Colesterolosis y cáncer de la vesícula biliar

Background: Cholesterolosis is frequently observed in cholecystectomies performed for lithiasis or chronic cholecystitis. Aim: To determine the degree of association between cholesterolosis and gallbladder cancer. Material and Methods: In a prospective study of gallbladder cancer, all gallbladders o...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	ROA E,IVÁN, DE ARETXABALA U,XABIER, IBACACHE S,GILDA, MUÑOZ N,SERGIO
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Cholelithiasis Cholecystectomy Gallbladder neoplasms
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700002
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872010000700002
record_format	dspace
spelling	oai:scielo:S0034-988720100007000022010-11-26Colesterolosis y cáncer de la vesícula biliarROA E,IVÁNDE ARETXABALA U,XABIERIBACACHE S,GILDAMUÑOZ N,SERGIO Cholelithiasis Cholecystectomy Gallbladder neoplasms Background: Cholesterolosis is frequently observed in cholecystectomies performed for lithiasis or chronic cholecystitis. Aim: To determine the degree of association between cholesterolosis and gallbladder cancer. Material and Methods: In a prospective study of gallbladder cancer, all gallbladders obtained during cholecystectomies were processed for pathological study, following a special protocol. As part of this study, 23304 surgical samples obtained between 1993 and 2002 were studied, looking for a relationship between cholesterolosis and chronic cholecystitis, adenomas, dysplasia and gallbladder cancer. Results: Seventy nine percent of patients were women. Cholesterolosis was observed in 3,123 cases (13.4%). Cholesterolosis was more common in women (14.2%) than in men (10.2%) (p < 0.001). In the same period, 29 patients were diagnosed with adenomas (0.12%), 179 cases with dysplasia not associated with gallbladder cancer (0.8%) and 739 gallbladder cancer (3.2%). The frequency of cholesterolosis was 13.8% in chronic cholecystitis, 13.7% in adenomas, 12.1% in dysplasias and 1.35% in patients with gallbladder cancer (p < 0.01). Of the thirteen cases with gallbladder cancer and cholesterolosis, 10 were early gallbladder carcinomas. Patients with cholesterolosis were 9.2 times less likely to have cancer than those who did not have cholesterolosis. Conclusions: Cholesterolosis has a strong negative association with gallbladder cancer.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.7 20102010-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700002es10.4067/S0034-98872010000700002
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Cholelithiasis Cholecystectomy Gallbladder neoplasms
spellingShingle	Cholelithiasis Cholecystectomy Gallbladder neoplasms ROA E,IVÁN DE ARETXABALA U,XABIER IBACACHE S,GILDA MUÑOZ N,SERGIO Colesterolosis y cáncer de la vesícula biliar
description	Background: Cholesterolosis is frequently observed in cholecystectomies performed for lithiasis or chronic cholecystitis. Aim: To determine the degree of association between cholesterolosis and gallbladder cancer. Material and Methods: In a prospective study of gallbladder cancer, all gallbladders obtained during cholecystectomies were processed for pathological study, following a special protocol. As part of this study, 23304 surgical samples obtained between 1993 and 2002 were studied, looking for a relationship between cholesterolosis and chronic cholecystitis, adenomas, dysplasia and gallbladder cancer. Results: Seventy nine percent of patients were women. Cholesterolosis was observed in 3,123 cases (13.4%). Cholesterolosis was more common in women (14.2%) than in men (10.2%) (p < 0.001). In the same period, 29 patients were diagnosed with adenomas (0.12%), 179 cases with dysplasia not associated with gallbladder cancer (0.8%) and 739 gallbladder cancer (3.2%). The frequency of cholesterolosis was 13.8% in chronic cholecystitis, 13.7% in adenomas, 12.1% in dysplasias and 1.35% in patients with gallbladder cancer (p < 0.01). Of the thirteen cases with gallbladder cancer and cholesterolosis, 10 were early gallbladder carcinomas. Patients with cholesterolosis were 9.2 times less likely to have cancer than those who did not have cholesterolosis. Conclusions: Cholesterolosis has a strong negative association with gallbladder cancer.
author	ROA E,IVÁN DE ARETXABALA U,XABIER IBACACHE S,GILDA MUÑOZ N,SERGIO
author_facet	ROA E,IVÁN DE ARETXABALA U,XABIER IBACACHE S,GILDA MUÑOZ N,SERGIO
author_sort	ROA E,IVÁN
title	Colesterolosis y cáncer de la vesícula biliar
title_short	Colesterolosis y cáncer de la vesícula biliar
title_full	Colesterolosis y cáncer de la vesícula biliar
title_fullStr	Colesterolosis y cáncer de la vesícula biliar
title_full_unstemmed	Colesterolosis y cáncer de la vesícula biliar
title_sort	colesterolosis y cáncer de la vesícula biliar
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700002
work_keys_str_mv	AT roaeivan colesterolosisycancerdelavesiculabiliar AT dearetxabalauxabier colesterolosisycancerdelavesiculabiliar AT ibacachesgilda colesterolosisycancerdelavesiculabiliar AT munoznsergio colesterolosisycancerdelavesiculabiliar
_version_	1718436513510850560

Colesterolosis y cáncer de la vesícula biliar

Ejemplares similares