Neuroblastoma in an adult: Case report

Neuroblastoma is the most common extracranial solid malignancy in children but rarely described in adults, being 10% of all cases diagnosed after the first decade of life. We report a 23 year-old black woman with a mass at paravertebral region of T3-T5, multiple lesions in vertebral bodies and expan...

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Autores principales:	MIRANDA SOARES,PRISCILA BERNARDINA, QUIRINO FILHO,SIDNEI, PEREIRA DE SOUZA,WILLIAM, FERRETI BONAN,PAULO ROGÉRIO, MARTELLI-JÚNIOR,HERCÍLIO
Lenguaje:	English
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Antineoplastic protocols Drug Therapy Neoplasms Neuroblastoma
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000900007
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spelling	oai:scielo:S0034-988720100009000072010-11-09Neuroblastoma in an adult: Case reportMIRANDA SOARES,PRISCILA BERNARDINAQUIRINO FILHO,SIDNEIPEREIRA DE SOUZA,WILLIAMFERRETI BONAN,PAULO ROGÉRIOMARTELLI-JÚNIOR,HERCÍLIO Antineoplastic protocols Drug Therapy Neoplasms Neuroblastoma Neuroblastoma is the most common extracranial solid malignancy in children but rarely described in adults, being 10% of all cases diagnosed after the first decade of life. We report a 23 year-old black woman with a mass at paravertebral region of T3-T5, multiple lesions in vertebral bodies and expanding skull-brain lesion at the right parietal region. Immunohistochemical analysis (negative for CD99, CD20, CD3 and desmin; and positive chromogranin, synaptophysin and NB84) confi rmed the diagnosis of neuroblastoma. The patient was submitted to 12 cycles of chemotherapy receiving VAC (vincristine/doxorubicin/cyclophosphamide) interspersed with ICE (ifosfamide/mesna/etoposide) and doxorubicin was replaced by actinomycin in the 7th cycle. She had good tolerance to this therapy, and has been clinically stable.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.9 20102010-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000900007en10.4067/S0034-98872010000900007
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Antineoplastic protocols Drug Therapy Neoplasms Neuroblastoma
spellingShingle	Antineoplastic protocols Drug Therapy Neoplasms Neuroblastoma MIRANDA SOARES,PRISCILA BERNARDINA QUIRINO FILHO,SIDNEI PEREIRA DE SOUZA,WILLIAM FERRETI BONAN,PAULO ROGÉRIO MARTELLI-JÚNIOR,HERCÍLIO Neuroblastoma in an adult: Case report
description	Neuroblastoma is the most common extracranial solid malignancy in children but rarely described in adults, being 10% of all cases diagnosed after the first decade of life. We report a 23 year-old black woman with a mass at paravertebral region of T3-T5, multiple lesions in vertebral bodies and expanding skull-brain lesion at the right parietal region. Immunohistochemical analysis (negative for CD99, CD20, CD3 and desmin; and positive chromogranin, synaptophysin and NB84) confi rmed the diagnosis of neuroblastoma. The patient was submitted to 12 cycles of chemotherapy receiving VAC (vincristine/doxorubicin/cyclophosphamide) interspersed with ICE (ifosfamide/mesna/etoposide) and doxorubicin was replaced by actinomycin in the 7th cycle. She had good tolerance to this therapy, and has been clinically stable.
author	MIRANDA SOARES,PRISCILA BERNARDINA QUIRINO FILHO,SIDNEI PEREIRA DE SOUZA,WILLIAM FERRETI BONAN,PAULO ROGÉRIO MARTELLI-JÚNIOR,HERCÍLIO
author_facet	MIRANDA SOARES,PRISCILA BERNARDINA QUIRINO FILHO,SIDNEI PEREIRA DE SOUZA,WILLIAM FERRETI BONAN,PAULO ROGÉRIO MARTELLI-JÚNIOR,HERCÍLIO
author_sort	MIRANDA SOARES,PRISCILA BERNARDINA
title	Neuroblastoma in an adult: Case report
title_short	Neuroblastoma in an adult: Case report
title_full	Neuroblastoma in an adult: Case report
title_fullStr	Neuroblastoma in an adult: Case report
title_full_unstemmed	Neuroblastoma in an adult: Case report
title_sort	neuroblastoma in an adult: case report
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010000900007
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Neuroblastoma in an adult: Case report

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