Impacto clínico de la influenza A H1N1 pandémica en el hospital de Puerto Montt, Chile

Background: Pandemic flu (H1N1 ) strongly affected southern Chile during2009. Aim: To report the logistic and organizational changes implemented at a regional hospital to face the pandemic. Material and Methods: All patients with flu like disease that were hospitalized, were prospectively enrolled a...

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Autores principales:	Riquelme O,Raúl, Riquelme O,Mauricio, Rioseco Z,María Luisa, Inzunza P,Carlos, Contreras G,Cristian, Gómez V,Yarella, Riquelme D,Javier
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2011
Materias:	Fluorescent antibody technique H1N1 virus Influenza human
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000300006
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spelling	oai:scielo:S0034-988720110003000062011-08-25Impacto clínico de la influenza A H1N1 pandémica en el hospital de Puerto Montt, ChileRiquelme O,RaúlRiquelme O,MauricioRioseco Z,María LuisaInzunza P,CarlosContreras G,CristianGómez V,YarellaRiquelme D,Javier Fluorescent antibody technique H1N1 virus Influenza human Background: Pandemic flu (H1N1 ) strongly affected southern Chile during2009. Aim: To report the logistic and organizational changes implemented at a regional hospital to face the pandemic. Material and Methods: All patients with flu like disease that were hospitalized, were prospectively enrolled at the Puerto Montt hospital. A nasopharyngeal aspirate was obtained in all for influenza virus A and B direct immunofluorescence and polymerase chain reaction (PCR). All epidemiological and clinical data of patients were recorded. Results: Between May 29 and July 7, 2009, 184 adults were admitted to the hospital and in 117patients aged 41 ± 18 years (56% females ), direct immunofluorescence was positive for influenza. In 67 of these patients PCR did not confirm the disease. These unconfirmed patients had a mean age of 49 ± 19 years (p < 0.01, compared with confirmed cases) and had a lower frequency of fever, rhinorrhea and chills. No significant differences in the incidence of community acquired pneumonia or chest X ray findings were observed between confirmed and unconfirmed cases. Hospital stay was over 15 days in 14% of confirmed cases and 5% of unconfirmed cases (p = 0.03). Fifteen patients, aged 53 ± 18 years, died. Conclusions: Low sensibility of direct immunofluorescence and delay in obtaining PCR confirmation of influenza posed a problem for the management of these patients.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.139 n.3 20112011-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000300006es10.4067/S0034-98872011000300006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Fluorescent antibody technique H1N1 virus Influenza human
spellingShingle	Fluorescent antibody technique H1N1 virus Influenza human Riquelme O,Raúl Riquelme O,Mauricio Rioseco Z,María Luisa Inzunza P,Carlos Contreras G,Cristian Gómez V,Yarella Riquelme D,Javier Impacto clínico de la influenza A H1N1 pandémica en el hospital de Puerto Montt, Chile
description	Background: Pandemic flu (H1N1 ) strongly affected southern Chile during2009. Aim: To report the logistic and organizational changes implemented at a regional hospital to face the pandemic. Material and Methods: All patients with flu like disease that were hospitalized, were prospectively enrolled at the Puerto Montt hospital. A nasopharyngeal aspirate was obtained in all for influenza virus A and B direct immunofluorescence and polymerase chain reaction (PCR). All epidemiological and clinical data of patients were recorded. Results: Between May 29 and July 7, 2009, 184 adults were admitted to the hospital and in 117patients aged 41 ± 18 years (56% females ), direct immunofluorescence was positive for influenza. In 67 of these patients PCR did not confirm the disease. These unconfirmed patients had a mean age of 49 ± 19 years (p < 0.01, compared with confirmed cases) and had a lower frequency of fever, rhinorrhea and chills. No significant differences in the incidence of community acquired pneumonia or chest X ray findings were observed between confirmed and unconfirmed cases. Hospital stay was over 15 days in 14% of confirmed cases and 5% of unconfirmed cases (p = 0.03). Fifteen patients, aged 53 ± 18 years, died. Conclusions: Low sensibility of direct immunofluorescence and delay in obtaining PCR confirmation of influenza posed a problem for the management of these patients.
author	Riquelme O,Raúl Riquelme O,Mauricio Rioseco Z,María Luisa Inzunza P,Carlos Contreras G,Cristian Gómez V,Yarella Riquelme D,Javier
author_facet	Riquelme O,Raúl Riquelme O,Mauricio Rioseco Z,María Luisa Inzunza P,Carlos Contreras G,Cristian Gómez V,Yarella Riquelme D,Javier
author_sort	Riquelme O,Raúl
title	Impacto clínico de la influenza A H1N1 pandémica en el hospital de Puerto Montt, Chile
title_short	Impacto clínico de la influenza A H1N1 pandémica en el hospital de Puerto Montt, Chile
title_full	Impacto clínico de la influenza A H1N1 pandémica en el hospital de Puerto Montt, Chile
title_fullStr	Impacto clínico de la influenza A H1N1 pandémica en el hospital de Puerto Montt, Chile
title_full_unstemmed	Impacto clínico de la influenza A H1N1 pandémica en el hospital de Puerto Montt, Chile
title_sort	impacto clínico de la influenza a h1n1 pandémica en el hospital de puerto montt, chile
publisher	Sociedad Médica de Santiago
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872011000300006
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Impacto clínico de la influenza A H1N1 pandémica en el hospital de Puerto Montt, Chile

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