Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico?

Vitamin D has an essential role in calcium metabolism and bone health. Vitamin D3 or cholecalciferol is synthesized from 7-dehydrocholesterol or provitamin D3, by sunlight ultraviolet radiation to the skin. 7-dehydrocholesterol is subsequently hydroxylated in the liver and then in the kidney to prod...

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Autores principales:	QUERALES,MARVIN ISAAC, CRUCES,MARÍA ELENA, ROJAS,SUSAN, SÁNCHEZ,LISSETTE
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Insulin resistance Vitamin D Metabolic syndrome X
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001100017
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spelling	oai:scielo:S0034-988720100011000172011-01-10Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico?QUERALES,MARVIN ISAACCRUCES,MARÍA ELENAROJAS,SUSANSÁNCHEZ,LISSETTE Insulin resistance Vitamin D Metabolic syndrome X Vitamin D has an essential role in calcium metabolism and bone health. Vitamin D3 or cholecalciferol is synthesized from 7-dehydrocholesterol or provitamin D3, by sunlight ultraviolet radiation to the skin. 7-dehydrocholesterol is subsequently hydroxylated in the liver and then in the kidney to produce 1,25-(OH)2D3, the active metabolite that binds to specific receptors (VDR) in target tissues, mainly bone and intestine. Other tissues, such as the immune and cardiovascular system, have also VDR. Vitamin D deficiency can induce rickets in children and osteomalacia and osteoporosis in adults. A possible inverse association between vitamin D levels and the prevalence of metabolic syndrome has been proposed. Vitamin D deficiency increases the risk of type 1 diabetes, insulin resistance, and hypertension, key components of this syndrome. However, other studies have not confirmed this association. Further clinical and experimental studies are needed to ascertain the role of vitamin D in metabolic syndrome.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.10 20102010-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001100017es10.4067/S0034-98872010001100017
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Insulin resistance Vitamin D Metabolic syndrome X
spellingShingle	Insulin resistance Vitamin D Metabolic syndrome X QUERALES,MARVIN ISAAC CRUCES,MARÍA ELENA ROJAS,SUSAN SÁNCHEZ,LISSETTE Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico?
description	Vitamin D has an essential role in calcium metabolism and bone health. Vitamin D3 or cholecalciferol is synthesized from 7-dehydrocholesterol or provitamin D3, by sunlight ultraviolet radiation to the skin. 7-dehydrocholesterol is subsequently hydroxylated in the liver and then in the kidney to produce 1,25-(OH)2D3, the active metabolite that binds to specific receptors (VDR) in target tissues, mainly bone and intestine. Other tissues, such as the immune and cardiovascular system, have also VDR. Vitamin D deficiency can induce rickets in children and osteomalacia and osteoporosis in adults. A possible inverse association between vitamin D levels and the prevalence of metabolic syndrome has been proposed. Vitamin D deficiency increases the risk of type 1 diabetes, insulin resistance, and hypertension, key components of this syndrome. However, other studies have not confirmed this association. Further clinical and experimental studies are needed to ascertain the role of vitamin D in metabolic syndrome.
author	QUERALES,MARVIN ISAAC CRUCES,MARÍA ELENA ROJAS,SUSAN SÁNCHEZ,LISSETTE
author_facet	QUERALES,MARVIN ISAAC CRUCES,MARÍA ELENA ROJAS,SUSAN SÁNCHEZ,LISSETTE
author_sort	QUERALES,MARVIN ISAAC
title	Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico?
title_short	Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico?
title_full	Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico?
title_fullStr	Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico?
title_full_unstemmed	Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico?
title_sort	deficiencia de vitamina d: ¿factor de riesgo de síndrome metabólico?
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001100017
work_keys_str_mv	AT queralesmarvinisaac deficienciadevitaminadfactorderiesgodesindromemetabolico AT crucesmariaelena deficienciadevitaminadfactorderiesgodesindromemetabolico AT rojassusan deficienciadevitaminadfactorderiesgodesindromemetabolico AT sanchezlissette deficienciadevitaminadfactorderiesgodesindromemetabolico
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Deficiencia de vitamina D: ¿Factor de riesgo de síndrome metabólico?

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