Aportes de la epigenética en la comprensión del desarrollo del ser humano
Epigenetics refers to the study of how genes produce their effect on the phenotype of the organism. This article is a review on the scope and importance of recently discovered epigenetic mechanisms on human development and their relationship to perinatal epidemiological issues. It shows a general vi...
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Sociedad Médica de Santiago
2010
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oai:scielo:S0034-988720100003000182010-05-19Aportes de la epigenética en la comprensión del desarrollo del ser humanoBEDREGAL,PAULASHAND,BEATRIZSANTOS,MANUEL JVENTURA-JUNCÁ,PATRICIO Epigenesis, genetic Human development Phenotype Epigenetics refers to the study of how genes produce their effect on the phenotype of the organism. This article is a review on the scope and importance of recently discovered epigenetic mechanisms on human development and their relationship to perinatal epidemiological issues. It shows a general view and present concepts about epigenetics and its contribution to the comprehension of several physiologic and pathological conditions of human beings. Secondly, it analyzes the evidence coming from epidemiological and animal studies, about the influence of events that occur in the perinatal and early postnatal periods on adult life and the possible epigenetic mechanisms involved. Lastly, it underscores the implications ofthese results of future research and the design of public policies that take into account the importance of events in early life in thefuture development of individuals.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.3 20102010-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300018es10.4067/S0034-98872010000300018 |
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Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Epigenesis, genetic Human development Phenotype |
spellingShingle |
Epigenesis, genetic Human development Phenotype BEDREGAL,PAULA SHAND,BEATRIZ SANTOS,MANUEL J VENTURA-JUNCÁ,PATRICIO Aportes de la epigenética en la comprensión del desarrollo del ser humano |
description |
Epigenetics refers to the study of how genes produce their effect on the phenotype of the organism. This article is a review on the scope and importance of recently discovered epigenetic mechanisms on human development and their relationship to perinatal epidemiological issues. It shows a general view and present concepts about epigenetics and its contribution to the comprehension of several physiologic and pathological conditions of human beings. Secondly, it analyzes the evidence coming from epidemiological and animal studies, about the influence of events that occur in the perinatal and early postnatal periods on adult life and the possible epigenetic mechanisms involved. Lastly, it underscores the implications ofthese results of future research and the design of public policies that take into account the importance of events in early life in thefuture development of individuals. |
author |
BEDREGAL,PAULA SHAND,BEATRIZ SANTOS,MANUEL J VENTURA-JUNCÁ,PATRICIO |
author_facet |
BEDREGAL,PAULA SHAND,BEATRIZ SANTOS,MANUEL J VENTURA-JUNCÁ,PATRICIO |
author_sort |
BEDREGAL,PAULA |
title |
Aportes de la epigenética en la comprensión del desarrollo del ser humano |
title_short |
Aportes de la epigenética en la comprensión del desarrollo del ser humano |
title_full |
Aportes de la epigenética en la comprensión del desarrollo del ser humano |
title_fullStr |
Aportes de la epigenética en la comprensión del desarrollo del ser humano |
title_full_unstemmed |
Aportes de la epigenética en la comprensión del desarrollo del ser humano |
title_sort |
aportes de la epigenética en la comprensión del desarrollo del ser humano |
publisher |
Sociedad Médica de Santiago |
publishDate |
2010 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300018 |
work_keys_str_mv |
AT bedregalpaula aportesdelaepigeneticaenlacomprensiondeldesarrollodelserhumano AT shandbeatriz aportesdelaepigeneticaenlacomprensiondeldesarrollodelserhumano AT santosmanuelj aportesdelaepigeneticaenlacomprensiondeldesarrollodelserhumano AT venturajuncapatricio aportesdelaepigeneticaenlacomprensiondeldesarrollodelserhumano |
_version_ |
1718436496404381696 |