Tiroiditis crónica de Hashimoto: Serie clínica

Background: Chronic Hashimoto Thyroiditis (CHT) is the main cause of hypothyroidism. Aim: To report a series of patients with CHT. Material and Methods: Retrospective analysis of a series of 27 men aged 38 ± 14 years and 201 women aged 37 ± 16 years, evaluated in the private offces of two of the aut...

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Autores principales: PIRAINO N,PATRICIA, SEPÚLVEDA N,ANDREA, CAVADA CH,GABRIEL
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2010
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700006
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spelling oai:scielo:S0034-988720100007000062010-11-26Tiroiditis crónica de Hashimoto: Serie clínicaPIRAINO N,PATRICIASEPÚLVEDA N,ANDREACAVADA CH,GABRIEL Hashimoto disease Hypothyroidism Thyrotropin Background: Chronic Hashimoto Thyroiditis (CHT) is the main cause of hypothyroidism. Aim: To report a series of patients with CHT. Material and Methods: Retrospective analysis of a series of 27 men aged 38 ± 14 years and 201 women aged 37 ± 16 years, evaluated in the private offces of two of the authors. Results: Fifty six percent of patients only had unspecifc symptoms at the moment of consultation, 50% had a family history of thyroid diseases and only 21% of women had a previous history of goiter. Eighty one percent of patients had clinical or subclinical hypothyroidism, 62% had both antithyroglobulin and antithyroid peroxidase positive antibodies and 13% had both antibodies negative. Only 1.4% of patients had a normal thyroid ultrasound examination. Patients were treated with levothyroxine at a mean dosage of 75 µg/day and 53% achieved an adequate TSH level. Six of ten patients operated due to nodules had a papillary carcinoma. Conclusions: CHT should be sought in the general population, especially those with a family history of thyroid disease. Thyroid ultrasound is seldom normal in patients with CHT. Thyroid substitution should be monitored periodically to achieve adequate TSH levels.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.7 20102010-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700006es10.4067/S0034-98872010000700006
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Hashimoto disease
Hypothyroidism
Thyrotropin
spellingShingle Hashimoto disease
Hypothyroidism
Thyrotropin
PIRAINO N,PATRICIA
SEPÚLVEDA N,ANDREA
CAVADA CH,GABRIEL
Tiroiditis crónica de Hashimoto: Serie clínica
description Background: Chronic Hashimoto Thyroiditis (CHT) is the main cause of hypothyroidism. Aim: To report a series of patients with CHT. Material and Methods: Retrospective analysis of a series of 27 men aged 38 ± 14 years and 201 women aged 37 ± 16 years, evaluated in the private offces of two of the authors. Results: Fifty six percent of patients only had unspecifc symptoms at the moment of consultation, 50% had a family history of thyroid diseases and only 21% of women had a previous history of goiter. Eighty one percent of patients had clinical or subclinical hypothyroidism, 62% had both antithyroglobulin and antithyroid peroxidase positive antibodies and 13% had both antibodies negative. Only 1.4% of patients had a normal thyroid ultrasound examination. Patients were treated with levothyroxine at a mean dosage of 75 µg/day and 53% achieved an adequate TSH level. Six of ten patients operated due to nodules had a papillary carcinoma. Conclusions: CHT should be sought in the general population, especially those with a family history of thyroid disease. Thyroid ultrasound is seldom normal in patients with CHT. Thyroid substitution should be monitored periodically to achieve adequate TSH levels.
author PIRAINO N,PATRICIA
SEPÚLVEDA N,ANDREA
CAVADA CH,GABRIEL
author_facet PIRAINO N,PATRICIA
SEPÚLVEDA N,ANDREA
CAVADA CH,GABRIEL
author_sort PIRAINO N,PATRICIA
title Tiroiditis crónica de Hashimoto: Serie clínica
title_short Tiroiditis crónica de Hashimoto: Serie clínica
title_full Tiroiditis crónica de Hashimoto: Serie clínica
title_fullStr Tiroiditis crónica de Hashimoto: Serie clínica
title_full_unstemmed Tiroiditis crónica de Hashimoto: Serie clínica
title_sort tiroiditis crónica de hashimoto: serie clínica
publisher Sociedad Médica de Santiago
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700006
work_keys_str_mv AT pirainonpatricia tiroiditiscronicadehashimotoserieclinica
AT sepulvedanandrea tiroiditiscronicadehashimotoserieclinica
AT cavadachgabriel tiroiditiscronicadehashimotoserieclinica
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