El síndrome metabólico: De factor agravante a principal factor de riesgo patogénico en diversas enfermedades crónicas

In recent years, a rapidly increasing number of studies have focused on the association between metabolic syndrome and several chronic diseases. However, it is difficult to determine a well defined pathogenic relationship, due to the etiological heterogeneity and comorbidities of these diseases. Res...

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Autores principales: VON BERNHARDI,ROMMY, ZANLUNGO,SILVANA, ARRESE,MARCO, ARTEAGA,ANTONIO, RIGOTTI,ATTILIO
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2010
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000800012
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spelling oai:scielo:S0034-988720100008000122010-12-21El síndrome metabólico: De factor agravante a principal factor de riesgo patogénico en diversas enfermedades crónicasVON BERNHARDI,ROMMYZANLUNGO,SILVANAARRESE,MARCOARTEAGA,ANTONIORIGOTTI,ATTILIO Chronic disease Hyperinsulinism Metabolic syndrome In recent years, a rapidly increasing number of studies have focused on the association between metabolic syndrome and several chronic diseases. However, it is difficult to determine a well defined pathogenic relationship, due to the etiological heterogeneity and comorbidities of these diseases. Research efforts are aiming to identify the convergent biological mechanisms that mediate the effects of hyperinsulinemia, hyperglycemia, dyslipidemia, and hypertension. All these conditions define the metabolic syndrome, that increases the risk for several diseases. The knowledge of these biological mechanisms associated with this syndrome will elucidate the pathogenic association between a variety of chronic diseases, including its pathogenic link with cardiovascular diseases and the most common forms of dementia. The development of new therapeutic and preventive strategies for these diseases will be a corollary of this research.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.8 20102010-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000800012es10.4067/S0034-98872010000800012
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Chronic disease
Hyperinsulinism
Metabolic syndrome
spellingShingle Chronic disease
Hyperinsulinism
Metabolic syndrome
VON BERNHARDI,ROMMY
ZANLUNGO,SILVANA
ARRESE,MARCO
ARTEAGA,ANTONIO
RIGOTTI,ATTILIO
El síndrome metabólico: De factor agravante a principal factor de riesgo patogénico en diversas enfermedades crónicas
description In recent years, a rapidly increasing number of studies have focused on the association between metabolic syndrome and several chronic diseases. However, it is difficult to determine a well defined pathogenic relationship, due to the etiological heterogeneity and comorbidities of these diseases. Research efforts are aiming to identify the convergent biological mechanisms that mediate the effects of hyperinsulinemia, hyperglycemia, dyslipidemia, and hypertension. All these conditions define the metabolic syndrome, that increases the risk for several diseases. The knowledge of these biological mechanisms associated with this syndrome will elucidate the pathogenic association between a variety of chronic diseases, including its pathogenic link with cardiovascular diseases and the most common forms of dementia. The development of new therapeutic and preventive strategies for these diseases will be a corollary of this research.
author VON BERNHARDI,ROMMY
ZANLUNGO,SILVANA
ARRESE,MARCO
ARTEAGA,ANTONIO
RIGOTTI,ATTILIO
author_facet VON BERNHARDI,ROMMY
ZANLUNGO,SILVANA
ARRESE,MARCO
ARTEAGA,ANTONIO
RIGOTTI,ATTILIO
author_sort VON BERNHARDI,ROMMY
title El síndrome metabólico: De factor agravante a principal factor de riesgo patogénico en diversas enfermedades crónicas
title_short El síndrome metabólico: De factor agravante a principal factor de riesgo patogénico en diversas enfermedades crónicas
title_full El síndrome metabólico: De factor agravante a principal factor de riesgo patogénico en diversas enfermedades crónicas
title_fullStr El síndrome metabólico: De factor agravante a principal factor de riesgo patogénico en diversas enfermedades crónicas
title_full_unstemmed El síndrome metabólico: De factor agravante a principal factor de riesgo patogénico en diversas enfermedades crónicas
title_sort el síndrome metabólico: de factor agravante a principal factor de riesgo patogénico en diversas enfermedades crónicas
publisher Sociedad Médica de Santiago
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000800012
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