to 56 years (six males) with autoimmune pancreatitis. Results: The clinical presentation was obstructive jaundice in six cases, acute pancreatitis in two, persistent increase in serum amylase and Upase in one, and permanent abdominal pain and weight loss in one. On imaging studies, a circumscribed mass was founded in six patients. An endoscopic retrograde colangiopancreatography was performed in four patients showing an abnormal pancreatic duct in all. Six patients were operated and tissue for pathological study was obtained in five, showing inflammatory infiltration. Vive patients were treated with steroids with a good clinical response. Conclusions: Autoimmune pancreatitis must be borne in mind in the differential diagnosis of pancreatic lesions.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.3 20102010-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300006es10.4067/S0034-98872010000300006
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Autoimmunity
Pancreatitis, chronic
Prednisone
spellingShingle Autoimmunity
Pancreatitis, chronic
Prednisone
MUÑOZ C,SERGIO
MANCILLA A,CARLA
MOYANO S,LEONOR
CASTILLO T,CECILIA
ROSSI F,RICARDO
BRAHM B,JAVIER
BERGER F,ZOLTÁN
Pancreatitis autoinmune: Experiencia clínica y revisión de la literatura
description Background: Autoimmune pancreatitis is a special form of chronic pancreatitis, more common in men and usually presenting as obstructive jaundice or abdominal pain. It may be associated with other immunological disorders and sometimes it is possible to find positive serological markers. Typical images show pancreatic enlargement with focal or diffuse stenosis of the pancreatic duct but sometimes it presents as a focal pancreatic mass that is difficult to differentiate from pancreatic carcinoma. Aim: To report ten cases of autoimmune pancreatitis. Material and Methods: Retrospective review of clinical records of 10 patients aged 26 to 56 years (six males) with autoimmune pancreatitis. Results: The clinical presentation was obstructive jaundice in six cases, acute pancreatitis in two, persistent increase in serum amylase and Upase in one, and permanent abdominal pain and weight loss in one. On imaging studies, a circumscribed mass was founded in six patients. An endoscopic retrograde colangiopancreatography was performed in four patients showing an abnormal pancreatic duct in all. Six patients were operated and tissue for pathological study was obtained in five, showing inflammatory infiltration. Vive patients were treated with steroids with a good clinical response. Conclusions: Autoimmune pancreatitis must be borne in mind in the differential diagnosis of pancreatic lesions.
author MUÑOZ C,SERGIO
MANCILLA A,CARLA
MOYANO S,LEONOR
CASTILLO T,CECILIA
ROSSI F,RICARDO
BRAHM B,JAVIER
BERGER F,ZOLTÁN
author_facet MUÑOZ C,SERGIO
MANCILLA A,CARLA
MOYANO S,LEONOR
CASTILLO T,CECILIA
ROSSI F,RICARDO
BRAHM B,JAVIER
BERGER F,ZOLTÁN
author_sort MUÑOZ C,SERGIO
title Pancreatitis autoinmune: Experiencia clínica y revisión de la literatura
title_short Pancreatitis autoinmune: Experiencia clínica y revisión de la literatura
title_full Pancreatitis autoinmune: Experiencia clínica y revisión de la literatura
title_fullStr Pancreatitis autoinmune: Experiencia clínica y revisión de la literatura
title_full_unstemmed Pancreatitis autoinmune: Experiencia clínica y revisión de la literatura
title_sort pancreatitis autoinmune: experiencia clínica y revisión de la literatura
publisher Sociedad Médica de Santiago
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300006
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AT mancillaacarla pancreatitisautoinmuneexperienciaclinicayrevisiondelaliteratura
AT moyanosleonor pancreatitisautoinmuneexperienciaclinicayrevisiondelaliteratura
AT castillotcecilia pancreatitisautoinmuneexperienciaclinicayrevisiondelaliteratura
AT rossifricardo pancreatitisautoinmuneexperienciaclinicayrevisiondelaliteratura
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