Neurotoxocariasis associated with lower motor neuron disease: Report of one case

We report a 51-year-old male with a history of palpitations, hepatopathy and hypercholesterolemia, who habitually ate raw goat meat, and developed general fasciculations, muscle cramps in the lower limbs, distal muscle weakness and wasting, without upper motor neuron signs or sensory abnormalities....

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Autores principales:	FINSTERER,JOSEF, KALLAB,VERENA, AUER,HERBERT
Lenguaje:	English
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Electromyography Motor neuron disease Neuromuscular diseases Toxocariasis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000400014
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spelling	oai:scielo:S0034-988720100004000142010-06-30Neurotoxocariasis associated with lower motor neuron disease: Report of one caseFINSTERER,JOSEFKALLAB,VERENAAUER,HERBERT Electromyography Motor neuron disease Neuromuscular diseases Toxocariasis We report a 51-year-old male with a history of palpitations, hepatopathy and hypercholesterolemia, who habitually ate raw goat meat, and developed general fasciculations, muscle cramps in the lower limbs, distal muscle weakness and wasting, without upper motor neuron signs or sensory abnormalities. Diagnostic workup revealed positive antibodies against Toxocara canis in the serum and cerebrospinal fuid. Nerve conduction studies revealed a proximal and distal axonal lesion of motor nerves and needle electromyography was indicative of acute and chronic denervation with giant motor unit action potentials. Despite a therapy with albendazole and riluzole, muscle weakness and wasting further progressed and affected also the respiratory muscles. Followup nerve conduction studies and electromyography confrmed progression of the axonal degeneration. Whether lower motor neuron disease was causally related to neurotoxocariasis or due to a general metabolic defect, remains speculative.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.4 20102010-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000400014en10.4067/S0034-98872010000400014
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Electromyography Motor neuron disease Neuromuscular diseases Toxocariasis
spellingShingle	Electromyography Motor neuron disease Neuromuscular diseases Toxocariasis FINSTERER,JOSEF KALLAB,VERENA AUER,HERBERT Neurotoxocariasis associated with lower motor neuron disease: Report of one case
description	We report a 51-year-old male with a history of palpitations, hepatopathy and hypercholesterolemia, who habitually ate raw goat meat, and developed general fasciculations, muscle cramps in the lower limbs, distal muscle weakness and wasting, without upper motor neuron signs or sensory abnormalities. Diagnostic workup revealed positive antibodies against Toxocara canis in the serum and cerebrospinal fuid. Nerve conduction studies revealed a proximal and distal axonal lesion of motor nerves and needle electromyography was indicative of acute and chronic denervation with giant motor unit action potentials. Despite a therapy with albendazole and riluzole, muscle weakness and wasting further progressed and affected also the respiratory muscles. Followup nerve conduction studies and electromyography confrmed progression of the axonal degeneration. Whether lower motor neuron disease was causally related to neurotoxocariasis or due to a general metabolic defect, remains speculative.
author	FINSTERER,JOSEF KALLAB,VERENA AUER,HERBERT
author_facet	FINSTERER,JOSEF KALLAB,VERENA AUER,HERBERT
author_sort	FINSTERER,JOSEF
title	Neurotoxocariasis associated with lower motor neuron disease: Report of one case
title_short	Neurotoxocariasis associated with lower motor neuron disease: Report of one case
title_full	Neurotoxocariasis associated with lower motor neuron disease: Report of one case
title_fullStr	Neurotoxocariasis associated with lower motor neuron disease: Report of one case
title_full_unstemmed	Neurotoxocariasis associated with lower motor neuron disease: Report of one case
title_sort	neurotoxocariasis associated with lower motor neuron disease: report of one case
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000400014
work_keys_str_mv	AT finstererjosef neurotoxocariasisassociatedwithlowermotorneurondiseasereportofonecase AT kallabverena neurotoxocariasisassociatedwithlowermotorneurondiseasereportofonecase AT auerherbert neurotoxocariasisassociatedwithlowermotorneurondiseasereportofonecase
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Neurotoxocariasis associated with lower motor neuron disease: Report of one case

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