Efectos de la glicina sobre los trastornos de conducción del nervio auditivo en pacientes diabéticos tipo 2 con otoneuropatía

Background: Glycine inhibits the formation of advanced glycation end products that may cause central and peripheral neuronal damage, affecting also the auditory nerve. Aim: To evaluate the effect of glycine on auditory nerve conduction and hearing level among patients with type 2 diabetes mellitus a...

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Autores principales:	MUÑOZ-CARLIN,MARÍA DE LOURDES, RODRÍGUEZ-MOCTEZUMA,JOSÉ RAYMUNDO, GÓMEZ LATORRE,JUAN GERARDO, MONTES-CASTILLO,MARÍA LUISA, JUÁREZ-ADAUTA,SALVADOR
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Diabetes mellitus Evoked potentials auditory Glycine
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001100006
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spelling	oai:scielo:S0034-988720100011000062011-01-10Efectos de la glicina sobre los trastornos de conducción del nervio auditivo en pacientes diabéticos tipo 2 con otoneuropatíaMUÑOZ-CARLIN,MARÍA DE LOURDESRODRÍGUEZ-MOCTEZUMA,JOSÉ RAYMUNDOGÓMEZ LATORRE,JUAN GERARDOMONTES-CASTILLO,MARÍA LUISAJUÁREZ-ADAUTA,SALVADOR Diabetes mellitus Evoked potentials auditory Glycine Background: Glycine inhibits the formation of advanced glycation end products that may cause central and peripheral neuronal damage, affecting also the auditory nerve. Aim: To evaluate the effect of glycine on auditory nerve conduction and hearing level among patients with type 2 diabetes mellitus and auditory neuropathy. Material and Methods: Twenty grams of oral glycine per day were administered during 6 months to 28 type 2 diabetic patients aged 58 ± 6 years, with auditory pathway neuropathy. Hearing tests and evoked otoacustic potentials were performed regularly. Fifteen diabetic patients aged 49 ± 8 years, without auditory nerve neuropathy did not receive glycine and were followed as a control group. Results: Among patients receiving glycine, a significant improvement in left ear audiometry at 125, 250 and 500 Hz and right ear audiometry at 500 Hz, was observed. Waves I, III and V (p= 0.02) of evoked otoacustic potentials improved significantly in the left ear and wave I in the right ear. Among controls, waves V and III of evoked otoacoustic potentials had a significant impairment in the left ear. Conclusions: There was an improvement in auditory evoked potentials in patients receiving glycine and an impairment in untreated control patients.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.10 20102010-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001100006es10.4067/S0034-98872010001100006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Diabetes mellitus Evoked potentials auditory Glycine
spellingShingle	Diabetes mellitus Evoked potentials auditory Glycine MUÑOZ-CARLIN,MARÍA DE LOURDES RODRÍGUEZ-MOCTEZUMA,JOSÉ RAYMUNDO GÓMEZ LATORRE,JUAN GERARDO MONTES-CASTILLO,MARÍA LUISA JUÁREZ-ADAUTA,SALVADOR Efectos de la glicina sobre los trastornos de conducción del nervio auditivo en pacientes diabéticos tipo 2 con otoneuropatía
description	Background: Glycine inhibits the formation of advanced glycation end products that may cause central and peripheral neuronal damage, affecting also the auditory nerve. Aim: To evaluate the effect of glycine on auditory nerve conduction and hearing level among patients with type 2 diabetes mellitus and auditory neuropathy. Material and Methods: Twenty grams of oral glycine per day were administered during 6 months to 28 type 2 diabetic patients aged 58 ± 6 years, with auditory pathway neuropathy. Hearing tests and evoked otoacustic potentials were performed regularly. Fifteen diabetic patients aged 49 ± 8 years, without auditory nerve neuropathy did not receive glycine and were followed as a control group. Results: Among patients receiving glycine, a significant improvement in left ear audiometry at 125, 250 and 500 Hz and right ear audiometry at 500 Hz, was observed. Waves I, III and V (p= 0.02) of evoked otoacustic potentials improved significantly in the left ear and wave I in the right ear. Among controls, waves V and III of evoked otoacoustic potentials had a significant impairment in the left ear. Conclusions: There was an improvement in auditory evoked potentials in patients receiving glycine and an impairment in untreated control patients.
author	MUÑOZ-CARLIN,MARÍA DE LOURDES RODRÍGUEZ-MOCTEZUMA,JOSÉ RAYMUNDO GÓMEZ LATORRE,JUAN GERARDO MONTES-CASTILLO,MARÍA LUISA JUÁREZ-ADAUTA,SALVADOR
author_facet	MUÑOZ-CARLIN,MARÍA DE LOURDES RODRÍGUEZ-MOCTEZUMA,JOSÉ RAYMUNDO GÓMEZ LATORRE,JUAN GERARDO MONTES-CASTILLO,MARÍA LUISA JUÁREZ-ADAUTA,SALVADOR
author_sort	MUÑOZ-CARLIN,MARÍA DE LOURDES
title	Efectos de la glicina sobre los trastornos de conducción del nervio auditivo en pacientes diabéticos tipo 2 con otoneuropatía
title_short	Efectos de la glicina sobre los trastornos de conducción del nervio auditivo en pacientes diabéticos tipo 2 con otoneuropatía
title_full	Efectos de la glicina sobre los trastornos de conducción del nervio auditivo en pacientes diabéticos tipo 2 con otoneuropatía
title_fullStr	Efectos de la glicina sobre los trastornos de conducción del nervio auditivo en pacientes diabéticos tipo 2 con otoneuropatía
title_full_unstemmed	Efectos de la glicina sobre los trastornos de conducción del nervio auditivo en pacientes diabéticos tipo 2 con otoneuropatía
title_sort	efectos de la glicina sobre los trastornos de conducción del nervio auditivo en pacientes diabéticos tipo 2 con otoneuropatía
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001100006
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Efectos de la glicina sobre los trastornos de conducción del nervio auditivo en pacientes diabéticos tipo 2 con otoneuropatía

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