Rol del riñón en la hipertensión sal-sensible
An important proportion of patients with essential hypertension are salt sensitive, defined as those who experience signifcant blood pressure changes according to the amount of salt intake. They have a disturbance in the pressure induced natriuresis mechanism and their kidneys have functional and mo...
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Sociedad Médica de Santiago
2010
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oai:scielo:S0034-988720100007000122010-11-26Rol del riñón en la hipertensión sal-sensibleARDILES,LEOPOLDOMEZZANO,SERGIO Hypertension, renal Kidney diseases Natriuresis An important proportion of patients with essential hypertension are salt sensitive, defined as those who experience signifcant blood pressure changes according to the amount of salt intake. They have a disturbance in the pressure induced natriuresis mechanism and their kidneys have functional and morphological alterations con-sistent with an acquired tubulointerstitial alteration, afferent arteriole damage and alteration of peritubular capillaries. All these alterations lead to disturbances in sodium load excretion under normal pressures. There is also an associated activation of kidney vasoconstrictor/salt retaining systems and a reduction in the vasodilator/ salt eliminating mechanisms. These alterations, that originate early in life, generate a new blood pressure level, that corrects natriuresis at the expense of a sustained hypertension.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.7 20102010-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700012es10.4067/S0034-98872010000700012 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Hypertension, renal Kidney diseases Natriuresis |
spellingShingle |
Hypertension, renal Kidney diseases Natriuresis ARDILES,LEOPOLDO MEZZANO,SERGIO Rol del riñón en la hipertensión sal-sensible |
description |
An important proportion of patients with essential hypertension are salt sensitive, defined as those who experience signifcant blood pressure changes according to the amount of salt intake. They have a disturbance in the pressure induced natriuresis mechanism and their kidneys have functional and morphological alterations con-sistent with an acquired tubulointerstitial alteration, afferent arteriole damage and alteration of peritubular capillaries. All these alterations lead to disturbances in sodium load excretion under normal pressures. There is also an associated activation of kidney vasoconstrictor/salt retaining systems and a reduction in the vasodilator/ salt eliminating mechanisms. These alterations, that originate early in life, generate a new blood pressure level, that corrects natriuresis at the expense of a sustained hypertension. |
author |
ARDILES,LEOPOLDO MEZZANO,SERGIO |
author_facet |
ARDILES,LEOPOLDO MEZZANO,SERGIO |
author_sort |
ARDILES,LEOPOLDO |
title |
Rol del riñón en la hipertensión sal-sensible |
title_short |
Rol del riñón en la hipertensión sal-sensible |
title_full |
Rol del riñón en la hipertensión sal-sensible |
title_fullStr |
Rol del riñón en la hipertensión sal-sensible |
title_full_unstemmed |
Rol del riñón en la hipertensión sal-sensible |
title_sort |
rol del riñón en la hipertensión sal-sensible |
publisher |
Sociedad Médica de Santiago |
publishDate |
2010 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000700012 |
work_keys_str_mv |
AT ardilesleopoldo roldelrinonenlahipertensionsalsensible AT mezzanosergio roldelrinonenlahipertensionsalsensible |
_version_ |
1718436515824009216 |