Espondilodiscitis tuberculosa en Cádiz (España) durante diez años

Background: Tuberculous spondylodiscitis is relatively uncommon but represents the most common location of osseous tuberculosis. Aim: To describe clinical features, imaging studies and laboratory tests to establish the diagnosis in a group of patients living in Cádiz (Spain). Material and Methods: R...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: LOZANO,MARÍA CARMEN, GARCÍA-AGUDO,LIDIA, MORENO,RAQUEL, CHOZAS,NICOLÁS, GARCÍA-MARTOS,PEDRO
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2010
Materias:
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001100010
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:scielo:S0034-98872010001100010
record_format dspace
spelling oai:scielo:S0034-988720100011000102011-01-10Espondilodiscitis tuberculosa en Cádiz (España) durante diez añosLOZANO,MARÍA CARMENGARCÍA-AGUDO,LIDIAMORENO,RAQUELCHOZAS,NICOLÁSGARCÍA-MARTOS,PEDRO Discitis Spondylitis Tuberculosis osteoarticular Background: Tuberculous spondylodiscitis is relatively uncommon but represents the most common location of osseous tuberculosis. Aim: To describe clinical features, imaging studies and laboratory tests to establish the diagnosis in a group of patients living in Cádiz (Spain). Material and Methods: Retrospective analysis of medical records of patients with tuberculous spondylodiscitis diagnosed between 2000 and 2009. The diagnosis was based on microorganism recovery from vertebral samples obtained by imaging guided biopsies. Results: Six patients with positive Mycobac-terium tuberculosis cultures from vertebral samples, were identified (10% of extra-pulmonary tuberculosis). In only 2 patients the Ziehl-Nielsen stain was positive, and histology was compatible in 4 cases. Four patients were females, their mean age was 54.3 years and the mean duration of symptoms was 7.3 months. Three patients had lumbar location and a positive Mantoux test. A soft tissue abscess was present in 4 cases. None of these patients had neurological complications. The treatment with four tuberculostatic agents (isoniazid, rifampicin, pyrazinamide and ethambutol) was effective in 5 patients. Conclusions: Tuberculous spondylodiscitis may become a serious disease due to diagnostic and treatment delays. The main examinations to establish diagnosis are magnetic resonance imaging and biopsy with microbiological culture. Generally, antituberculous therapy is effective in this clinical situation.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.10 20102010-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001100010es10.4067/S0034-98872010001100010
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Discitis
Spondylitis
Tuberculosis
osteoarticular
spellingShingle Discitis
Spondylitis
Tuberculosis
osteoarticular
LOZANO,MARÍA CARMEN
GARCÍA-AGUDO,LIDIA
MORENO,RAQUEL
CHOZAS,NICOLÁS
GARCÍA-MARTOS,PEDRO
Espondilodiscitis tuberculosa en Cádiz (España) durante diez años
description Background: Tuberculous spondylodiscitis is relatively uncommon but represents the most common location of osseous tuberculosis. Aim: To describe clinical features, imaging studies and laboratory tests to establish the diagnosis in a group of patients living in Cádiz (Spain). Material and Methods: Retrospective analysis of medical records of patients with tuberculous spondylodiscitis diagnosed between 2000 and 2009. The diagnosis was based on microorganism recovery from vertebral samples obtained by imaging guided biopsies. Results: Six patients with positive Mycobac-terium tuberculosis cultures from vertebral samples, were identified (10% of extra-pulmonary tuberculosis). In only 2 patients the Ziehl-Nielsen stain was positive, and histology was compatible in 4 cases. Four patients were females, their mean age was 54.3 years and the mean duration of symptoms was 7.3 months. Three patients had lumbar location and a positive Mantoux test. A soft tissue abscess was present in 4 cases. None of these patients had neurological complications. The treatment with four tuberculostatic agents (isoniazid, rifampicin, pyrazinamide and ethambutol) was effective in 5 patients. Conclusions: Tuberculous spondylodiscitis may become a serious disease due to diagnostic and treatment delays. The main examinations to establish diagnosis are magnetic resonance imaging and biopsy with microbiological culture. Generally, antituberculous therapy is effective in this clinical situation.
author LOZANO,MARÍA CARMEN
GARCÍA-AGUDO,LIDIA
MORENO,RAQUEL
CHOZAS,NICOLÁS
GARCÍA-MARTOS,PEDRO
author_facet LOZANO,MARÍA CARMEN
GARCÍA-AGUDO,LIDIA
MORENO,RAQUEL
CHOZAS,NICOLÁS
GARCÍA-MARTOS,PEDRO
author_sort LOZANO,MARÍA CARMEN
title Espondilodiscitis tuberculosa en Cádiz (España) durante diez años
title_short Espondilodiscitis tuberculosa en Cádiz (España) durante diez años
title_full Espondilodiscitis tuberculosa en Cádiz (España) durante diez años
title_fullStr Espondilodiscitis tuberculosa en Cádiz (España) durante diez años
title_full_unstemmed Espondilodiscitis tuberculosa en Cádiz (España) durante diez años
title_sort espondilodiscitis tuberculosa en cádiz (españa) durante diez años
publisher Sociedad Médica de Santiago
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001100010
work_keys_str_mv AT lozanomariacarmen espondilodiscitistuberculosaencadizespanadurantediezanos
AT garciaagudolidia espondilodiscitistuberculosaencadizespanadurantediezanos
AT morenoraquel espondilodiscitistuberculosaencadizespanadurantediezanos
AT chozasnicolas espondilodiscitistuberculosaencadizespanadurantediezanos
AT garciamartospedro espondilodiscitistuberculosaencadizespanadurantediezanos
_version_ 1718436532554039296