Atrofia vellositaria duodenal inducida por micofenolato mofetil: Caso clínico

Mycophenolate mofetil (MMF) is an immunosupressor agent frequently used in patients after bone marrow or solid organ transplants. The most common adverse reactions of the drug are gastrointestinal, specially diarrhea and vomiting. We report a 53-year-old male, that received a heart transplant receiv...

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Autores principales:	TAPIA E,OSCAR, VILLASECA H,MIGUEL, SIERRALTA Z,ARMANDO, ROA S,JUAN CARLOS
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Diarrhea Immunosuppressive agents Mycophenolate mofetil
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500010
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spelling	oai:scielo:S0034-988720100005000102010-07-12Atrofia vellositaria duodenal inducida por micofenolato mofetil: Caso clínicoTAPIA E,OSCARVILLASECA H,MIGUELSIERRALTA Z,ARMANDOROA S,JUAN CARLOS Diarrhea Immunosuppressive agents Mycophenolate mofetil Mycophenolate mofetil (MMF) is an immunosupressor agent frequently used in patients after bone marrow or solid organ transplants. The most common adverse reactions of the drug are gastrointestinal, specially diarrhea and vomiting. We report a 53-year-old male, that received a heart transplant receiving immunosuppression with cyclosporine, mycophenolate mofetil and prednisone. Six months after the transplant, the patient started with diarrhea, anorexia and weight loss. A duodenal biopsy showed villous atrophy. Celiac disease and the presence of parasites were discarded. Mycophenolate mofetil was discontinued and one week later, diarrhea subsided. Two months later the patient was asymptomatic and recovered weight. A new duodenal biopsy showed absence of villous atrophy.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.5 20102010-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500010es10.4067/S0034-98872010000500010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Diarrhea Immunosuppressive agents Mycophenolate mofetil
spellingShingle	Diarrhea Immunosuppressive agents Mycophenolate mofetil TAPIA E,OSCAR VILLASECA H,MIGUEL SIERRALTA Z,ARMANDO ROA S,JUAN CARLOS Atrofia vellositaria duodenal inducida por micofenolato mofetil: Caso clínico
description	Mycophenolate mofetil (MMF) is an immunosupressor agent frequently used in patients after bone marrow or solid organ transplants. The most common adverse reactions of the drug are gastrointestinal, specially diarrhea and vomiting. We report a 53-year-old male, that received a heart transplant receiving immunosuppression with cyclosporine, mycophenolate mofetil and prednisone. Six months after the transplant, the patient started with diarrhea, anorexia and weight loss. A duodenal biopsy showed villous atrophy. Celiac disease and the presence of parasites were discarded. Mycophenolate mofetil was discontinued and one week later, diarrhea subsided. Two months later the patient was asymptomatic and recovered weight. A new duodenal biopsy showed absence of villous atrophy.
author	TAPIA E,OSCAR VILLASECA H,MIGUEL SIERRALTA Z,ARMANDO ROA S,JUAN CARLOS
author_facet	TAPIA E,OSCAR VILLASECA H,MIGUEL SIERRALTA Z,ARMANDO ROA S,JUAN CARLOS
author_sort	TAPIA E,OSCAR
title	Atrofia vellositaria duodenal inducida por micofenolato mofetil: Caso clínico
title_short	Atrofia vellositaria duodenal inducida por micofenolato mofetil: Caso clínico
title_full	Atrofia vellositaria duodenal inducida por micofenolato mofetil: Caso clínico
title_fullStr	Atrofia vellositaria duodenal inducida por micofenolato mofetil: Caso clínico
title_full_unstemmed	Atrofia vellositaria duodenal inducida por micofenolato mofetil: Caso clínico
title_sort	atrofia vellositaria duodenal inducida por micofenolato mofetil: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500010
work_keys_str_mv	AT tapiaeoscar atrofiavellositariaduodenalinducidapormicofenolatomofetilcasoclinico AT villasecahmiguel atrofiavellositariaduodenalinducidapormicofenolatomofetilcasoclinico AT sierraltazarmando atrofiavellositariaduodenalinducidapormicofenolatomofetilcasoclinico AT roasjuancarlos atrofiavellositariaduodenalinducidapormicofenolatomofetilcasoclinico
_version_	1718436505183059968

Atrofia vellositaria duodenal inducida por micofenolato mofetil: Caso clínico

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