La aspergilosis pulmonar invasiva en la enfermedad pulmonar obstructiva crónica

Invasive pulmonary aspergillosis (IPA) is a severe disease, specially among immunocompromised patients. Its frequency increases in other patients such as those with Chronic Obstructive Pulmonary Disease (COPD), mainly when steroids are prescribed. The most common form of presentation is a respirator...

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Autores principales: VALLE,JOSÉ MANUEL, GONZÁLEZ-BARCALA,FRANCISCO JAVIER, ÁLVAREZ-DOBAÑO,JOSÉ MANUEL, VALDÉS C,LUIS
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2010
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500013
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spelling oai:scielo:S0034-988720100005000132010-07-12La aspergilosis pulmonar invasiva en la enfermedad pulmonar obstructiva crónicaVALLE,JOSÉ MANUELGONZÁLEZ-BARCALA,FRANCISCO JAVIERÁLVAREZ-DOBAÑO,JOSÉ MANUELVALDÉS C,LUIS Aspergillosis Chronic obstructive Immunity Pulmonary disease Invasive pulmonary aspergillosis (IPA) is a severe disease, specially among immunocompromised patients. Its frequency increases in other patients such as those with Chronic Obstructive Pulmonary Disease (COPD), mainly when steroids are prescribed. The most common form of presentation is a respiratory tract infection with poor response to antimicrobial treatment. The delay in its diagnosis is one of the main causes of its high lethality. Once suspected, respiratory secretion cultures, chest X ray examination and computed tomography should be obtained and galactomannan, a marker of hematogenous dissemination of the microorganism, should be determined. Although the repeated isolation of Aspergillus spp is suggestive of invasive disease, the definitive diagnosis requires cytopathological confirmation. Further studies should be performed in these patients, since the available information was obtained from the observations made in immunocompromised patients, and may not be applicable accurately to API among COPD patients.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.5 20102010-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500013es10.4067/S0034-98872010000500013
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Aspergillosis
Chronic obstructive
Immunity
Pulmonary disease
spellingShingle Aspergillosis
Chronic obstructive
Immunity
Pulmonary disease
VALLE,JOSÉ MANUEL
GONZÁLEZ-BARCALA,FRANCISCO JAVIER
ÁLVAREZ-DOBAÑO,JOSÉ MANUEL
VALDÉS C,LUIS
La aspergilosis pulmonar invasiva en la enfermedad pulmonar obstructiva crónica
description Invasive pulmonary aspergillosis (IPA) is a severe disease, specially among immunocompromised patients. Its frequency increases in other patients such as those with Chronic Obstructive Pulmonary Disease (COPD), mainly when steroids are prescribed. The most common form of presentation is a respiratory tract infection with poor response to antimicrobial treatment. The delay in its diagnosis is one of the main causes of its high lethality. Once suspected, respiratory secretion cultures, chest X ray examination and computed tomography should be obtained and galactomannan, a marker of hematogenous dissemination of the microorganism, should be determined. Although the repeated isolation of Aspergillus spp is suggestive of invasive disease, the definitive diagnosis requires cytopathological confirmation. Further studies should be performed in these patients, since the available information was obtained from the observations made in immunocompromised patients, and may not be applicable accurately to API among COPD patients.
author VALLE,JOSÉ MANUEL
GONZÁLEZ-BARCALA,FRANCISCO JAVIER
ÁLVAREZ-DOBAÑO,JOSÉ MANUEL
VALDÉS C,LUIS
author_facet VALLE,JOSÉ MANUEL
GONZÁLEZ-BARCALA,FRANCISCO JAVIER
ÁLVAREZ-DOBAÑO,JOSÉ MANUEL
VALDÉS C,LUIS
author_sort VALLE,JOSÉ MANUEL
title La aspergilosis pulmonar invasiva en la enfermedad pulmonar obstructiva crónica
title_short La aspergilosis pulmonar invasiva en la enfermedad pulmonar obstructiva crónica
title_full La aspergilosis pulmonar invasiva en la enfermedad pulmonar obstructiva crónica
title_fullStr La aspergilosis pulmonar invasiva en la enfermedad pulmonar obstructiva crónica
title_full_unstemmed La aspergilosis pulmonar invasiva en la enfermedad pulmonar obstructiva crónica
title_sort la aspergilosis pulmonar invasiva en la enfermedad pulmonar obstructiva crónica
publisher Sociedad Médica de Santiago
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000500013
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