Aportes de la epigenética en la comprensión del desarrollo del ser humano

Epigenetics refers to the study of how genes produce their effect on the phenotype of the organism. This article is a review on the scope and importance of recently discovered epigenetic mechanisms on human development and their relationship to perinatal epidemiological issues. It shows a general vi...

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Autores principales: BEDREGAL,PAULA, SHAND,BEATRIZ, SANTOS,MANUEL J, VENTURA-JUNCÁ,PATRICIO
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2010
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300018
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spelling oai:scielo:S0034-988720100003000182010-05-19Aportes de la epigenética en la comprensión del desarrollo del ser humanoBEDREGAL,PAULASHAND,BEATRIZSANTOS,MANUEL JVENTURA-JUNCÁ,PATRICIO Epigenesis, genetic Human development Phenotype Epigenetics refers to the study of how genes produce their effect on the phenotype of the organism. This article is a review on the scope and importance of recently discovered epigenetic mechanisms on human development and their relationship to perinatal epidemiological issues. It shows a general view and present concepts about epigenetics and its contribution to the comprehension of several physiologic and pathological conditions of human beings. Secondly, it analyzes the evidence coming from epidemiological and animal studies, about the influence of events that occur in the perinatal and early postnatal periods on adult life and the possible epigenetic mechanisms involved. Lastly, it underscores the implications ofthese results of future research and the design of public policies that take into account the importance of events in early life in thefuture development of individuals.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.3 20102010-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300018es10.4067/S0034-98872010000300018
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Epigenesis, genetic
Human development
Phenotype
spellingShingle Epigenesis, genetic
Human development
Phenotype
BEDREGAL,PAULA
SHAND,BEATRIZ
SANTOS,MANUEL J
VENTURA-JUNCÁ,PATRICIO
Aportes de la epigenética en la comprensión del desarrollo del ser humano
description Epigenetics refers to the study of how genes produce their effect on the phenotype of the organism. This article is a review on the scope and importance of recently discovered epigenetic mechanisms on human development and their relationship to perinatal epidemiological issues. It shows a general view and present concepts about epigenetics and its contribution to the comprehension of several physiologic and pathological conditions of human beings. Secondly, it analyzes the evidence coming from epidemiological and animal studies, about the influence of events that occur in the perinatal and early postnatal periods on adult life and the possible epigenetic mechanisms involved. Lastly, it underscores the implications ofthese results of future research and the design of public policies that take into account the importance of events in early life in thefuture development of individuals.
author BEDREGAL,PAULA
SHAND,BEATRIZ
SANTOS,MANUEL J
VENTURA-JUNCÁ,PATRICIO
author_facet BEDREGAL,PAULA
SHAND,BEATRIZ
SANTOS,MANUEL J
VENTURA-JUNCÁ,PATRICIO
author_sort BEDREGAL,PAULA
title Aportes de la epigenética en la comprensión del desarrollo del ser humano
title_short Aportes de la epigenética en la comprensión del desarrollo del ser humano
title_full Aportes de la epigenética en la comprensión del desarrollo del ser humano
title_fullStr Aportes de la epigenética en la comprensión del desarrollo del ser humano
title_full_unstemmed Aportes de la epigenética en la comprensión del desarrollo del ser humano
title_sort aportes de la epigenética en la comprensión del desarrollo del ser humano
publisher Sociedad Médica de Santiago
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000300018
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