Resultados Chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento ST: ACCORD (ACute CORonary syndrome Descriptive study)

Background: Guidelines for the management of unstable angina (UA) and non ST elevation myocardial infarction (NSTEMI) have been issued, however cu-rrent practices are unknown in Chile. Aitn: To evalúate in a prospective cohort of NSTEMI patients the current practices, treatments and risk factors. Ma...

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Autores principales:	STOCKINS,BENJAMÍN, ALBORNOZ,FRANCISCO, MARTÍNEZ,DARÍO, CAMPOS,PABLA, GAJARDO,JORGE, LAMICH,RUBÉN, MANRÍQUEZ,LEOPOLDO, PÉREZ,VÍCTOR, ROJO,PAMELA, SEPÚLVEDA,PABLO, PUMARINO,M. GABRIELA, CORBALÁN,RAMÓN
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Coronary artery disease Myocardial infarction Risk factors
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000100003
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spelling	oai:scielo:S0034-988720110001000032011-04-11Resultados Chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento ST: ACCORD (ACute CORonary syndrome Descriptive study)STOCKINS,BENJAMÍNALBORNOZ,FRANCISCOMARTÍNEZ,DARÍOCAMPOS,PABLAGAJARDO,JORGELAMICH,RUBÉNMANRÍQUEZ,LEOPOLDOPÉREZ,VÍCTORROJO,PAMELASEPÚLVEDA,PABLOPUMARINO,M. GABRIELACORBALÁN,RAMÓN Coronary artery disease Myocardial infarction Risk factors Background: Guidelines for the management of unstable angina (UA) and non ST elevation myocardial infarction (NSTEMI) have been issued, however cu-rrent practices are unknown in Chile. Aitn: To evalúate in a prospective cohort of NSTEMI patients the current practices, treatments and risk factors. Material and Methods: Oneyear prospective International non interventional registry, conducted in Chile between January 2005 and November 2006. Results: Two hundred thirty three Chilean NSTEMI patients were enrolled. Mortality was 5.5% at the end ofthe follow-up. Mean age was 61.6 years, and 30.6% were female. Most of the patients had at least one risk factor (98%): hypertension (84%), previous myocardial infarction (33%), dyslipidemia (54%), diabetes (33%), current smoking (30%). Main procedures duringthe hospitalization were coronary angiogram (67%), angioplasty (33%; 88% with stent) and coronary bypass surgery (7%). Duringprocedures, 31% of patients received clopidogrel, and 4.2% glycoprotein Ilb/IIIa antagonists. Medical management was selected for 60% of patients. In comparison to men, women received less interventional procedures despite havingmore risk factors. Treatments prescribed at discharge were aspirin (97%), clopidogrel (49%), beta blockers (78%), diuretics (21%), lipid lowering agents (78%), oral hypoglycemic agents (13%) and insulin (9%). At the end ofthe 1-year follow-up, treatments were aspirin (84%), beta blockers (72%), diuretics (19%), and dual antiplatelet therapy with clopidogrel (16%). Conclusions: A high prevalence of múltiple risk factors for cardiovascular disease in Chilean patients with NSTEMI was observed. More aggressive primary and secondary preventive measures are urgently needed. Use of therapies proposed in the guidelines is high, but dual antiplatelet therapy is less than 50% at discharge and decreases during the one year-follow-up.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.1 20112011-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000100003es10.4067/S0034-98872011000100003
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Coronary artery disease Myocardial infarction Risk factors
spellingShingle	Coronary artery disease Myocardial infarction Risk factors STOCKINS,BENJAMÍN ALBORNOZ,FRANCISCO MARTÍNEZ,DARÍO CAMPOS,PABLA GAJARDO,JORGE LAMICH,RUBÉN MANRÍQUEZ,LEOPOLDO PÉREZ,VÍCTOR ROJO,PAMELA SEPÚLVEDA,PABLO PUMARINO,M. GABRIELA CORBALÁN,RAMÓN Resultados Chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento ST: ACCORD (ACute CORonary syndrome Descriptive study)
description	Background: Guidelines for the management of unstable angina (UA) and non ST elevation myocardial infarction (NSTEMI) have been issued, however cu-rrent practices are unknown in Chile. Aitn: To evalúate in a prospective cohort of NSTEMI patients the current practices, treatments and risk factors. Material and Methods: Oneyear prospective International non interventional registry, conducted in Chile between January 2005 and November 2006. Results: Two hundred thirty three Chilean NSTEMI patients were enrolled. Mortality was 5.5% at the end ofthe follow-up. Mean age was 61.6 years, and 30.6% were female. Most of the patients had at least one risk factor (98%): hypertension (84%), previous myocardial infarction (33%), dyslipidemia (54%), diabetes (33%), current smoking (30%). Main procedures duringthe hospitalization were coronary angiogram (67%), angioplasty (33%; 88% with stent) and coronary bypass surgery (7%). Duringprocedures, 31% of patients received clopidogrel, and 4.2% glycoprotein Ilb/IIIa antagonists. Medical management was selected for 60% of patients. In comparison to men, women received less interventional procedures despite havingmore risk factors. Treatments prescribed at discharge were aspirin (97%), clopidogrel (49%), beta blockers (78%), diuretics (21%), lipid lowering agents (78%), oral hypoglycemic agents (13%) and insulin (9%). At the end ofthe 1-year follow-up, treatments were aspirin (84%), beta blockers (72%), diuretics (19%), and dual antiplatelet therapy with clopidogrel (16%). Conclusions: A high prevalence of múltiple risk factors for cardiovascular disease in Chilean patients with NSTEMI was observed. More aggressive primary and secondary preventive measures are urgently needed. Use of therapies proposed in the guidelines is high, but dual antiplatelet therapy is less than 50% at discharge and decreases during the one year-follow-up.
author	STOCKINS,BENJAMÍN ALBORNOZ,FRANCISCO MARTÍNEZ,DARÍO CAMPOS,PABLA GAJARDO,JORGE LAMICH,RUBÉN MANRÍQUEZ,LEOPOLDO PÉREZ,VÍCTOR ROJO,PAMELA SEPÚLVEDA,PABLO PUMARINO,M. GABRIELA CORBALÁN,RAMÓN
author_facet	STOCKINS,BENJAMÍN ALBORNOZ,FRANCISCO MARTÍNEZ,DARÍO CAMPOS,PABLA GAJARDO,JORGE LAMICH,RUBÉN MANRÍQUEZ,LEOPOLDO PÉREZ,VÍCTOR ROJO,PAMELA SEPÚLVEDA,PABLO PUMARINO,M. GABRIELA CORBALÁN,RAMÓN
author_sort	STOCKINS,BENJAMÍN
title	Resultados Chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento ST: ACCORD (ACute CORonary syndrome Descriptive study)
title_short	Resultados Chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento ST: ACCORD (ACute CORonary syndrome Descriptive study)
title_full	Resultados Chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento ST: ACCORD (ACute CORonary syndrome Descriptive study)
title_fullStr	Resultados Chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento ST: ACCORD (ACute CORonary syndrome Descriptive study)
title_full_unstemmed	Resultados Chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento ST: ACCORD (ACute CORonary syndrome Descriptive study)
title_sort	resultados chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento st: accord (acute coronary syndrome descriptive study)
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000100003
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Resultados Chilenos del registro internacional de factores de riesgo y tratamiento de angina inestable e infarto al miocardio sin supradesnivel del segmento ST: ACCORD (ACute CORonary syndrome Descriptive study)

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