Enfermedad pulmonar obstructiva crónica: Mirada actual a una enfermedad emergente

Chronic obstructive pulmonary disease (COPD), mainly caused by smoking, is predicted to be the third most frequent cause of death in the world by 2020. It is a multicomponent, progressive, disabling condition that ultimately ends in respiratory failure and death. There is evidence that systemic infl...

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Autor principal:	SILVA O,RAFAEL
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2010
Materias:	Cause of death Clinical protocols Pulmonary disease chronic obstructive
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001300012
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spelling	oai:scielo:S0034-988720100013000122011-02-07Enfermedad pulmonar obstructiva crónica: Mirada actual a una enfermedad emergenteSILVA O,RAFAEL Cause of death Clinical protocols Pulmonary disease chronic obstructive Chronic obstructive pulmonary disease (COPD), mainly caused by smoking, is predicted to be the third most frequent cause of death in the world by 2020. It is a multicomponent, progressive, disabling condition that ultimately ends in respiratory failure and death. There is evidence that systemic inflammation and extra pulmonary effects are also common in COPD, although the association between systemic inflammation and systemic manifestations of COPD is still not entirely clear. COPD is not only preventable but also treatable and the past decade has witnessed great progress in COPD research. New drugs have been developed and tested and a growing base of scientifc evidence now documents the efficacy of several therapies for symptoms and exacerbations. It is clear that many patients with the disease can beneft from an aggressive management, with a decrease in the frequency of hospitalizations and improvements in symptoms and quality of life. Moreover, basic and clinical scientists have now identifed cells, mechanisms, and molecules that play key roles in its pathogenesis. The advent of newer and more effective therapies will lead to a decline in the contribution of this disease to worldwide disease burden. COPD is now viewed under a new paradigm as preventable and treatable.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.138 n.12 20102010-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001300012es10.4067/S0034-98872010001300012
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Cause of death Clinical protocols Pulmonary disease chronic obstructive
spellingShingle	Cause of death Clinical protocols Pulmonary disease chronic obstructive SILVA O,RAFAEL Enfermedad pulmonar obstructiva crónica: Mirada actual a una enfermedad emergente
description	Chronic obstructive pulmonary disease (COPD), mainly caused by smoking, is predicted to be the third most frequent cause of death in the world by 2020. It is a multicomponent, progressive, disabling condition that ultimately ends in respiratory failure and death. There is evidence that systemic inflammation and extra pulmonary effects are also common in COPD, although the association between systemic inflammation and systemic manifestations of COPD is still not entirely clear. COPD is not only preventable but also treatable and the past decade has witnessed great progress in COPD research. New drugs have been developed and tested and a growing base of scientifc evidence now documents the efficacy of several therapies for symptoms and exacerbations. It is clear that many patients with the disease can beneft from an aggressive management, with a decrease in the frequency of hospitalizations and improvements in symptoms and quality of life. Moreover, basic and clinical scientists have now identifed cells, mechanisms, and molecules that play key roles in its pathogenesis. The advent of newer and more effective therapies will lead to a decline in the contribution of this disease to worldwide disease burden. COPD is now viewed under a new paradigm as preventable and treatable.
author	SILVA O,RAFAEL
author_facet	SILVA O,RAFAEL
author_sort	SILVA O,RAFAEL
title	Enfermedad pulmonar obstructiva crónica: Mirada actual a una enfermedad emergente
title_short	Enfermedad pulmonar obstructiva crónica: Mirada actual a una enfermedad emergente
title_full	Enfermedad pulmonar obstructiva crónica: Mirada actual a una enfermedad emergente
title_fullStr	Enfermedad pulmonar obstructiva crónica: Mirada actual a una enfermedad emergente
title_full_unstemmed	Enfermedad pulmonar obstructiva crónica: Mirada actual a una enfermedad emergente
title_sort	enfermedad pulmonar obstructiva crónica: mirada actual a una enfermedad emergente
publisher	Sociedad Médica de Santiago
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872010001300012
work_keys_str_mv	AT silvaorafael enfermedadpulmonarobstructivacronicamiradaactualaunaenfermedademergente
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Enfermedad pulmonar obstructiva crónica: Mirada actual a una enfermedad emergente

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