Rol del riñón en la hipertensión sal-sensible

An important proportion of patients with essential hypertension are salt sensitive, defined as those who experience signifcant blood pressure changes according to the amount of salt intake. They have a disturbance in the pressure induced natriuresis mechanism and their kidneys have functional and mo...

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Autores principales: ARDILES,LEOPOLDO, MEZZANO,SERGIO
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2010
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700012
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spelling oai:scielo:S0034-988720100007000122010-11-26Rol del riñón en la hipertensión sal-sensibleARDILES,LEOPOLDOMEZZANO,SERGIO Hypertension, renal Kidney diseases Natriuresis An important proportion of patients with essential hypertension are salt sensitive, defined as those who experience signifcant blood pressure changes according to the amount of salt intake. They have a disturbance in the pressure induced natriuresis mechanism and their kidneys have functional and morphological alterations con-sistent with an acquired tubulointerstitial alteration, afferent arteriole damage and alteration of peritubular capillaries. All these alterations lead to disturbances in sodium load excretion under normal pressures. There is also an associated activation of kidney vasoconstrictor/salt retaining systems and a reduction in the vasodilator/ salt eliminating mechanisms. These alterations, that originate early in life, generate a new blood pressure level, that corrects natriuresis at the expense of a sustained hypertension.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.7 20102010-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700012es10.4067/S0034-98872010000700012
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Hypertension, renal
Kidney diseases
Natriuresis
spellingShingle Hypertension, renal
Kidney diseases
Natriuresis
ARDILES,LEOPOLDO
MEZZANO,SERGIO
Rol del riñón en la hipertensión sal-sensible
description An important proportion of patients with essential hypertension are salt sensitive, defined as those who experience signifcant blood pressure changes according to the amount of salt intake. They have a disturbance in the pressure induced natriuresis mechanism and their kidneys have functional and morphological alterations con-sistent with an acquired tubulointerstitial alteration, afferent arteriole damage and alteration of peritubular capillaries. All these alterations lead to disturbances in sodium load excretion under normal pressures. There is also an associated activation of kidney vasoconstrictor/salt retaining systems and a reduction in the vasodilator/ salt eliminating mechanisms. These alterations, that originate early in life, generate a new blood pressure level, that corrects natriuresis at the expense of a sustained hypertension.
author ARDILES,LEOPOLDO
MEZZANO,SERGIO
author_facet ARDILES,LEOPOLDO
MEZZANO,SERGIO
author_sort ARDILES,LEOPOLDO
title Rol del riñón en la hipertensión sal-sensible
title_short Rol del riñón en la hipertensión sal-sensible
title_full Rol del riñón en la hipertensión sal-sensible
title_fullStr Rol del riñón en la hipertensión sal-sensible
title_full_unstemmed Rol del riñón en la hipertensión sal-sensible
title_sort rol del riñón en la hipertensión sal-sensible
publisher Sociedad Médica de Santiago
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700012
work_keys_str_mv AT ardilesleopoldo roldelrinonenlahipertensionsalsensible
AT mezzanosergio roldelrinonenlahipertensionsalsensible
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