Histoplasmosis oral localizada: Reporte de un caso clínico en Tucumán, Argentina

Histoplasmosis is an endemic deep mycosis produced by Histoplasma capsulatum, a dimorphic fungus. It penetrates into the organism by inhalation and spreads by lymphatic or hematic route. We report a 57-year-old immunocompetent male presenting with an enlargement of the tongue that also exhibited whi...

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Autores principales:	WIERNA,ALICIA, ANSONNAUD,ANA, SORIA,ANALÍA, GONZÁLEZ Mc D,MAURICIO
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Histoplasma Itraconazole Mycoses
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500009
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spelling	oai:scielo:S0034-988720100005000092010-07-12Histoplasmosis oral localizada: Reporte de un caso clínico en Tucumán, ArgentinaWIERNA,ALICIAANSONNAUD,ANASORIA,ANALÍAGONZÁLEZ Mc D,MAURICIO Histoplasma Itraconazole Mycoses Histoplasmosis is an endemic deep mycosis produced by Histoplasma capsulatum, a dimorphic fungus. It penetrates into the organism by inhalation and spreads by lymphatic or hematic route. We report a 57-year-old immunocompetent male presenting with an enlargement of the tongue that also exhibited white pseudomembranes. There were also nodular lesions in the dorsum of the tongue, separated by deep grooves. The pathological study revealed a chronic infammatory process with granulomas. The microbiological examination with the Giemsa technique showed multiple yeasts of 4-5 mm of diameter with a clear halo inside macrophages and epithelial cells, compatible with the parasitic phase of Histoplasma capsulatum. Serology was positive for the histoplasmine antigen. The patient was treated with Itraconazole 200 mg/day, experiencing 40% remission of lesions during the frst month of treatment.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.5 20102010-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500009es10.4067/S0034-98872010000500009
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Histoplasma Itraconazole Mycoses
spellingShingle	Histoplasma Itraconazole Mycoses WIERNA,ALICIA ANSONNAUD,ANA SORIA,ANALÍA GONZÁLEZ Mc D,MAURICIO Histoplasmosis oral localizada: Reporte de un caso clínico en Tucumán, Argentina
description	Histoplasmosis is an endemic deep mycosis produced by Histoplasma capsulatum, a dimorphic fungus. It penetrates into the organism by inhalation and spreads by lymphatic or hematic route. We report a 57-year-old immunocompetent male presenting with an enlargement of the tongue that also exhibited white pseudomembranes. There were also nodular lesions in the dorsum of the tongue, separated by deep grooves. The pathological study revealed a chronic infammatory process with granulomas. The microbiological examination with the Giemsa technique showed multiple yeasts of 4-5 mm of diameter with a clear halo inside macrophages and epithelial cells, compatible with the parasitic phase of Histoplasma capsulatum. Serology was positive for the histoplasmine antigen. The patient was treated with Itraconazole 200 mg/day, experiencing 40% remission of lesions during the frst month of treatment.
author	WIERNA,ALICIA ANSONNAUD,ANA SORIA,ANALÍA GONZÁLEZ Mc D,MAURICIO
author_facet	WIERNA,ALICIA ANSONNAUD,ANA SORIA,ANALÍA GONZÁLEZ Mc D,MAURICIO
author_sort	WIERNA,ALICIA
title	Histoplasmosis oral localizada: Reporte de un caso clínico en Tucumán, Argentina
title_short	Histoplasmosis oral localizada: Reporte de un caso clínico en Tucumán, Argentina
title_full	Histoplasmosis oral localizada: Reporte de un caso clínico en Tucumán, Argentina
title_fullStr	Histoplasmosis oral localizada: Reporte de un caso clínico en Tucumán, Argentina
title_full_unstemmed	Histoplasmosis oral localizada: Reporte de un caso clínico en Tucumán, Argentina
title_sort	histoplasmosis oral localizada: reporte de un caso clínico en tucumán, argentina
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500009
work_keys_str_mv	AT wiernaalicia histoplasmosisorallocalizadareportedeuncasoclinicoentucumanargentina AT ansonnaudana histoplasmosisorallocalizadareportedeuncasoclinicoentucumanargentina AT soriaanalia histoplasmosisorallocalizadareportedeuncasoclinicoentucumanargentina AT gonzalezmcdmauricio histoplasmosisorallocalizadareportedeuncasoclinicoentucumanargentina
_version_	1718436504991170560

Histoplasmosis oral localizada: Reporte de un caso clínico en Tucumán, Argentina

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