Elevada seroprevalencia de citomegalovirus, virus herpes simplex tipo 1 y virus Epstein Barr en adultos con virus de la inmunodeficiencia humana

Background: Cytomegalovirus (CMV), herpes simplex type 1 (HSV-1) and Epstein Barr virus (EBV) are latent persistent infections. Their reactivation may cause illnesses and death in human immunodefciency virus-infected (HIV) people. World wide seroprevalence of these viruses is over 50%. In Chile, inf...

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Autores principales: LUCHSINGER,VIVIAN, LUZORO,AMARANTA, MARTÍNEZ,MARÍA JOSÉ
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2010
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HIV
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700003
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spelling oai:scielo:S0034-988720100007000032010-11-26Elevada seroprevalencia de citomegalovirus, virus herpes simplex tipo 1 y virus Epstein Barr en adultos con virus de la inmunodeficiencia humanaLUCHSINGER,VIVIANLUZORO,AMARANTAMARTÍNEZ,MARÍA JOSÉ Cytomegalovirus Herpesvirus 1 human Herpesvirus 4 human HIV Background: Cytomegalovirus (CMV), herpes simplex type 1 (HSV-1) and Epstein Barr virus (EBV) are latent persistent infections. Their reactivation may cause illnesses and death in human immunodefciency virus-infected (HIV) people. World wide seroprevalence of these viruses is over 50%. In Chile, information is not available. Aim: To determine the seroprevalence of CMV, HSV-1 and EBV in Chilean HIV-infected adults. Patients and Methods: A total of 400 HIV- infected adults aged 17 to 67 years (340 males) were studied during 2005 and 2006. CMV, HSV-1 and EBV serum antibodies were measured by enzyme-linked immunoabsorbent assay. Results: The mean lapse from the diagnosis of HIV and serum testing was 67 months and 69.5% patients received antiretroviral therapy. Sixty seven percent of the sample were men who had sex with men (MSM). The seroprevalence for CMV, HSV-1 and EBV were 98.5, 92.2 and 99.7%, respectively. No patient had negative antibodies for all three viruses. Male patients that were negative for HSV-1 had a lower frequency of MSM than the rest of males (26% vs 62%, p < 0.01). Conclusions: There is a high prevalence of positive antibodies against CMV, HSV-1 and EBV in Chilean adults infected with HIV. Specifc diagnostic tests and antiviral therapy should be available for these patients.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.7 20102010-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700003es10.4067/S0034-98872010000700003
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Cytomegalovirus
Herpesvirus 1
human
Herpesvirus 4
human
HIV
spellingShingle Cytomegalovirus
Herpesvirus 1
human
Herpesvirus 4
human
HIV
LUCHSINGER,VIVIAN
LUZORO,AMARANTA
MARTÍNEZ,MARÍA JOSÉ
Elevada seroprevalencia de citomegalovirus, virus herpes simplex tipo 1 y virus Epstein Barr en adultos con virus de la inmunodeficiencia humana
description Background: Cytomegalovirus (CMV), herpes simplex type 1 (HSV-1) and Epstein Barr virus (EBV) are latent persistent infections. Their reactivation may cause illnesses and death in human immunodefciency virus-infected (HIV) people. World wide seroprevalence of these viruses is over 50%. In Chile, information is not available. Aim: To determine the seroprevalence of CMV, HSV-1 and EBV in Chilean HIV-infected adults. Patients and Methods: A total of 400 HIV- infected adults aged 17 to 67 years (340 males) were studied during 2005 and 2006. CMV, HSV-1 and EBV serum antibodies were measured by enzyme-linked immunoabsorbent assay. Results: The mean lapse from the diagnosis of HIV and serum testing was 67 months and 69.5% patients received antiretroviral therapy. Sixty seven percent of the sample were men who had sex with men (MSM). The seroprevalence for CMV, HSV-1 and EBV were 98.5, 92.2 and 99.7%, respectively. No patient had negative antibodies for all three viruses. Male patients that were negative for HSV-1 had a lower frequency of MSM than the rest of males (26% vs 62%, p < 0.01). Conclusions: There is a high prevalence of positive antibodies against CMV, HSV-1 and EBV in Chilean adults infected with HIV. Specifc diagnostic tests and antiviral therapy should be available for these patients.
author LUCHSINGER,VIVIAN
LUZORO,AMARANTA
MARTÍNEZ,MARÍA JOSÉ
author_facet LUCHSINGER,VIVIAN
LUZORO,AMARANTA
MARTÍNEZ,MARÍA JOSÉ
author_sort LUCHSINGER,VIVIAN
title Elevada seroprevalencia de citomegalovirus, virus herpes simplex tipo 1 y virus Epstein Barr en adultos con virus de la inmunodeficiencia humana
title_short Elevada seroprevalencia de citomegalovirus, virus herpes simplex tipo 1 y virus Epstein Barr en adultos con virus de la inmunodeficiencia humana
title_full Elevada seroprevalencia de citomegalovirus, virus herpes simplex tipo 1 y virus Epstein Barr en adultos con virus de la inmunodeficiencia humana
title_fullStr Elevada seroprevalencia de citomegalovirus, virus herpes simplex tipo 1 y virus Epstein Barr en adultos con virus de la inmunodeficiencia humana
title_full_unstemmed Elevada seroprevalencia de citomegalovirus, virus herpes simplex tipo 1 y virus Epstein Barr en adultos con virus de la inmunodeficiencia humana
title_sort elevada seroprevalencia de citomegalovirus, virus herpes simplex tipo 1 y virus epstein barr en adultos con virus de la inmunodeficiencia humana
publisher Sociedad Médica de Santiago
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700003
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