Fortificación de la harina de trigo con ácido fólico en Chile: Consecuencias no intencionadas

Background: High daily intake of folic acid (FA) could determine health risks in some populations. Aim: To review the Chilean FA wheat four fortifcation and to identify the existence of populations at risk. Material and Methods: We categorized the FA levels in four samples (percentil P) (2005-2008)...

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Autores principales: CASTILLO L,CECILIA, TUR,JOSEP A, UAUY,RICARDO
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2010
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700007
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spelling oai:scielo:S0034-988720100007000072010-11-26Fortificación de la harina de trigo con ácido fólico en Chile: Consecuencias no intencionadasCASTILLO L,CECILIATUR,JOSEP AUAUY,RICARDO Folates folic acid fortifed food risk assessment Background: High daily intake of folic acid (FA) could determine health risks in some populations. Aim: To review the Chilean FA wheat four fortifcation and to identify the existence of populations at risk. Material and Methods: We categorized the FA levels in four samples (percentil P) (2005-2008) and estimated intake of FA (mg/d) in adults from apparent bread consumption according to different levels (P20, 50 and 95) and children consumption (8-13 years) considering socioeconomic status (SES), bread/g/d intake (P20, 50 and 75) and regulated level of four fortifcation (2.2 mg FA/100 g). Daily Dietary Folate Equivalent (DFE) consumption was estimated from serum folate in adults and elderly people (both sexes). We calculated the percentage of population with FA intakes over the estimated average requirement (EAR) and maximum level (UL) pre and post-fortifcation. Results: There is great variability in FA four: 10-20% samples without FA and 10-30% with levels > 2.2 mg/100 g. Adult daily consumption (2-4 day/loaves) could determine FA intakes close to UL. Children daily bread consumption (low socioeconomic level) > P75 have intakes close to UL. Post-fortifcation estimated daily DFE from serum folate in women, men and elderly people show: 99% of women, 100% of men and the elderly people have intakes higher than EAR. Additionally 2.3% of women and 6% of men would have intakes near the UL. Conclusions: The four FA levels and serum folate levels in some populations show increased FA post-fortifcation intakes, which could lead to greater risk suggesting a revision of the fortifcation level.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.7 20102010-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700007es10.4067/S0034-98872010000700007
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Folates
folic acid
fortifed food
risk assessment
spellingShingle Folates
folic acid
fortifed food
risk assessment
CASTILLO L,CECILIA
TUR,JOSEP A
UAUY,RICARDO
Fortificación de la harina de trigo con ácido fólico en Chile: Consecuencias no intencionadas
description Background: High daily intake of folic acid (FA) could determine health risks in some populations. Aim: To review the Chilean FA wheat four fortifcation and to identify the existence of populations at risk. Material and Methods: We categorized the FA levels in four samples (percentil P) (2005-2008) and estimated intake of FA (mg/d) in adults from apparent bread consumption according to different levels (P20, 50 and 95) and children consumption (8-13 years) considering socioeconomic status (SES), bread/g/d intake (P20, 50 and 75) and regulated level of four fortifcation (2.2 mg FA/100 g). Daily Dietary Folate Equivalent (DFE) consumption was estimated from serum folate in adults and elderly people (both sexes). We calculated the percentage of population with FA intakes over the estimated average requirement (EAR) and maximum level (UL) pre and post-fortifcation. Results: There is great variability in FA four: 10-20% samples without FA and 10-30% with levels > 2.2 mg/100 g. Adult daily consumption (2-4 day/loaves) could determine FA intakes close to UL. Children daily bread consumption (low socioeconomic level) > P75 have intakes close to UL. Post-fortifcation estimated daily DFE from serum folate in women, men and elderly people show: 99% of women, 100% of men and the elderly people have intakes higher than EAR. Additionally 2.3% of women and 6% of men would have intakes near the UL. Conclusions: The four FA levels and serum folate levels in some populations show increased FA post-fortifcation intakes, which could lead to greater risk suggesting a revision of the fortifcation level.
author CASTILLO L,CECILIA
TUR,JOSEP A
UAUY,RICARDO
author_facet CASTILLO L,CECILIA
TUR,JOSEP A
UAUY,RICARDO
author_sort CASTILLO L,CECILIA
title Fortificación de la harina de trigo con ácido fólico en Chile: Consecuencias no intencionadas
title_short Fortificación de la harina de trigo con ácido fólico en Chile: Consecuencias no intencionadas
title_full Fortificación de la harina de trigo con ácido fólico en Chile: Consecuencias no intencionadas
title_fullStr Fortificación de la harina de trigo con ácido fólico en Chile: Consecuencias no intencionadas
title_full_unstemmed Fortificación de la harina de trigo con ácido fólico en Chile: Consecuencias no intencionadas
title_sort fortificación de la harina de trigo con ácido fólico en chile: consecuencias no intencionadas
publisher Sociedad Médica de Santiago
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700007
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AT turjosepa fortificaciondelaharinadetrigoconacidofolicoenchileconsecuenciasnointencionadas
AT uauyricardo fortificaciondelaharinadetrigoconacidofolicoenchileconsecuenciasnointencionadas
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