38 Años de vigilancia epidemiológica de labio leporino y paladar hendido en la maternidad del Hospital Clínico de la Universidad de Chile

Background: Orofacial clefts are common and have a great medical and social importance. The Latin American Study of Congenital Malformations (ECLAMC), has maintained an epidemiological surveillance of congenital malformations since 1969, allowing the evaluation of trends in the prevalence of malform...

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Autores principales: NAZER H,JULIO, RAMÍREZ R,MARÍA CONSTANZA, CIFUENTES O,LUCÍA
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2010
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500006
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spelling oai:scielo:S0034-988720100005000062010-07-1238 Años de vigilancia epidemiológica de labio leporino y paladar hendido en la maternidad del Hospital Clínico de la Universidad de ChileNAZER H,JULIORAMÍREZ R,MARÍA CONSTANZACIFUENTES O,LUCÍA Cleft lip Congenital Abnormalities Genetics Background: Orofacial clefts are common and have a great medical and social importance. The Latin American Study of Congenital Malformations (ECLAMC), has maintained an epidemiological surveillance of congenital malformations since 1969, allowing the evaluation of trends in the prevalence of malformations. Aim: To evaluate the evolution curve of prevalence rates of orofacial clefts from 1971 to 2008. Material and Methods: All cases of orofacial clefts, occurring in newborns from the maternity of a university hospital from January 2000 to December 2008, were recorded as part of the ECLAMC. Historical information about the rates of the malformation between 1971 and 1999, was obtained from previous manuscripts of the authors. Results: In the study period, 15,635 children were born and 46 had cleft lip-palate (3‰). This rate is significantly higher than those observed previously, that fuctuated between 1.5 and 1.7‰. The prevalence rates of cleft lip remained stable from 1971 to 1999 and suffered a brisk and significant rise in the period 2000-2008 When the period is analyzed year by year, the increase in rates is observed in the last two years. The rates of cleft palate suffered a slight non significant rise until 2000. Conclusions: The increased rates of cleft lip palate observed in the last two years of the observation period may be a random result and should be monitored in the future.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.5 20102010-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500006es10.4067/S0034-98872010000500006
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Cleft lip
Congenital Abnormalities
Genetics
spellingShingle Cleft lip
Congenital Abnormalities
Genetics
NAZER H,JULIO
RAMÍREZ R,MARÍA CONSTANZA
CIFUENTES O,LUCÍA
38 Años de vigilancia epidemiológica de labio leporino y paladar hendido en la maternidad del Hospital Clínico de la Universidad de Chile
description Background: Orofacial clefts are common and have a great medical and social importance. The Latin American Study of Congenital Malformations (ECLAMC), has maintained an epidemiological surveillance of congenital malformations since 1969, allowing the evaluation of trends in the prevalence of malformations. Aim: To evaluate the evolution curve of prevalence rates of orofacial clefts from 1971 to 2008. Material and Methods: All cases of orofacial clefts, occurring in newborns from the maternity of a university hospital from January 2000 to December 2008, were recorded as part of the ECLAMC. Historical information about the rates of the malformation between 1971 and 1999, was obtained from previous manuscripts of the authors. Results: In the study period, 15,635 children were born and 46 had cleft lip-palate (3‰). This rate is significantly higher than those observed previously, that fuctuated between 1.5 and 1.7‰. The prevalence rates of cleft lip remained stable from 1971 to 1999 and suffered a brisk and significant rise in the period 2000-2008 When the period is analyzed year by year, the increase in rates is observed in the last two years. The rates of cleft palate suffered a slight non significant rise until 2000. Conclusions: The increased rates of cleft lip palate observed in the last two years of the observation period may be a random result and should be monitored in the future.
author NAZER H,JULIO
RAMÍREZ R,MARÍA CONSTANZA
CIFUENTES O,LUCÍA
author_facet NAZER H,JULIO
RAMÍREZ R,MARÍA CONSTANZA
CIFUENTES O,LUCÍA
author_sort NAZER H,JULIO
title 38 Años de vigilancia epidemiológica de labio leporino y paladar hendido en la maternidad del Hospital Clínico de la Universidad de Chile
title_short 38 Años de vigilancia epidemiológica de labio leporino y paladar hendido en la maternidad del Hospital Clínico de la Universidad de Chile
title_full 38 Años de vigilancia epidemiológica de labio leporino y paladar hendido en la maternidad del Hospital Clínico de la Universidad de Chile
title_fullStr 38 Años de vigilancia epidemiológica de labio leporino y paladar hendido en la maternidad del Hospital Clínico de la Universidad de Chile
title_full_unstemmed 38 Años de vigilancia epidemiológica de labio leporino y paladar hendido en la maternidad del Hospital Clínico de la Universidad de Chile
title_sort 38 años de vigilancia epidemiológica de labio leporino y paladar hendido en la maternidad del hospital clínico de la universidad de chile
publisher Sociedad Médica de Santiago
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500006
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AT ramirezrmariaconstanza 38anosdevigilanciaepidemiologicadelabioleporinoypaladarhendidoenlamaternidaddelhospitalclinicodelauniversidaddechile
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